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ATP10B (ATPase phospholipid transporting 10B (putative))

Identity

Alias_namesATPase
Alias_symbol (synonym)ATPVB
KIAA0715
FLJ21477
Other alias
HGNC (Hugo) ATP10B
LocusID (NCBI) 23120
Atlas_Id 52459
Location 5q34  [Link to chromosome band 5q34]
Location_base_pair Starts at 160563120 and ends at 160852212 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATP10B (5q34) / ATP6AP1 (Xq28)NPIPB7 (16q23.1) / ATP10B (5q34)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;5)(q23;q34) ATP10B/COMMD10


External links

Nomenclature
HGNC (Hugo)ATP10B   13543
Cards
Entrez_Gene (NCBI)ATP10B  23120  ATPase phospholipid transporting 10B (putative)
AliasesATPVB
GeneCards (Weizmann)ATP10B
Ensembl hg19 (Hinxton)ENSG00000118322 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118322 [Gene_View]  ENSG00000118322 [Sequence]  chr5:160563120-160852212 [Contig_View]  ATP10B [Vega]
ICGC DataPortalENSG00000118322
TCGA cBioPortalATP10B
AceView (NCBI)ATP10B
Genatlas (Paris)ATP10B
WikiGenes23120
SOURCE (Princeton)ATP10B
Genetics Home Reference (NIH)ATP10B
Genomic and cartography
GoldenPath hg38 (UCSC)ATP10B  -     chr5:160563120-160852212 -  5q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATP10B  -     5q34   [Description]    (hg19-Feb_2009)
EnsemblATP10B - 5q34 [CytoView hg19]  ATP10B - 5q34 [CytoView hg38]
Mapping of homologs : NCBIATP10B [Mapview hg19]  ATP10B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB018258 AK024894 AK025130 AK025290 AK025294
RefSeq transcript (Entrez)NM_025153
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATP10B
Cluster EST : UnigeneHs.109358 [ NCBI ]
CGAP (NCI)Hs.109358
Alternative Splicing GalleryENSG00000118322
Gene ExpressionATP10B [ NCBI-GEO ]   ATP10B [ EBI - ARRAY_EXPRESS ]   ATP10B [ SEEK ]   ATP10B [ MEM ]
Gene Expression Viewer (FireBrowse)ATP10B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23120
GTEX Portal (Tissue expression)ATP10B
Human Protein AtlasENSG00000118322-ATP10B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94823   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94823  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94823
Splice isoforms : SwissVarO94823
Catalytic activity : Enzyme3.6.3.1 [ Enzyme-Expasy ]   3.6.3.13.6.3.1 [ IntEnz-EBI ]   3.6.3.1 [ BRENDA ]   3.6.3.1 [ KEGG ]   
PhosPhoSitePlusO94823
Domaine pattern : Prosite (Expaxy)ATPASE_E1_E2 (PS00154)   
Domains : Interpro (EBI)ATP10B    ATPase_P-typ_cyto_domN    ATPase_P-typ_P_site    ATPase_P-typ_transduc_dom_A    HAD-like_dom    P-type_ATPase_IV    P-type_ATPase_N    P_typ_ATPase    P_typ_ATPase_c   
Domain families : Pfam (Sanger)E1-E2_ATPase (PF00122)    PhoLip_ATPase_C (PF16212)    PhoLip_ATPase_N (PF16209)   
Domain families : Pfam (NCBI)pfam00122    pfam16212    pfam16209   
Conserved Domain (NCBI)ATP10B
DMDM Disease mutations23120
Blocks (Seattle)ATP10B
SuperfamilyO94823
Human Protein Atlas [tissue]ENSG00000118322-ATP10B [tissue]
Peptide AtlasO94823
HPRD08637
IPIIPI00852619   IPI00293928   IPI00186385   IPI00982021   
Protein Interaction databases
DIP (DOE-UCLA)O94823
IntAct (EBI)O94823
FunCoupENSG00000118322
BioGRIDATP10B
STRING (EMBL)ATP10B
ZODIACATP10B
Ontologies - Pathways
QuickGOO94823
Ontology : AmiGOmagnesium ion binding  phospholipid-translocating ATPase activity  protein binding  ATP binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  integral component of membrane  cytoplasmic vesicle membrane  phospholipid translocation  
Ontology : EGO-EBImagnesium ion binding  phospholipid-translocating ATPase activity  protein binding  ATP binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  integral component of membrane  cytoplasmic vesicle membrane  phospholipid translocation  
NDEx NetworkATP10B
Atlas of Cancer Signalling NetworkATP10B
Wikipedia pathwaysATP10B
Orthology - Evolution
OrthoDB23120
GeneTree (enSembl)ENSG00000118322
Phylogenetic Trees/Animal Genes : TreeFamATP10B
HOVERGENO94823
HOGENOMO94823
Homologs : HomoloGeneATP10B
Homology/Alignments : Family Browser (UCSC)ATP10B
Gene fusions - Rearrangements
Fusion : QuiverATP10B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATP10B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATP10B
dbVarATP10B
ClinVarATP10B
1000_GenomesATP10B 
Exome Variant ServerATP10B
ExAC (Exome Aggregation Consortium)ENSG00000118322
GNOMAD BrowserENSG00000118322
Genetic variants : HAPMAP23120
Genomic Variants (DGV)ATP10B [DGVbeta]
DECIPHERATP10B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATP10B 
Mutations
ICGC Data PortalATP10B 
TCGA Data PortalATP10B 
Broad Tumor PortalATP10B
OASIS PortalATP10B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATP10B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATP10B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATP10B
DgiDB (Drug Gene Interaction Database)ATP10B
DoCM (Curated mutations)ATP10B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATP10B (select a term)
intoGenATP10B
Cancer3DATP10B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETATP10B
MedgenATP10B
Genetic Testing Registry ATP10B
NextProtO94823 [Medical]
TSGene23120
GENETestsATP10B
Target ValidationATP10B
Huge Navigator ATP10B [HugePedia]
snp3D : Map Gene to Disease23120
BioCentury BCIQATP10B
ClinGenATP10B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23120
Chemical/Pharm GKB GenePA25098
Clinical trialATP10B
Miscellaneous
canSAR (ICR)ATP10B (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATP10B
EVEXATP10B
GoPubMedATP10B
iHOPATP10B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:15:23 CEST 2018

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