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ATG7 (autophagy related 7)

Identity

Alias_namesAPG7L
APG7 autophagy 7-like (S. cerevisiae)
ATG7 autophagy related 7 homolog (S. cerevisiae)
Alias_symbol (synonym)GSA7
DKFZp434N0735
Other aliasAPG7-LIKE
HGNC (Hugo) ATG7
LocusID (NCBI) 10533
Atlas_Id 53558
Location 3p25.3  [Link to chromosome band 3p25]
Location_base_pair Starts at 11314010 and ends at 11599139 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATG7 (3p25.3) / ATG7 (3p25.3)ATG7 (3p25.3) / BRAF (7q34)ATG7 (3p25.3) / GNB2 (7q22.1)
ATG7 (3p25.3) / PPARG (3p25.2)ATG7 (3p25.3) / SKAP2 (7p15.2)ATG7 (3p25.3) / SLC9A9 (3q24)
BRAF (7q34) / ATG7 (3p25.3)FYCO1 (3p21.31) / ATG7 (3p25.3)LLPH (12q14.3) / ATG7 (3p25.3)
MYCBP2 (13q22.3) / ATG7 (3p25.3)SETD5 (3p25.3) / ATG7 (3p25.3)VGLL4 (3p25.3) / ATG7 (3p25.3)
ZNF407 (18q22.3) / ATG7 (3p25.3)ATG7 3p25.3 / BRAF 7q34ATG7 3p25.3 / PPARG 3p25.2
BRAF 7q34 / ATG7 3p25.3FYCO1 3p21.31 / ATG7 3p25.3SETD5 3p25.3 / ATG7 3p25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATG7   16935
Cards
Entrez_Gene (NCBI)ATG7  10533  autophagy related 7
AliasesAPG7-LIKE; APG7L; GSA7
GeneCards (Weizmann)ATG7
Ensembl hg19 (Hinxton)ENSG00000197548 [Gene_View]  chr3:11314010-11599139 [Contig_View]  ATG7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000197548 [Gene_View]  chr3:11314010-11599139 [Contig_View]  ATG7 [Vega]
ICGC DataPortalENSG00000197548
TCGA cBioPortalATG7
AceView (NCBI)ATG7
Genatlas (Paris)ATG7
WikiGenes10533
SOURCE (Princeton)ATG7
Genetics Home Reference (NIH)ATG7
Genomic and cartography
GoldenPath hg19 (UCSC)ATG7  -     chr3:11314010-11599139 +  3p25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ATG7  -     3p25.3   [Description]    (hg38-Dec_2013)
EnsemblATG7 - 3p25.3 [CytoView hg19]  ATG7 - 3p25.3 [CytoView hg38]
Mapping of homologs : NCBIATG7 [Mapview hg19]  ATG7 [Mapview hg38]
OMIM608760   
Gene and transcription
Genbank (Entrez)AF094516 AK075221 AK298833 AK303694 AK314504
RefSeq transcript (Entrez)NM_001136031 NM_001144912 NM_006395
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)ATG7
Cluster EST : UnigeneHs.38032 [ NCBI ]
CGAP (NCI)Hs.38032
Alternative Splicing GalleryENSG00000197548
Gene ExpressionATG7 [ NCBI-GEO ]   ATG7 [ EBI - ARRAY_EXPRESS ]   ATG7 [ SEEK ]   ATG7 [ MEM ]
Gene Expression Viewer (FireBrowse)ATG7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10533
GTEX Portal (Tissue expression)ATG7
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95352   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95352  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95352
Splice isoforms : SwissVarO95352
PhosPhoSitePlusO95352
Domains : Interpro (EBI)Atg7    Atg7_N    NAD(P)-bd_dom    ThiF_NAD_FAD-bd   
Domain families : Pfam (Sanger)ATG7_N (PF16420)    ThiF (PF00899)   
Domain families : Pfam (NCBI)pfam16420    pfam00899   
Conserved Domain (NCBI)ATG7
DMDM Disease mutations10533
Blocks (Seattle)ATG7
SuperfamilyO95352
Human Protein AtlasENSG00000197548
Peptide AtlasO95352
HPRD12293
IPIIPI00007404   IPI00479911   IPI00925029   IPI00909500   IPI00926490   IPI00926766   IPI00926965   IPI00925593   IPI00924928   IPI00926067   IPI00925374   IPI00924557   IPI00924785   IPI00925219   IPI00926888   
Protein Interaction databases
DIP (DOE-UCLA)O95352
IntAct (EBI)O95352
FunCoupENSG00000197548
BioGRIDATG7
STRING (EMBL)ATG7
ZODIACATG7
Ontologies - Pathways
QuickGOO95352
