ATOH8 (atonal bHLH transcription factor 8)

2016-01-01 Affiliation

Identity

HGNC

ATOH8

LOCATION

2p11.2

LOCUSID

84913

ALIAS

HATH6,bHLHa21

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 84913
HGNC: 24126
Ensembl: ENSG00000168874

Variants:

dbSNP: 84913
ClinVar: 84913
TCGA: ENSG00000168874
COSMIC: ATOH8

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000168874	ENST00000306279	Q96SQ7

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
26099525	2015	Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells.	16
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	11
21857980	2011	Diversification and molecular evolution of ATOH8, a gene encoding a bHLH transcription factor.	9
25514850	2015	ATOH8: a novel marker in human muscle fiber regeneration.	8
30786928	2019	Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2-mediated ATOH8 transcriptional repression.	8
27049918	2016	Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma.	7
26496921	2016	A novel interaction between ATOH8 and PPP3CB.	3
28393252	2017	High expression of atonal homolog 8 predicts a poor clinical outcome in patients with colorectal cancer and contributes to tumor progression.	3

Citation

Dessen P

ATOH8 (atonal bHLH transcription factor 8)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55590/atoh8