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ATP11B (ATPase phospholipid transporting 11B (putative))

Identity

Alias_namesATPase
Alias_symbol (synonym)ATPIF
ATPIR
KIAA0956
Other alias
HGNC (Hugo) ATP11B
LocusID (NCBI) 23200
Atlas_Id 52406
Location 3q26.33  [Link to chromosome band 3q26]
Location_base_pair Starts at 182793503 and ends at 182921633 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP11B (3q26.33) / GCLC (6p12.1)ATP11B (3q26.33) / MED10 (5p15.31)ATP11B (3q26.33) / POU3F1 (1p34.3)
ATP11B (3q26.33) / SI (3q26.1)ATP11B (3q26.33) / SOX2-OT (3q26.33)ATP11B (3q26.33) / TFRC (3q29)
ATP11B (3q26.33) / TPTEP1 (22q11.1)ATP11B (3q26.33) / ZNF595 (4p16.3)BCAM (19q13.32) / ATP11B (3q26.33)
DCUN1D1 (3q26.33) / ATP11B (3q26.33)DFFA (1p36.22) / ATP11B (3q26.33)PDE3B (11p15.2) / ATP11B (3q26.33)
TPTEP1 (22q11.1) / ATP11B (3q26.33)ZNF595 (4p16.3) / ATP11B (3q26.33)ATP11B 3q26.33 / MED10 5p15.31
ATP11B 3q26.33 / TFRC 3q29

