Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ATG16L1 (autophagy related 16 like 1)

Identity

Alias_namesAPG16L
ATG16L
APG16 autophagy 16-like (S. cerevisiae)
ATG16 autophagy related 16-like (S. cerevisiae)
ATG16 autophagy related 16-like 1 (S. cerevisiae)
Alias_symbol (synonym)WDR30
FLJ10035
ATG16A
Other aliasIBD10
HGNC (Hugo) ATG16L1
LocusID (NCBI) 55054
Atlas_Id 52882
Location 2q37.1  [Link to chromosome band 2q37]
Location_base_pair Starts at 233251571 and ends at 233295674 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATG16L1 (2q37.1) / INPP5D (2q37.1)DGKD (2q37.1) / ATG16L1 (2q37.1)DGKD 2q37.1 / ATG16L1 2q37.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATG16L1   21498
Cards
Entrez_Gene (NCBI)ATG16L1  55054  autophagy related 16 like 1
AliasesAPG16L; ATG16A; ATG16L; IBD10; 
WDR30
GeneCards (Weizmann)ATG16L1
Ensembl hg19 (Hinxton)ENSG00000085978 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000085978 [Gene_View]  chr2:233251571-233295674 [Contig_View]  ATG16L1 [Vega]
ICGC DataPortalENSG00000085978
TCGA cBioPortalATG16L1
AceView (NCBI)ATG16L1
Genatlas (Paris)ATG16L1
WikiGenes55054
SOURCE (Princeton)ATG16L1
Genetics Home Reference (NIH)ATG16L1
Genomic and cartography
GoldenPath hg38 (UCSC)ATG16L1  -     chr2:233251571-233295674 +  2q37.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATG16L1  -     2q37.1   [Description]    (hg19-Feb_2009)
EnsemblATG16L1 - 2q37.1 [CytoView hg19]  ATG16L1 - 2q37.1 [CytoView hg38]
Mapping of homologs : NCBIATG16L1 [Mapview hg19]  ATG16L1 [Mapview hg38]
OMIM610767   611081   
Gene and transcription
Genbank (Entrez)AA809053 AK000897 AK001690 AK024453 AK026330
RefSeq transcript (Entrez)NM_001190266 NM_001190267 NM_017974 NM_030803 NM_198890
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATG16L1
Cluster EST : UnigeneHs.529322 [ NCBI ]
CGAP (NCI)Hs.529322
Alternative Splicing GalleryENSG00000085978
Gene ExpressionATG16L1 [ NCBI-GEO ]   ATG16L1 [ EBI - ARRAY_EXPRESS ]   ATG16L1 [ SEEK ]   ATG16L1 [ MEM ]
Gene Expression Viewer (FireBrowse)ATG16L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55054
GTEX Portal (Tissue expression)ATG16L1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ676U5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ676U5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ676U5
Splice isoforms : SwissVarQ676U5
PhosPhoSitePlusQ676U5
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)Autophagy-rel_prot_16    G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)ATG16 (PF08614)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam08614    pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)ATG16L1
DMDM Disease mutations55054
Blocks (Seattle)ATG16L1
PDB (SRS)4GDK    4GDL    4NAW    4TQ0    5D7G   
PDB (PDBSum)4GDK    4GDL    4NAW    4TQ0    5D7G   
PDB (IMB)4GDK    4GDL    4NAW    4TQ0    5D7G   
PDB (RSDB)4GDK    4GDL    4NAW    4TQ0    5D7G   
Structural Biology KnowledgeBase4GDK    4GDL    4NAW    4TQ0    5D7G   
SCOP (Structural Classification of Proteins)4GDK    4GDL    4NAW    4TQ0    5D7G   
CATH (Classification of proteins structures)4GDK    4GDL    4NAW    4TQ0    5D7G   
SuperfamilyQ676U5
Human Protein AtlasENSG00000085978
Peptide AtlasQ676U5
HPRD16498
IPIIPI00470446   IPI00555905   IPI00432751   IPI00446614   IPI00178692   IPI00871602   IPI00979030   IPI00797150   IPI00965758   IPI00790974   IPI00789327   IPI00917324   
Protein Interaction databases
DIP (DOE-UCLA)Q676U5
IntAct (EBI)Q676U5
FunCoupENSG00000085978
BioGRIDATG16L1
STRING (EMBL)ATG16L1
ZODIACATG16L1
Ontologies - Pathways
QuickGOQ676U5
Ontology : AmiGOautophagosome assembly  autophagosome assembly  autophagosome membrane  protein binding  autophagosome  cytosol  axoneme  protein transport  macroautophagy  ubiquitin-like protein transferase activity  pre-autophagosomal structure membrane  negative stranded viral RNA replication  identical protein binding  protein homooligomerization  
Ontology : EGO-EBIautophagosome assembly  autophagosome assembly  autophagosome membrane  protein binding  autophagosome  cytosol  axoneme  protein transport  macroautophagy  ubiquitin-like protein transferase activity  pre-autophagosomal structure membrane  negative stranded viral RNA replication  identical protein binding  protein homooligomerization  
Pathways : KEGGRegulation of autophagy   
NDEx NetworkATG16L1
Atlas of Cancer Signalling NetworkATG16L1
Wikipedia pathwaysATG16L1
Orthology - Evolution
OrthoDB55054
GeneTree (enSembl)ENSG00000085978
Phylogenetic Trees/Animal Genes : TreeFamATG16L1
HOVERGENQ676U5
HOGENOMQ676U5
Homologs : HomoloGeneATG16L1
Homology/Alignments : Family Browser (UCSC)ATG16L1
Gene fusions - Rearrangements
Fusion : MitelmanDGKD/ATG16L1 [2q37.1/2q37.1]  [t(2;2)(q37;q37)]  
Fusion: TCGADGKD 2q37.1 ATG16L1 2q37.1 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATG16L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATG16L1
dbVarATG16L1
ClinVarATG16L1
1000_GenomesATG16L1 
Exome Variant ServerATG16L1
ExAC (Exome Aggregation Consortium)ATG16L1 (select the gene name)
Genetic variants : HAPMAP55054
Genomic Variants (DGV)ATG16L1 [DGVbeta]
DECIPHERATG16L1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATG16L1 
Mutations
ICGC Data PortalATG16L1 
TCGA Data PortalATG16L1 
Broad Tumor PortalATG16L1
OASIS PortalATG16L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATG16L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATG16L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATG16L1
DgiDB (Drug Gene Interaction Database)ATG16L1
DoCM (Curated mutations)ATG16L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATG16L1 (select a term)
intoGenATG16L1
Cancer3DATG16L1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610767    611081   
Orphanet
MedgenATG16L1
Genetic Testing Registry ATG16L1
NextProtQ676U5 [Medical]
TSGene55054
GENETestsATG16L1
Target ValidationATG16L1
Huge Navigator ATG16L1 [HugePedia]
snp3D : Map Gene to Disease55054
BioCentury BCIQATG16L1
ClinGenATG16L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55054
Chemical/Pharm GKB GenePA134902949
Clinical trialATG16L1
Miscellaneous
canSAR (ICR)ATG16L1 (select the gene name)
Probes
Litterature
PubMed159 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATG16L1
EVEXATG16L1
GoPubMedATG16L1
iHOPATG16L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:55:37 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.