Identity
HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
APG16L,ATG16A,ATG16L,IBD10,WDR30
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55054
MIM: 610767
HGNC: 21498
Ensembl: ENSG00000085978
Variants:
dbSNP: 55054
ClinVar: 55054
TCGA: ENSG00000085978
COSMIC: ATG16L1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10004 | adalimumab | Chemical | ClinicalAnnotation | associated | PD | 25712183 | |
| PA443815 | Crohn Disease | Disease | ClinicalAnnotation | associated | PD | 25712183 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37837511 | 2024 | ATG16L1 rs2241880/T300A increases susceptibility to perianal Crohn's disease: An updated meta-analysis on inflammatory bowel disease risk and clinical outcomes. | 2 |
| 37991129 | 2024 | Association of ATG16L1 and ATG5 gene polymorphisms with susceptibility to hepatitis B virus infection and progression to HCC in central China. | 0 |
| 38227290 | 2024 | The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response. | 2 |
| 38281293 | 2024 | Association of ATG10 rs1864183, ATG16L1 rs2241880 and miR-126 with esophageal cancer. | 0 |
| 38548722 | 2024 | Autophagy-enhancing ATG16L1 polymorphism is associated with improved clinical outcome and T-cell immunity in chronic HIV-1 infection. | 1 |
| 38994020 | 2024 | Lens autophagy protein ATG16L1: a potential target for cataract treatment. | 0 |
| 37837511 | 2024 | ATG16L1 rs2241880/T300A increases susceptibility to perianal Crohn's disease: An updated meta-analysis on inflammatory bowel disease risk and clinical outcomes. | 2 |
| 37991129 | 2024 | Association of ATG16L1 and ATG5 gene polymorphisms with susceptibility to hepatitis B virus infection and progression to HCC in central China. | 0 |
| 38227290 | 2024 | The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response. | 2 |
| 38281293 | 2024 | Association of ATG10 rs1864183, ATG16L1 rs2241880 and miR-126 with esophageal cancer. | 0 |
| 38548722 | 2024 | Autophagy-enhancing ATG16L1 polymorphism is associated with improved clinical outcome and T-cell immunity in chronic HIV-1 infection. | 1 |
| 38994020 | 2024 | Lens autophagy protein ATG16L1: a potential target for cataract treatment. | 0 |
| 36804832 | 2023 | Association of PNPLA3 (rs738409) & TM6SF2 (rs58542926) and ATG16L1 (rs2241880) genetic variants with susceptibility to hepatocellular carcinoma in a group of Egyptian patients with HCV-induced liver cirrhosis. | 0 |
| 36958426 | 2023 | Detection of rare genetic variations in the promoter regions of the ATG16L gene in Parkinson's patients. | 1 |
| 37312743 | 2023 | Genetic Polymorphisms of NOD2 and ATG16L1 in Different Types of Digestive Tract Inflammation. | 0 |
Citation
Dessen P
ATG16L1 (autophagy related 16 like 1)
Atlas Genet Cytogenet Oncol Haematol. 2012-09-01
Online version: http://atlasgeneticsoncology.org/gene/52882/atg16l1
