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ATOX1 (antioxidant 1 copper chaperone)

Identity

Alias_namesATX1 (antioxidant protein 1, yeast) homolog 1
ATX1 antioxidant protein 1 homolog (yeast)
Alias_symbol (synonym)HAH1
Other aliasATX1
HGNC (Hugo) ATOX1
LocusID (NCBI) 475
Atlas_Id 720
Location 5q33.1  [Link to chromosome band 5q33]
Location_base_pair Starts at 151122383 and ends at 151138210 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATOX1 (5q33.1) / MAP7D3 (Xq26.3)DBNL (7p13) / ATOX1 (5q33.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATOX1   798
Cards
Entrez_Gene (NCBI)ATOX1  475  antioxidant 1 copper chaperone
AliasesATX1; HAH1
GeneCards (Weizmann)ATOX1
Ensembl hg19 (Hinxton)ENSG00000177556 [Gene_View]  chr5:151122383-151138210 [Contig_View]  ATOX1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000177556 [Gene_View]  chr5:151122383-151138210 [Contig_View]  ATOX1 [Vega]
ICGC DataPortalENSG00000177556
TCGA cBioPortalATOX1
AceView (NCBI)ATOX1
Genatlas (Paris)ATOX1
WikiGenes475
SOURCE (Princeton)ATOX1
Genetics Home Reference (NIH)ATOX1
Genomic and cartography
GoldenPath hg19 (UCSC)ATOX1  -     chr5:151122383-151138210 -  5q33.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ATOX1  -     5q33.1   [Description]    (hg38-Dec_2013)
EnsemblATOX1 - 5q33.1 [CytoView hg19]  ATOX1 - 5q33.1 [CytoView hg38]
Mapping of homologs : NCBIATOX1 [Mapview hg19]  ATOX1 [Mapview hg38]
OMIM602270   
Gene and transcription
Genbank (Entrez)AK091843 AK128210 AK293063 BC112248 BC112250
RefSeq transcript (Entrez)NM_004045
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_029289 NW_004929324
Consensus coding sequences : CCDS (NCBI)ATOX1
Cluster EST : UnigeneHs.125213 [ NCBI ]
CGAP (NCI)Hs.125213
Alternative Splicing GalleryENSG00000177556
Gene ExpressionATOX1 [ NCBI-GEO ]   ATOX1 [ EBI - ARRAY_EXPRESS ]   ATOX1 [ SEEK ]   ATOX1 [ MEM ]
Gene Expression Viewer (FireBrowse)ATOX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)475
GTEX Portal (Tissue expression)ATOX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00244   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00244  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00244
Splice isoforms : SwissVarO00244
PhosPhoSitePlusO00244
Domaine pattern : Prosite (Expaxy)HMA_1 (PS01047)    HMA_2 (PS50846)   
Domains : Interpro (EBI)Heavy-metal-associated_CS    HMA_dom   
Domain families : Pfam (Sanger)HMA (PF00403)   
Domain families : Pfam (NCBI)pfam00403   
Conserved Domain (NCBI)ATOX1
DMDM Disease mutations475
Blocks (Seattle)ATOX1
PDB (SRS)1FE0    1FE4    1FEE    1TL4    1TL5    2K1R    2LQ9    3CJK    3IWL    3IWX    4QOT    4YDX    4YEA   
PDB (PDBSum)1FE0    1FE4    1FEE    1TL4    1TL5    2K1R    2LQ9    3CJK    3IWL    3IWX    4QOT    4YDX    4YEA   
PDB (IMB)1FE0    1FE4    1FEE    1TL4    1TL5    2K1R    2LQ9    3CJK    3IWL    3IWX    4QOT    4YDX    4YEA   
PDB (RSDB)1FE0    1FE4    1FEE    1TL4    1TL5    2K1R    2LQ9    3CJK    3IWL    3IWX    4QOT    4YDX    4YEA   
Structural Biology KnowledgeBase1FE0    1FE4    1FEE    1TL4    1TL5    2K1R    2LQ9    3CJK    3IWL    3IWX    4QOT    4YDX    4YEA   
SCOP (Structural Classification of Proteins)1FE0    1FE4    1FEE    1TL4    1TL5    2K1R    2LQ9    3CJK    3IWL    3IWX    4QOT    4YDX    4YEA   
CATH (Classification of proteins structures)1FE0    1FE4    1FEE    1TL4    1TL5    2K1R    2LQ9    3CJK    3IWL    3IWX    4QOT    4YDX    4YEA   
SuperfamilyO00244
Human Protein AtlasENSG00000177556
Peptide AtlasO00244
HPRD03779
IPIIPI00010863   IPI00982850   IPI00981694   
Protein Interaction databases
DIP (DOE-UCLA)O00244
IntAct (EBI)O00244
FunCoupENSG00000177556
BioGRIDATOX1
STRING (EMBL)ATOX1
ZODIACATOX1
Ontologies - Pathways
QuickGOO00244
Ontology : AmiGOcopper ion transmembrane transporter activity  copper ion binding  protein binding  cytosol  copper ion transport  cellular copper ion homeostasis  response to oxidative stress  intracellular copper ion transport  metallochaperone activity  copper chaperone activity  copper-dependent protein binding  copper ion transmembrane transport  
Ontology : EGO-EBIcopper ion transmembrane transporter activity  copper ion binding  protein binding  cytosol  copper ion transport  cellular copper ion homeostasis  response to oxidative stress  intracellular copper ion transport  metallochaperone activity  copper chaperone activity  copper-dependent protein binding  copper ion transmembrane transport  
Pathways : KEGGMineral absorption   
NDEx NetworkATOX1
Atlas of Cancer Signalling NetworkATOX1
Wikipedia pathwaysATOX1
Orthology - Evolution
OrthoDB475
GeneTree (enSembl)ENSG00000177556
Phylogenetic Trees/Animal Genes : TreeFamATOX1
HOVERGENO00244
HOGENOMO00244
Homologs : HomoloGeneATOX1
Homology/Alignments : Family Browser (UCSC)ATOX1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATOX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATOX1
dbVarATOX1
ClinVarATOX1
1000_GenomesATOX1 
Exome Variant ServerATOX1
ExAC (Exome Aggregation Consortium)ATOX1 (select the gene name)
Genetic variants : HAPMAP475
Genomic Variants (DGV)ATOX1 [DGVbeta]
DECIPHER (Syndromes)5:151122383-151138210  ENSG00000177556
CONAN: Copy Number AnalysisATOX1 
Mutations
ICGC Data PortalATOX1 
TCGA Data PortalATOX1 
Broad Tumor PortalATOX1
OASIS PortalATOX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATOX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATOX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATOX1
DgiDB (Drug Gene Interaction Database)ATOX1
DoCM (Curated mutations)ATOX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATOX1 (select a term)
intoGenATOX1
Cancer3DATOX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602270   
Orphanet
MedgenATOX1
Genetic Testing Registry ATOX1
NextProtO00244 [Medical]
TSGene475
GENETestsATOX1
Huge Navigator ATOX1 [HugePedia]
snp3D : Map Gene to Disease475
BioCentury BCIQATOX1
ClinGenATOX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD475
Chemical/Pharm GKB GenePA25096
Clinical trialATOX1
Miscellaneous
canSAR (ICR)ATOX1 (select the gene name)
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATOX1
EVEXATOX1
GoPubMedATOX1
iHOPATOX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 30 14:53:21 CEST 2017

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