Ontology : AmiGOpre-autophagosomal structure  ubiquitin activating enzyme activity  protein binding  cytoplasm  cytosol  cytosol  axoneme  cellular protein modification process  protein lipidation  C-terminal protein lipidation  cellular response to nitrogen starvation  transcription factor binding  cellular response to starvation  positive regulation of autophagy  protein transport  macroautophagy  positive regulation of macroautophagy  protein ubiquitination  Atg12 activating enzyme activity  Atg12 activating enzyme activity  Atg8 activating enzyme activity  positive regulation of protein modification process  piecemeal microautophagy of nucleus  suppression by virus of host autophagy  protein homodimerization activity  positive regulation of apoptotic process  late nucleophagy  positive regulation of protein catabolic process  defense response to virus  membrane fusion  cellular response to hyperoxia  regulation of mitophagy  
Ontology : EGO-EBIpre-autophagosomal structure  ubiquitin activating enzyme activity  protein binding  cytoplasm  cytosol  cytosol  axoneme  cellular protein modification process  protein lipidation  C-terminal protein lipidation  cellular response to nitrogen starvation  transcription factor binding  cellular response to starvation  positive regulation of autophagy  protein transport  macroautophagy  positive regulation of macroautophagy  protein ubiquitination  Atg12 activating enzyme activity  Atg12 activating enzyme activity  Atg8 activating enzyme activity  positive regulation of protein modification process  piecemeal microautophagy of nucleus  suppression by virus of host autophagy  protein homodimerization activity  positive regulation of apoptotic process  late nucleophagy  positive regulation of protein catabolic process  defense response to virus  membrane fusion  cellular response to hyperoxia  regulation of mitophagy  
Pathways : KEGGRegulation of autophagy   
NDEx NetworkATG7
Atlas of Cancer Signalling NetworkATG7
Wikipedia pathwaysATG7
Orthology - Evolution
OrthoDB10533
GeneTree (enSembl)ENSG00000197548
Phylogenetic Trees/Animal Genes : TreeFamATG7
HOVERGENO95352
HOGENOMO95352
Homologs : HomoloGeneATG7
Homology/Alignments : Family Browser (UCSC)ATG7
Gene fusions - Rearrangements
Fusion : MitelmanATG7/BRAF [3p25.3/7q34]  
Fusion : MitelmanATG7/PPARG [3p25.3/3p25.2]  [t(3;3)(p25;p25)]  
Fusion : MitelmanBRAF/ATG7 [7q34/3p25.3]  [t(3;7)(p25;q34)]  
Fusion : MitelmanFYCO1/ATG7 [3p21.31/3p25.3]  [t(3;3)(p21;p25)]  
Fusion : MitelmanSETD5/ATG7 [3p25.3/3p25.3]  [t(3;3)(p25;p25)]  
Fusion: TCGAATG7 3p25.3 BRAF 7q34 SKCM
Fusion: TCGAATG7 3p25.3 PPARG 3p25.2 LGG
Fusion: TCGABRAF 7q34 ATG7 3p25.3 SKCM
Fusion: TCGAFYCO1 3p21.31 ATG7 3p25.3 LUAD
Fusion: TCGASETD5 3p25.3 ATG7 3p25.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATG7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATG7
dbVarATG7
ClinVarATG7
1000_GenomesATG7 
Exome Variant ServerATG7
ExAC (Exome Aggregation Consortium)ATG7 (select the gene name)
Genetic variants : HAPMAP10533
Genomic Variants (DGV)ATG7 [DGVbeta]
DECIPHER (Syndromes)3:11314010-11599139  ENSG00000197548
CONAN: Copy Number AnalysisATG7 
Mutations
ICGC Data PortalATG7 
TCGA Data PortalATG7 
Broad Tumor PortalATG7
OASIS PortalATG7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATG7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATG7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATG7
DgiDB (Drug Gene Interaction Database)ATG7
DoCM (Curated mutations)ATG7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATG7 (select a term)
intoGenATG7
Cancer3DATG7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608760   
Orphanet
MedgenATG7
Genetic Testing Registry ATG7
NextProtO95352 [Medical]
TSGene10533
GENETestsATG7
Huge Navigator ATG7 [HugePedia]
snp3D : Map Gene to Disease10533
BioCentury BCIQATG7
ClinGenATG7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10533
Chemical/Pharm GKB GenePA134983397
Clinical trialATG7
Miscellaneous
canSAR (ICR)ATG7 (select the gene name)
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATG7
EVEXATG7
GoPubMedATG7
iHOPATG7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:56:51 CET 2017

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