Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ATG16L2 (autophagy related 16 like 2)

Identity

Alias_namesATG16 autophagy related 16-like 2 (S. cerevisiae)
autophagy related 16-like 2 (S. cerevisiae)
Alias_symbol (synonym)FLJ00012
WDR80
ATG16B
Other alias
HGNC (Hugo) ATG16L2
LocusID (NCBI) 89849
Atlas_Id 54138
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 72814406 and ends at 72829635 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATG16L2 (11q13.4) / FCHSD2 (11q13.4)ATG16L2 (11q13.4) / KMT2A (11q23.3)ATG16L2 (11q13.4) / MAGI3 (1p13.2)
LRP5 (11q13.2) / ATG16L2 (11q13.4)ZWILCH (15q22.31) / ATG16L2 (11q13.4)LRP5 11q13.2 / ATG16L2 11q13.4
ZWILCH 15q22.31 / ATG16L2 11q13.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATG16L2   25464
Cards
Entrez_Gene (NCBI)ATG16L2  89849  autophagy related 16 like 2
AliasesATG16B; WDR80
GeneCards (Weizmann)ATG16L2
Ensembl hg19 (Hinxton)ENSG00000168010 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168010 [Gene_View]  chr11:72814406-72829635 [Contig_View]  ATG16L2 [Vega]
ICGC DataPortalENSG00000168010
TCGA cBioPortalATG16L2
AceView (NCBI)ATG16L2
Genatlas (Paris)ATG16L2
WikiGenes89849
SOURCE (Princeton)ATG16L2
Genetics Home Reference (NIH)ATG16L2
Genomic and cartography
GoldenPath hg38 (UCSC)ATG16L2  -     chr11:72814406-72829635 +  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATG16L2  -     11q13.4   [Description]    (hg19-Feb_2009)
EnsemblATG16L2 - 11q13.4 [CytoView hg19]  ATG16L2 - 11q13.4 [CytoView hg38]
Mapping of homologs : NCBIATG16L2 [Mapview hg19]  ATG16L2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK024423 AK090597 AK091151 AK093017 AK303270
RefSeq transcript (Entrez)NM_001318766 NM_033388
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATG16L2
Cluster EST : UnigeneHs.653186 [ NCBI ]
CGAP (NCI)Hs.653186
Alternative Splicing GalleryENSG00000168010
Gene ExpressionATG16L2 [ NCBI-GEO ]   ATG16L2 [ EBI - ARRAY_EXPRESS ]   ATG16L2 [ SEEK ]   ATG16L2 [ MEM ]
Gene Expression Viewer (FireBrowse)ATG16L2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)89849
GTEX Portal (Tissue expression)ATG16L2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NAA4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NAA4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NAA4
Splice isoforms : SwissVarQ8NAA4
PhosPhoSitePlusQ8NAA4
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)Autophagy-rel_prot_16    G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)ATG16 (PF08614)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam08614    pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)ATG16L2
DMDM Disease mutations89849
Blocks (Seattle)ATG16L2
SuperfamilyQ8NAA4
Human Protein AtlasENSG00000168010
Peptide AtlasQ8NAA4
HPRD10959
IPIIPI00300536   IPI00892538   IPI00892678   IPI01018893   IPI00025503   IPI00910495   IPI01015289   IPI01014051   IPI01012736   IPI01011698   IPI01013877   IPI01012652   IPI01011283   IPI01012052   IPI01012461   IPI01009443   
Protein Interaction databases
DIP (DOE-UCLA)Q8NAA4
IntAct (EBI)Q8NAA4
FunCoupENSG00000168010
BioGRIDATG16L2
STRING (EMBL)ATG16L2
ZODIACATG16L2
Ontologies - Pathways
QuickGOQ8NAA4
Ontology : AmiGOautophagosome assembly  autophagosome membrane  nucleoplasm  protein transport  negative stranded viral RNA replication  
Ontology : EGO-EBIautophagosome assembly  autophagosome membrane  nucleoplasm  protein transport  negative stranded viral RNA replication  
Pathways : KEGGRegulation of autophagy   
NDEx NetworkATG16L2
Atlas of Cancer Signalling NetworkATG16L2
Wikipedia pathwaysATG16L2
Orthology - Evolution
OrthoDB89849
GeneTree (enSembl)ENSG00000168010
Phylogenetic Trees/Animal Genes : TreeFamATG16L2
HOVERGENQ8NAA4
HOGENOMQ8NAA4
Homologs : HomoloGeneATG16L2
Homology/Alignments : Family Browser (UCSC)ATG16L2
Gene fusions - Rearrangements
Fusion : MitelmanLRP5/ATG16L2 [11q13.2/11q13.4]  [t(11;11)(q13;q13)]  
Fusion : MitelmanZWILCH/ATG16L2 [15q22.31/11q13.4]  [t(11;15)(q13;q22)]  
Fusion: TCGALRP5 11q13.2 ATG16L2 11q13.4 GBM
Fusion: TCGAZWILCH 15q22.31 ATG16L2 11q13.4 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATG16L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATG16L2
dbVarATG16L2
ClinVarATG16L2
1000_GenomesATG16L2 
Exome Variant ServerATG16L2
ExAC (Exome Aggregation Consortium)ATG16L2 (select the gene name)
Genetic variants : HAPMAP89849
Genomic Variants (DGV)ATG16L2 [DGVbeta]
DECIPHERATG16L2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATG16L2 
Mutations
ICGC Data PortalATG16L2 
TCGA Data PortalATG16L2 
Broad Tumor PortalATG16L2
OASIS PortalATG16L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATG16L2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATG16L2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATG16L2
DgiDB (Drug Gene Interaction Database)ATG16L2
DoCM (Curated mutations)ATG16L2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATG16L2 (select a term)
intoGenATG16L2
Cancer3DATG16L2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenATG16L2
Genetic Testing Registry ATG16L2
NextProtQ8NAA4 [Medical]
TSGene89849
GENETestsATG16L2
Huge Navigator ATG16L2 [HugePedia]
snp3D : Map Gene to Disease89849
BioCentury BCIQATG16L2
ClinGenATG16L2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD89849
Chemical/Pharm GKB GenePA142672575
Clinical trialATG16L2
Miscellaneous
canSAR (ICR)ATG16L2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATG16L2
EVEXATG16L2
GoPubMedATG16L2
iHOPATG16L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:07:01 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.