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ATL3 (atlastin GTPase 3)

Identity

Alias_symbol (synonym)DKFZP564J0863
Other aliasHSN1F
HGNC (Hugo) ATL3
LocusID (NCBI) 25923
Atlas_Id 56067
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 63624082 and ends at 63671730 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATL3 (11q12.3) / ZDHHC14 (6q25.3)SOX2-OT (3q26.33) / ATL3 (11q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(3;11)(q26;q13) SOX2-OT/ATL3
t(6;11)(q25;q13) ATL3/ZDHHC14


External links

Nomenclature
HGNC (Hugo)ATL3   24526
Cards
Entrez_Gene (NCBI)ATL3  25923  atlastin GTPase 3
AliasesHSN1F
GeneCards (Weizmann)ATL3
Ensembl hg19 (Hinxton)ENSG00000184743 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184743 [Gene_View]  ENSG00000184743 [Sequence]  chr11:63624082-63671730 [Contig_View]  ATL3 [Vega]
ICGC DataPortalENSG00000184743
TCGA cBioPortalATL3
AceView (NCBI)ATL3
Genatlas (Paris)ATL3
WikiGenes25923
SOURCE (Princeton)ATL3
Genetics Home Reference (NIH)ATL3
Genomic and cartography
GoldenPath hg38 (UCSC)ATL3  -     chr11:63624082-63671730 -  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATL3  -     11q13.1   [Description]    (hg19-Feb_2009)
ATL3 - 11q13.1 [CytoView hg19]  ATL3 - 11q13.1 [CytoView hg38]
Mapping of homologs : NCBIATL3 [Mapview hg19]  ATL3 [Mapview hg38]
OMIM609369   615632   
Gene and transcription
Genbank (Entrez)AK023383 AK090822 AK094227 AK097588 AK301910
RefSeq transcript (Entrez)NM_001290048 NM_015459
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATL3
Cluster EST : UnigeneHs.356719 [ NCBI ]
CGAP (NCI)Hs.356719
Alternative Splicing GalleryENSG00000184743
Gene ExpressionATL3 [ NCBI-GEO ]   ATL3 [ EBI - ARRAY_EXPRESS ]   ATL3 [ SEEK ]   ATL3 [ MEM ]
Gene Expression Viewer (FireBrowse)ATL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25923
GTEX Portal (Tissue expression)ATL3
Human Protein AtlasENSG00000184743-ATL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6DD88   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6DD88  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6DD88
Splice isoforms : SwissVarQ6DD88
PhosPhoSitePlusQ6DD88
Domaine pattern : Prosite (Expaxy)G_GB1_RHD3 (PS51715)   
Domains : Interpro (EBI)G_GB1_RHD3_dom    Guanylate-bd/ATL_C    Guanylate-bd_C_sf    Guanylate-bd_N    P-loop_NTPase   
Domain families : Pfam (Sanger)GBP (PF02263)    GBP_C (PF02841)   
Domain families : Pfam (NCBI)pfam02263    pfam02841   
Conserved Domain (NCBI)ATL3
DMDM Disease mutations25923
Blocks (Seattle)ATL3
PDB (RSDB)5VGR   
PDB Europe5VGR   
PDB (PDBSum)5VGR   
PDB (IMB)5VGR   
Structural Biology KnowledgeBase5VGR   
SCOP (Structural Classification of Proteins)5VGR   
CATH (Classification of proteins structures)5VGR   
SuperfamilyQ6DD88
Human Protein Atlas [tissue]ENSG00000184743-ATL3 [tissue]
Peptide AtlasQ6DD88
HPRD13170
IPIIPI00550523   IPI00845461   IPI01012574   IPI01012170   
Protein Interaction databases
DIP (DOE-UCLA)Q6DD88
IntAct (EBI)Q6DD88
FunCoupENSG00000184743
BioGRIDATL3
STRING (EMBL)ATL3
ZODIACATL3
Ontologies - Pathways
QuickGOQ6DD88
Ontology : AmiGOGTPase activity  protein binding  GTP binding  endoplasmic reticulum  ER to Golgi vesicle-mediated transport  endoplasmic reticulum organization  Golgi organization  membrane  integral component of membrane  identical protein binding  protein homooligomerization  endoplasmic reticulum tubular network  endoplasmic reticulum tubular network membrane  positive regulation of endoplasmic reticulum tubular network organization  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  endoplasmic reticulum  ER to Golgi vesicle-mediated transport  endoplasmic reticulum organization  Golgi organization  membrane  integral component of membrane  identical protein binding  protein homooligomerization  endoplasmic reticulum tubular network  endoplasmic reticulum tubular network membrane  positive regulation of endoplasmic reticulum tubular network organization  
NDEx NetworkATL3
Atlas of Cancer Signalling NetworkATL3
Wikipedia pathwaysATL3
Orthology - Evolution
OrthoDB25923
GeneTree (enSembl)ENSG00000184743
Phylogenetic Trees/Animal Genes : TreeFamATL3
HOGENOMQ6DD88
Homologs : HomoloGeneATL3
Homology/Alignments : Family Browser (UCSC)ATL3
Gene fusions - Rearrangements
Fusion : QuiverATL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATL3
dbVarATL3
ClinVarATL3
1000_GenomesATL3 
Exome Variant ServerATL3
ExAC (Exome Aggregation Consortium)ENSG00000184743
GNOMAD BrowserENSG00000184743
Varsome BrowserATL3
Genetic variants : HAPMAP25923
Genomic Variants (DGV)ATL3 [DGVbeta]
DECIPHERATL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATL3 
Mutations
ICGC Data PortalATL3 
TCGA Data PortalATL3 
Broad Tumor PortalATL3
OASIS PortalATL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATL3
DgiDB (Drug Gene Interaction Database)ATL3
DoCM (Curated mutations)ATL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATL3 (select a term)
intoGenATL3
Cancer3DATL3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609369    615632   
Orphanet10423   
DisGeNETATL3
MedgenATL3
Genetic Testing Registry ATL3
NextProtQ6DD88 [Medical]
TSGene25923
GENETestsATL3
Target ValidationATL3
Huge Navigator ATL3 [HugePedia]
snp3D : Map Gene to Disease25923
BioCentury BCIQATL3
ClinGenATL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25923
Chemical/Pharm GKB GenePA164716353
Clinical trialATL3
Miscellaneous
canSAR (ICR)ATL3 (select the gene name)
DataMed IndexATL3
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATL3
EVEXATL3
GoPubMedATL3
iHOPATL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 21 15:37:04 CET 2019

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