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ATOH8 (atonal bHLH transcription factor 8)

Identity

Alias_namesatonal homolog 8 (Drosophila)
atonal homolog bHLH transcription factor 8
Alias_symbol (synonym)HATH6
FLJ14708
bHLHa21
Other alias
HGNC (Hugo) ATOH8
LocusID (NCBI) 84913
Atlas_Id 55590
Location 2p11.2  [Link to chromosome band 2p11]
Location_base_pair Starts at 85753786 and ends at 85791383 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATOH8 (2p11.2) / GNLY (2p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATOH8   24126
Cards
Entrez_Gene (NCBI)ATOH8  84913  atonal bHLH transcription factor 8
AliasesHATH6; bHLHa21
GeneCards (Weizmann)ATOH8
Ensembl hg19 (Hinxton)ENSG00000168874 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168874 [Gene_View]  chr2:85753786-85791383 [Contig_View]  ATOH8 [Vega]
ICGC DataPortalENSG00000168874
TCGA cBioPortalATOH8
AceView (NCBI)ATOH8
Genatlas (Paris)ATOH8
WikiGenes84913
SOURCE (Princeton)ATOH8
Genetics Home Reference (NIH)ATOH8
Genomic and cartography
GoldenPath hg38 (UCSC)ATOH8  -     chr2:85753786-85791383 +  2p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATOH8  -     2p11.2   [Description]    (hg19-Feb_2009)
EnsemblATOH8 - 2p11.2 [CytoView hg19]  ATOH8 - 2p11.2 [CytoView hg38]
Mapping of homologs : NCBIATOH8 [Mapview hg19]  ATOH8 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF529205 AK027614 AK074681 AK093766 AK096049
RefSeq transcript (Entrez)NM_032827
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATOH8
Cluster EST : UnigeneHs.135569 [ NCBI ]
CGAP (NCI)Hs.135569
Alternative Splicing GalleryENSG00000168874
Gene ExpressionATOH8 [ NCBI-GEO ]   ATOH8 [ EBI - ARRAY_EXPRESS ]   ATOH8 [ SEEK ]   ATOH8 [ MEM ]
Gene Expression Viewer (FireBrowse)ATOH8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84913
GTEX Portal (Tissue expression)ATOH8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96SQ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96SQ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96SQ7
Splice isoforms : SwissVarQ96SQ7
PhosPhoSitePlusQ96SQ7
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)ATOH8    bHLH_dom   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)ATOH8
DMDM Disease mutations84913
Blocks (Seattle)ATOH8
SuperfamilyQ96SQ7
Human Protein AtlasENSG00000168874
Peptide AtlasQ96SQ7
HPRD09813
IPIIPI00045865   IPI00470409   
Protein Interaction databases
DIP (DOE-UCLA)Q96SQ7
IntAct (EBI)Q96SQ7
FunCoupENSG00000168874
BioGRIDATOH8
STRING (EMBL)ATOH8
ZODIACATOH8
Ontologies - Pathways
QuickGOQ96SQ7
Ontology : AmiGOformation of primary germ layer  negative regulation of endothelial cell proliferation  transcription factor activity, sequence-specific DNA binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  nervous system development  positive regulation of endothelial cell migration  nuclear speck  cell differentiation  activating transcription factor binding  tube formation  positive regulation of endothelial cell differentiation  positive regulation of endothelial cell differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  protein dimerization activity  myoblast proliferation  SMAD protein signal transduction  E-box binding  
Ontology : EGO-EBIformation of primary germ layer  negative regulation of endothelial cell proliferation  transcription factor activity, sequence-specific DNA binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  nervous system development  positive regulation of endothelial cell migration  nuclear speck  cell differentiation  activating transcription factor binding  tube formation  positive regulation of endothelial cell differentiation  positive regulation of endothelial cell differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  protein dimerization activity  myoblast proliferation  SMAD protein signal transduction  E-box binding  
NDEx NetworkATOH8
Atlas of Cancer Signalling NetworkATOH8
Wikipedia pathwaysATOH8
Orthology - Evolution
OrthoDB84913
GeneTree (enSembl)ENSG00000168874
Phylogenetic Trees/Animal Genes : TreeFamATOH8
HOVERGENQ96SQ7
HOGENOMQ96SQ7
Homologs : HomoloGeneATOH8
Homology/Alignments : Family Browser (UCSC)ATOH8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATOH8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATOH8
dbVarATOH8
ClinVarATOH8
1000_GenomesATOH8 
Exome Variant ServerATOH8
ExAC (Exome Aggregation Consortium)ATOH8 (select the gene name)
Genetic variants : HAPMAP84913
Genomic Variants (DGV)ATOH8 [DGVbeta]
DECIPHERATOH8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATOH8 
Mutations
ICGC Data PortalATOH8 
TCGA Data PortalATOH8 
Broad Tumor PortalATOH8
OASIS PortalATOH8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATOH8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATOH8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATOH8
DgiDB (Drug Gene Interaction Database)ATOH8
DoCM (Curated mutations)ATOH8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATOH8 (select a term)
intoGenATOH8
Cancer3DATOH8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenATOH8
Genetic Testing Registry ATOH8
NextProtQ96SQ7 [Medical]
TSGene84913
GENETestsATOH8
Target ValidationATOH8
Huge Navigator ATOH8 [HugePedia]
snp3D : Map Gene to Disease84913
BioCentury BCIQATOH8
ClinGenATOH8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84913
Chemical/Pharm GKB GenePA134904746
Clinical trialATOH8
Miscellaneous
canSAR (ICR)ATOH8 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATOH8
EVEXATOH8
GoPubMedATOH8
iHOPATOH8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:55:39 CEST 2017

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