ATL2 (atlastin GTPase 2)

2016-10-01  

Identity

HGNC
ATL2
LOCATION
2p22.2
LOCUSID
64225
ALIAS
ARL3IP2,ARL6IP2,aip-2,atlastin2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 64225
MIM: 609368
HGNC: 24047
Ensembl: ENSG00000119787

Variants:

dbSNP: 64225
ClinVar: 64225
TCGA: ENSG00000119787
COSMIC: ATL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119787ENST00000378954Q8NHH9
ENSG00000119787ENST00000402054Q8NHH9
ENSG00000119787ENST00000405384F8WD17
ENSG00000119787ENST00000406122B5MCN0
ENSG00000119787ENST00000416222F8WBH0
ENSG00000119787ENST00000419554Q8NHH9
ENSG00000119787ENST00000443098H7C3A2
ENSG00000119787ENST00000449130C9JQQ5
ENSG00000119787ENST00000451483C9JC25
ENSG00000119787ENST00000452935Q8NHH9
ENSG00000119787ENST00000456736F8WEN4
ENSG00000119787ENST00000629272B5MCN0
ENSG00000119787ENST00000651368Q8NHH9

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
182702072008Atlastin GTPases are required for Golgi apparatus and ER morphogenesis.78
220656362011An intramolecular salt bridge drives the soluble domain of GTP-bound atlastin into the postfusion conformation.14
257732772015Human atlastin GTPases mediate differentiated fusion of endoplasmic reticulum membranes.12

Citation

Dessen P

ATL2 (atlastin GTPase 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56268/atl2