Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ATL2 (atlastin GTPase 2)

Identity

Alias_namesARL6IP2
ADP-ribosylation factor-like 6 interacting protein 2
Other aliasARL3IP2
aip-2
atlastin2
HGNC (Hugo) ATL2
LocusID (NCBI) 64225
Atlas_Id 56268
Location 2p22.2  [Link to chromosome band 2p22]
Location_base_pair Starts at 38293957 and ends at 38377423 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATL2 (2p22.2) / ATL2 (2p22.2)ATL2 (2p22.2) / DHX57 (2p22.1)ATL2 (2p22.2) / HNRNPLL (2p22.1)
ATL2 (2p22.2) / NDRG2 (14q11.2)C9orf114 (9q34.11) / ATL2 (2p22.2)LDB2 (4p15.32) / ATL2 (2p22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATL2   24047
Cards
Entrez_Gene (NCBI)ATL2  64225  atlastin GTPase 2
AliasesARL3IP2; ARL6IP2; aip-2; atlastin2
GeneCards (Weizmann)ATL2
Ensembl hg19 (Hinxton)ENSG00000119787 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119787 [Gene_View]  chr2:38293957-38377423 [Contig_View]  ATL2 [Vega]
ICGC DataPortalENSG00000119787
TCGA cBioPortalATL2
AceView (NCBI)ATL2
Genatlas (Paris)ATL2
WikiGenes64225
SOURCE (Princeton)ATL2
Genetics Home Reference (NIH)ATL2
Genomic and cartography
GoldenPath hg38 (UCSC)ATL2  -     chr2:38293957-38377423 -  2p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATL2  -     2p22.2   [Description]    (hg19-Feb_2009)
EnsemblATL2 - 2p22.2 [CytoView hg19]  ATL2 - 2p22.2 [CytoView hg38]
Mapping of homologs : NCBIATL2 [Mapview hg19]  ATL2 [Mapview hg38]
OMIM609368   
Gene and transcription
Genbank (Entrez)AI630457 AK026946 AK124434 AK225190 AK294049
RefSeq transcript (Entrez)NM_001135673 NM_001308076 NM_001330458 NM_001330459 NM_001330460 NM_001330461 NM_001330462 NM_001330463 NM_001330464 NM_022374
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATL2
Cluster EST : UnigeneHs.727652 [ NCBI ]
CGAP (NCI)Hs.727652
Alternative Splicing GalleryENSG00000119787
Gene ExpressionATL2 [ NCBI-GEO ]   ATL2 [ EBI - ARRAY_EXPRESS ]   ATL2 [ SEEK ]   ATL2 [ MEM ]
Gene Expression Viewer (FireBrowse)ATL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64225
GTEX Portal (Tissue expression)ATL2
Human Protein AtlasENSG00000119787-ATL2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NHH9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NHH9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NHH9
Splice isoforms : SwissVarQ8NHH9
Catalytic activity : Enzyme3.6.5.- [ Enzyme-Expasy ]   3.6.5.-3.6.5.- [ IntEnz-EBI ]   3.6.5.- [ BRENDA ]   3.6.5.- [ KEGG ]   
PhosPhoSitePlusQ8NHH9
Domaine pattern : Prosite (Expaxy)G_GB1_RHD3 (PS51715)   
Domains : Interpro (EBI)G_GB1_RHD3_dom    Guanylate-bd_C    Guanylate-bd_N    P-loop_NTPase   
Domain families : Pfam (Sanger)GBP (PF02263)    GBP_C (PF02841)   
Domain families : Pfam (NCBI)pfam02263    pfam02841   
Conserved Domain (NCBI)ATL2
DMDM Disease mutations64225
Blocks (Seattle)ATL2
SuperfamilyQ8NHH9
Human Protein Atlas [tissue]ENSG00000119787-ATL2 [tissue]
Peptide AtlasQ8NHH9
HPRD10662
IPIIPI00169267   IPI00007183   IPI00845387   IPI01014314   IPI00894415   IPI00893779   IPI00894553   IPI00917150   IPI00916674   IPI00917814   IPI00917944   IPI00917688   
Protein Interaction databases
DIP (DOE-UCLA)Q8NHH9
IntAct (EBI)Q8NHH9
FunCoupENSG00000119787
BioGRIDATL2
STRING (EMBL)ATL2
ZODIACATL2
Ontologies - Pathways
QuickGOQ8NHH9
Ontology : AmiGOGTPase activity  protein binding  GTP binding  endoplasmic reticulum  endoplasmic reticulum membrane  ER to Golgi vesicle-mediated transport  endoplasmic reticulum organization  Golgi organization  membrane  integral component of membrane  identical protein binding  protein homooligomerization  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  endoplasmic reticulum  endoplasmic reticulum membrane  ER to Golgi vesicle-mediated transport  endoplasmic reticulum organization  Golgi organization  membrane  integral component of membrane  identical protein binding  protein homooligomerization  
NDEx NetworkATL2
Atlas of Cancer Signalling NetworkATL2
Wikipedia pathwaysATL2
Orthology - Evolution
OrthoDB64225
GeneTree (enSembl)ENSG00000119787
Phylogenetic Trees/Animal Genes : TreeFamATL2
HOVERGENQ8NHH9
HOGENOMQ8NHH9
Homologs : HomoloGeneATL2
Homology/Alignments : Family Browser (UCSC)ATL2
Gene fusions - Rearrangements
Tumor Fusion PortalATL2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATL2
dbVarATL2
ClinVarATL2
1000_GenomesATL2 
Exome Variant ServerATL2
ExAC (Exome Aggregation Consortium)ENSG00000119787
GNOMAD BrowserENSG00000119787
Genetic variants : HAPMAP64225
Genomic Variants (DGV)ATL2 [DGVbeta]
DECIPHERATL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATL2 
Mutations
ICGC Data PortalATL2 
TCGA Data PortalATL2 
Broad Tumor PortalATL2
OASIS PortalATL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATL2
DgiDB (Drug Gene Interaction Database)ATL2
DoCM (Curated mutations)ATL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATL2 (select a term)
intoGenATL2
Cancer3DATL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609368   
Orphanet
DisGeNETATL2
MedgenATL2
Genetic Testing Registry ATL2
NextProtQ8NHH9 [Medical]
TSGene64225
GENETestsATL2
Target ValidationATL2
Huge Navigator ATL2 [HugePedia]
snp3D : Map Gene to Disease64225
BioCentury BCIQATL2
ClinGenATL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64225
Chemical/Pharm GKB GenePA164716322
Clinical trialATL2
Miscellaneous
canSAR (ICR)ATL2 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATL2
EVEXATL2
GoPubMedATL2
iHOPATL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:04:06 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.