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Lung: Translocations in Small Cell Carcinoma
Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ATP11B   13553
Cards
Entrez_Gene (NCBI)ATP11B  23200  ATPase phospholipid transporting 11B (putative)
AliasesATPIF; ATPIR
GeneCards (Weizmann)ATP11B
Ensembl hg19 (Hinxton)ENSG00000058063 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000058063 [Gene_View]  chr3:182793503-182921633 [Contig_View]  ATP11B [Vega]
ICGC DataPortalENSG00000058063
TCGA cBioPortalATP11B
AceView (NCBI)ATP11B
Genatlas (Paris)ATP11B
WikiGenes23200
SOURCE (Princeton)ATP11B
Genetics Home Reference (NIH)ATP11B
Genomic and cartography
GoldenPath hg38 (UCSC)ATP11B  -     chr3:182793503-182921633 +  3q26.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATP11B  -     3q26.33   [Description]    (hg19-Feb_2009)
EnsemblATP11B - 3q26.33 [CytoView hg19]  ATP11B - 3q26.33 [CytoView hg38]
Mapping of homologs : NCBIATP11B [Mapview hg19]  ATP11B [Mapview hg38]
OMIM605869   
Gene and transcription
Genbank (Entrez)AB023173 AF156548 AK093727 AK296750 AK304855
RefSeq transcript (Entrez)NM_014616
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATP11B
Cluster EST : UnigeneHs.478429 [ NCBI ]
CGAP (NCI)Hs.478429
Alternative Splicing GalleryENSG00000058063
Gene ExpressionATP11B [ NCBI-GEO ]   ATP11B [ EBI - ARRAY_EXPRESS ]   ATP11B [ SEEK ]   ATP11B [ MEM ]
Gene Expression Viewer (FireBrowse)ATP11B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23200
GTEX Portal (Tissue expression)ATP11B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2G3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2G3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2G3
Splice isoforms : SwissVarQ9Y2G3
Catalytic activity : Enzyme3.6.3.1 [ Enzyme-Expasy ]   3.6.3.13.6.3.1 [ IntEnz-EBI ]   3.6.3.1 [ BRENDA ]   3.6.3.1 [ KEGG ]   
PhosPhoSitePlusQ9Y2G3
Domaine pattern : Prosite (Expaxy)ATPASE_E1_E2 (PS00154)   
Domains : Interpro (EBI)ATP11B    ATPase_P-typ_cyto_domN    ATPase_P-typ_P_site    ATPase_P-typ_transduc_dom_A    HAD-like_dom    P-type_ATPase_IV    P-type_ATPase_N    P_typ_ATPase    P_typ_ATPase_c   
Domain families : Pfam (Sanger)E1-E2_ATPase (PF00122)    PhoLip_ATPase_C (PF16212)    PhoLip_ATPase_N (PF16209)   
Domain families : Pfam (NCBI)pfam00122    pfam16212    pfam16209   
Conserved Domain (NCBI)ATP11B
DMDM Disease mutations23200
Blocks (Seattle)ATP11B
SuperfamilyQ9Y2G3
Human Protein AtlasENSG00000058063
Peptide AtlasQ9Y2G3
HPRD10432
IPIIPI00240793   IPI00908989   IPI00945653   IPI00947360   IPI00789084   IPI00796034   IPI00385343   IPI00945453   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2G3
IntAct (EBI)Q9Y2G3
FunCoupENSG00000058063
BioGRIDATP11B
STRING (EMBL)ATP11B
ZODIACATP11B
Ontologies - Pathways
QuickGOQ9Y2G3
Ontology : AmiGOmagnesium ion binding  phospholipid-translocating ATPase activity  protein binding  ATP binding  nuclear inner membrane  early endosome  endoplasmic reticulum  Golgi apparatus  plasma membrane  plasma membrane  ion transport  ion transmembrane transporter activity  aminophospholipid transport  membrane  integral component of membrane  ion transmembrane transport  azurophil granule membrane  neutrophil degranulation  phospholipid translocation  recycling endosome  recycling endosome membrane  
Ontology : EGO-EBImagnesium ion binding  phospholipid-translocating ATPase activity  protein binding  ATP binding  nuclear inner membrane  early endosome  endoplasmic reticulum  Golgi apparatus  plasma membrane  plasma membrane  ion transport  ion transmembrane transporter activity  aminophospholipid transport  membrane  integral component of membrane  ion transmembrane transport  azurophil granule membrane  neutrophil degranulation  phospholipid translocation  recycling endosome  recycling endosome membrane  
NDEx NetworkATP11B
Atlas of Cancer Signalling NetworkATP11B
Wikipedia pathwaysATP11B
Orthology - Evolution
OrthoDB23200
GeneTree (enSembl)ENSG00000058063
Phylogenetic Trees/Animal Genes : TreeFamATP11B
HOVERGENQ9Y2G3
HOGENOMQ9Y2G3
Homologs : HomoloGeneATP11B
Homology/Alignments : Family Browser (UCSC)ATP11B
Gene fusions - Rearrangements
Fusion : MitelmanATP11B/MED10 [3q26.33/5p15.31]  
Fusion : MitelmanATP11B/POU3F1 [3q26.33/1p34.3]  [t(1;3)(p34;q26)]  
Fusion : MitelmanATP11B/SI [3q26.33/3q26.1]  [t(3;3)(q26;q26)]  
Fusion : MitelmanATP11B/SOX2-OT [3q26.33/3q26.33]  [t(3;3)(q26;q26)]  
Fusion : MitelmanATP11B/TFRC [3q26.33/3q29]  [t(3;3)(q26;q29)]  
Fusion : MitelmanATP11B/TPTEP1 [3q26.33/22q11.1]  [t(3;22)(q26;q11)]  
Fusion : MitelmanATP11B/ZNF595 [3q26.33/4p16.3]  [t(3;4)(q26;p16)]  
Fusion : MitelmanDCUN1D1/ATP11B [3q26.33/3q26.33]  [inv(3)(q26q27)]  
Fusion : MitelmanPDE3B/ATP11B [11p15.2/3q26.33]  [t(3;11)(q26;p15)]  
Fusion : MitelmanTPTEP1/ATP11B [22q11.1/3q26.33]  [t(3;22)(q26;q11)]  
Fusion : MitelmanZNF595/ATP11B [4p16.3/3q26.33]  [t(3;4)(q26;p16)]  
Fusion: TCGAATP11B 3q26.33 MED10 5p15.31 BRCA
Fusion: TCGAATP11B 3q26.33 TFRC 3q29 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATP11B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATP11B
dbVarATP11B
ClinVarATP11B
1000_GenomesATP11B 
Exome Variant ServerATP11B
ExAC (Exome Aggregation Consortium)ATP11B (select the gene name)
Genetic variants : HAPMAP23200
Genomic Variants (DGV)ATP11B [DGVbeta]
DECIPHERATP11B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATP11B 
Mutations
ICGC Data PortalATP11B 
TCGA Data PortalATP11B 
Broad Tumor PortalATP11B
OASIS PortalATP11B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATP11B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATP11B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATP11B
DgiDB (Drug Gene Interaction Database)ATP11B
DoCM (Curated mutations)ATP11B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATP11B (select a term)
intoGenATP11B
Cancer3DATP11B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605869   
Orphanet
MedgenATP11B
Genetic Testing Registry ATP11B
NextProtQ9Y2G3 [Medical]
TSGene23200
GENETestsATP11B
Target ValidationATP11B
Huge Navigator ATP11B [HugePedia]
snp3D : Map Gene to Disease23200
BioCentury BCIQATP11B
ClinGenATP11B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23200
Chemical/Pharm GKB GenePA25102
Clinical trialATP11B
Miscellaneous
canSAR (ICR)ATP11B (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATP11B
EVEXATP11B
GoPubMedATP11B
iHOPATP11B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:24:49 CEST 2017

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