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ATG3 (autophagy related 3)

Identity

Alias_namesAPG3L
APG3 autophagy 3-like (S. cerevisiae)
ATG3 autophagy related 3 homolog (S. cerevisiae)
Alias_symbol (synonym)PC3-96
FLJ22125
MGC15201
DKFZp564M1178
Other aliasAPG3
APG3-LIKE
HGNC (Hugo) ATG3
LocusID (NCBI) 64422
Atlas_Id 60599
Location 3q13.2  [Link to chromosome band 3q13]
Location_base_pair Starts at 112532507 and ends at 112561963 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATG3 (3q13.2) / KCNIP4 (4p15.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATG3   20962
Cards
Entrez_Gene (NCBI)ATG3  64422  autophagy related 3
AliasesAPG3; APG3-LIKE; APG3L; PC3-96
GeneCards (Weizmann)ATG3
Ensembl hg19 (Hinxton)ENSG00000144848 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144848 [Gene_View]  chr3:112532507-112561963 [Contig_View]  ATG3 [Vega]
ICGC DataPortalENSG00000144848
TCGA cBioPortalATG3
AceView (NCBI)ATG3
Genatlas (Paris)ATG3
WikiGenes64422
SOURCE (Princeton)ATG3
Genetics Home Reference (NIH)ATG3
Genomic and cartography
GoldenPath hg38 (UCSC)ATG3  -     chr3:112532507-112561963 -  3q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATG3  -     3q13.2   [Description]    (hg19-Feb_2009)
EnsemblATG3 - 3q13.2 [CytoView hg19]  ATG3 - 3q13.2 [CytoView hg38]
Mapping of homologs : NCBIATG3 [Mapview hg19]  ATG3 [Mapview hg38]
OMIM609606   
Gene and transcription
Genbank (Entrez)AA448974 AB079384 AF202092 AK025778 AK123511
RefSeq transcript (Entrez)NM_001278712 NM_022488
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATG3
Cluster EST : UnigeneHs.477126 [ NCBI ]
CGAP (NCI)Hs.477126
Alternative Splicing GalleryENSG00000144848
Gene ExpressionATG3 [ NCBI-GEO ]   ATG3 [ EBI - ARRAY_EXPRESS ]   ATG3 [ SEEK ]   ATG3 [ MEM ]
Gene Expression Viewer (FireBrowse)ATG3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64422
GTEX Portal (Tissue expression)ATG3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NT62   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NT62  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NT62
Splice isoforms : SwissVarQ9NT62
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ9NT62
Domains : Interpro (EBI)Autophagy-rel_prot_3    Autophagy-rel_prot_3_C    Autophagy-rel_prot_3_N   
Domain families : Pfam (Sanger)Autophagy_act_C (PF03987)    Autophagy_C (PF10381)    Autophagy_N (PF03986)   
Domain families : Pfam (NCBI)pfam03987    pfam10381    pfam03986   
Conserved Domain (NCBI)ATG3
DMDM Disease mutations64422
Blocks (Seattle)ATG3
PDB (SRS)4NAW   
PDB (PDBSum)4NAW   
PDB (IMB)4NAW   
PDB (RSDB)4NAW   
Structural Biology KnowledgeBase4NAW   
SCOP (Structural Classification of Proteins)4NAW   
CATH (Classification of proteins structures)4NAW   
SuperfamilyQ9NT62
Human Protein AtlasENSG00000144848
Peptide AtlasQ9NT62
HPRD10654
IPIIPI00022254   IPI00449201   IPI00792840   IPI00946557   
Protein Interaction databases
DIP (DOE-UCLA)Q9NT62
IntAct (EBI)Q9NT62
FunCoupENSG00000144848
BioGRIDATG3
STRING (EMBL)ATG3
ZODIACATG3
Ontologies - Pathways
QuickGOQ9NT62
Ontology : AmiGOautophagosome assembly  autophagosome assembly  cytoplasmic ubiquitin ligase complex  mitophagy  protein binding  cytosol  cytosol  cellular protein modification process  protein targeting to membrane  macroautophagy  protein ubiquitination  ligase activity  Atg8 ligase activity  Atg8 ligase activity  Atg12 transferase activity  ubiquitin-like protein transferase activity  enzyme binding  mitochondrial fragmentation involved in apoptotic process  nucleophagy  negative regulation of phagocytosis  regulation of cilium assembly  
Ontology : EGO-EBIautophagosome assembly  autophagosome assembly  cytoplasmic ubiquitin ligase complex  mitophagy  protein binding  cytosol  cytosol  cellular protein modification process  protein targeting to membrane  macroautophagy  protein ubiquitination  ligase activity  Atg8 ligase activity  Atg8 ligase activity  Atg12 transferase activity  ubiquitin-like protein transferase activity  enzyme binding  mitochondrial fragmentation involved in apoptotic process  nucleophagy  negative regulation of phagocytosis  regulation of cilium assembly  
Pathways : KEGGRegulation of autophagy   
NDEx NetworkATG3
Atlas of Cancer Signalling NetworkATG3
Wikipedia pathwaysATG3
Orthology - Evolution
OrthoDB64422
GeneTree (enSembl)ENSG00000144848
Phylogenetic Trees/Animal Genes : TreeFamATG3
HOVERGENQ9NT62
HOGENOMQ9NT62
Homologs : HomoloGeneATG3
Homology/Alignments : Family Browser (UCSC)ATG3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATG3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATG3
dbVarATG3
ClinVarATG3
1000_GenomesATG3 
Exome Variant ServerATG3
ExAC (Exome Aggregation Consortium)ATG3 (select the gene name)
Genetic variants : HAPMAP64422
Genomic Variants (DGV)ATG3 [DGVbeta]
DECIPHERATG3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATG3 
Mutations
ICGC Data PortalATG3 
TCGA Data PortalATG3 
Broad Tumor PortalATG3
OASIS PortalATG3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATG3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATG3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATG3
DgiDB (Drug Gene Interaction Database)ATG3
DoCM (Curated mutations)ATG3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATG3 (select a term)
intoGenATG3
Cancer3DATG3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609606   
Orphanet
MedgenATG3
Genetic Testing Registry ATG3
NextProtQ9NT62 [Medical]
TSGene64422
GENETestsATG3
Target ValidationATG3
Huge Navigator ATG3 [HugePedia]
snp3D : Map Gene to Disease64422
BioCentury BCIQATG3
ClinGenATG3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64422
Chemical/Pharm GKB GenePA134883444
Clinical trialATG3
Miscellaneous
canSAR (ICR)ATG3 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATG3
EVEXATG3
GoPubMedATG3
iHOPATG3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:01:57 CEST 2017

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