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ATG14 (autophagy related 14)

Identity

Alias_namesKIAA0831
KIAA0831
ATG14 autophagy related 14 homolog (S. cerevisiae)
Alias_symbol (synonym)ATG14L
Other aliasBARKOR
HGNC (Hugo) ATG14
LocusID (NCBI) 22863
Atlas_Id 56434
Location 14q22.3  [Link to chromosome band 14q22]
Location_base_pair Starts at 55366391 and ends at 55411858 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATG14 (14q22.3) / FUT8 (14q23.3)ATG14 (14q22.3) / KTN1-AS1 (14q22.3)STRBP (9q33.3) / ATG14 (14q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATG14   19962
Cards
Entrez_Gene (NCBI)ATG14  22863  autophagy related 14
AliasesATG14L; BARKOR; KIAA0831
GeneCards (Weizmann)ATG14
Ensembl hg19 (Hinxton)ENSG00000126775 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126775 [Gene_View]  chr14:55366391-55411858 [Contig_View]  ATG14 [Vega]
ICGC DataPortalENSG00000126775
TCGA cBioPortalATG14
AceView (NCBI)ATG14
Genatlas (Paris)ATG14
WikiGenes22863
SOURCE (Princeton)ATG14
Genetics Home Reference (NIH)ATG14
Genomic and cartography
GoldenPath hg38 (UCSC)ATG14  -     chr14:55366391-55411858 -  14q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATG14  -     14q22.3   [Description]    (hg19-Feb_2009)
EnsemblATG14 - 14q22.3 [CytoView hg19]  ATG14 - 14q22.3 [CytoView hg38]
Mapping of homologs : NCBIATG14 [Mapview hg19]  ATG14 [Mapview hg38]
OMIM613515   
Gene and transcription
Genbank (Entrez)AA988343 AK131251 AK292810 AL049978 BC028015
RefSeq transcript (Entrez)NM_014924
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATG14
Cluster EST : UnigeneHs.414809 [ NCBI ]
CGAP (NCI)Hs.414809
Alternative Splicing GalleryENSG00000126775
Gene ExpressionATG14 [ NCBI-GEO ]   ATG14 [ EBI - ARRAY_EXPRESS ]   ATG14 [ SEEK ]   ATG14 [ MEM ]
Gene Expression Viewer (FireBrowse)ATG14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22863
GTEX Portal (Tissue expression)ATG14
Human Protein AtlasENSG00000126775-ATG14 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZNE5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZNE5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZNE5
Splice isoforms : SwissVarQ6ZNE5
PhosPhoSitePlusQ6ZNE5
Domains : Interpro (EBI)UV_resistance/autophagy_Atg14   
Domain families : Pfam (Sanger)Atg14 (PF10186)   
Domain families : Pfam (NCBI)pfam10186   
Conserved Domain (NCBI)ATG14
DMDM Disease mutations22863
Blocks (Seattle)ATG14
SuperfamilyQ6ZNE5
Human Protein Atlas [tissue]ENSG00000126775-ATG14 [tissue]
Peptide AtlasQ6ZNE5
HPRD13820
IPIIPI00007211   IPI00604698   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZNE5
IntAct (EBI)Q6ZNE5
FunCoupENSG00000126775
BioGRIDATG14
STRING (EMBL)ATG14
ZODIACATG14
Ontologies - Pathways
QuickGOQ6ZNE5
Ontology : AmiGOautophagosome assembly  autophagosome membrane  macromitophagy  regulation of protein phosphorylation  negative regulation of protein phosphorylation  positive regulation of protein phosphorylation  protein binding  autophagosome  endoplasmic reticulum membrane  cytosol  axoneme  endosome to lysosome transport  cellular response to starvation  positive regulation of autophagy  posttranscriptional regulation of gene expression  macroautophagy  macroautophagy  autophagosome docking  pre-autophagosomal structure membrane  pre-autophagosomal structure membrane  phosphatidylinositol 3-kinase complex, class III  cellular response to glucose starvation  positive regulation of phosphatidylinositol 3-kinase activity  ER-mitochondrion membrane contact site  phagocytic vesicle  regulation of protein complex stability  regulation of triglyceride metabolic process  extrinsic component of omegasome membrane  extrinsic component of pre-autophagosomal structure membrane  response to mitochondrial depolarisation  
Ontology : EGO-EBIautophagosome assembly  autophagosome membrane  macromitophagy  regulation of protein phosphorylation  negative regulation of protein phosphorylation  positive regulation of protein phosphorylation  protein binding  autophagosome  endoplasmic reticulum membrane  cytosol  axoneme  endosome to lysosome transport  cellular response to starvation  positive regulation of autophagy  posttranscriptional regulation of gene expression  macroautophagy  macroautophagy  autophagosome docking  pre-autophagosomal structure membrane  pre-autophagosomal structure membrane  phosphatidylinositol 3-kinase complex, class III  cellular response to glucose starvation  positive regulation of phosphatidylinositol 3-kinase activity  ER-mitochondrion membrane contact site  phagocytic vesicle  regulation of protein complex stability  regulation of triglyceride metabolic process  extrinsic component of omegasome membrane  extrinsic component of pre-autophagosomal structure membrane  response to mitochondrial depolarisation  
Pathways : KEGGRegulation of autophagy   
NDEx NetworkATG14
Atlas of Cancer Signalling NetworkATG14
Wikipedia pathwaysATG14
Orthology - Evolution
OrthoDB22863
GeneTree (enSembl)ENSG00000126775
Phylogenetic Trees/Animal Genes : TreeFamATG14
HOVERGENQ6ZNE5
HOGENOMQ6ZNE5
Homologs : HomoloGeneATG14
Homology/Alignments : Family Browser (UCSC)ATG14
Gene fusions - Rearrangements
Fusion: Tumor Portal ATG14
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATG14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATG14
dbVarATG14
ClinVarATG14
1000_GenomesATG14 
Exome Variant ServerATG14
ExAC (Exome Aggregation Consortium)ENSG00000126775
GNOMAD BrowserENSG00000126775
Genetic variants : HAPMAP22863
Genomic Variants (DGV)ATG14 [DGVbeta]
DECIPHERATG14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATG14 
Mutations
ICGC Data PortalATG14 
TCGA Data PortalATG14 
Broad Tumor PortalATG14
OASIS PortalATG14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATG14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATG14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATG14
DgiDB (Drug Gene Interaction Database)ATG14
DoCM (Curated mutations)ATG14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATG14 (select a term)
intoGenATG14
Cancer3DATG14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613515   
Orphanet
MedgenATG14
Genetic Testing Registry ATG14
NextProtQ6ZNE5 [Medical]
TSGene22863
GENETestsATG14
Target ValidationATG14
Huge Navigator ATG14 [HugePedia]
snp3D : Map Gene to Disease22863
BioCentury BCIQATG14
ClinGenATG14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22863
Chemical/Pharm GKB GenePA165478560
Clinical trialATG14
Miscellaneous
canSAR (ICR)ATG14 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATG14
EVEXATG14
GoPubMedATG14
iHOPATG14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:41:14 CET 2017

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