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ATP1B2 (ATPase Na+/K+ transporting subunit beta 2)

Identity

Alias_namesATPase
Alias_symbol (synonym)AMOG
Other alias
HGNC (Hugo) ATP1B2
LocusID (NCBI) 482
Atlas_Id 721
Location 17p13.1  [Link to chromosome band 17p13]
Location_base_pair Starts at 7646627 and ends at 7657771 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP1B2 (17p13.1) / ALDH3A2 (17p11.2)ATP1B2 (17p13.1) / SNCB (5q35.2)B3GAT3 (11q12.3) / ATP1B2 (17p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATP1B2   805
Cards
Entrez_Gene (NCBI)ATP1B2  482  ATPase Na+/K+ transporting subunit beta 2
AliasesAMOG
GeneCards (Weizmann)ATP1B2
Ensembl hg19 (Hinxton)ENSG00000129244 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129244 [Gene_View]  chr17:7646627-7657771 [Contig_View]  ATP1B2 [Vega]
ICGC DataPortalENSG00000129244
TCGA cBioPortalATP1B2
AceView (NCBI)ATP1B2
Genatlas (Paris)ATP1B2
WikiGenes482
SOURCE (Princeton)ATP1B2
Genetics Home Reference (NIH)ATP1B2
Genomic and cartography
GoldenPath hg38 (UCSC)ATP1B2  -     chr17:7646627-7657771 +  17p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATP1B2  -     17p13.1   [Description]    (hg19-Feb_2009)
EnsemblATP1B2 - 17p13.1 [CytoView hg19]  ATP1B2 - 17p13.1 [CytoView hg38]
Mapping of homologs : NCBIATP1B2 [Mapview hg19]  ATP1B2 [Mapview hg38]
OMIM182331   
Gene and transcription
Genbank (Entrez)AK290143 AL120033 AL532023 AY946017 BC035801
RefSeq transcript (Entrez)NM_001303263 NM_001678
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATP1B2
Cluster EST : UnigeneHs.643540 [ NCBI ]
CGAP (NCI)Hs.643540
Alternative Splicing GalleryENSG00000129244
Gene ExpressionATP1B2 [ NCBI-GEO ]   ATP1B2 [ EBI - ARRAY_EXPRESS ]   ATP1B2 [ SEEK ]   ATP1B2 [ MEM ]
Gene Expression Viewer (FireBrowse)ATP1B2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)482
GTEX Portal (Tissue expression)ATP1B2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP14415   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP14415  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP14415
Splice isoforms : SwissVarP14415
PhosPhoSitePlusP14415
Domaine pattern : Prosite (Expaxy)ATPASE_NA_K_BETA_1 (PS00390)    ATPASE_NA_K_BETA_2 (PS00391)   
Domains : Interpro (EBI)Na/K_ATPase_sub_beta   
Domain families : Pfam (Sanger)Na_K-ATPase (PF00287)   
Domain families : Pfam (NCBI)pfam00287   
Conserved Domain (NCBI)ATP1B2
DMDM Disease mutations482
Blocks (Seattle)ATP1B2
SuperfamilyP14415
Human Protein AtlasENSG00000129244
Peptide AtlasP14415
HPRD01664
IPIIPI00293971   
Protein Interaction databases
DIP (DOE-UCLA)P14415
IntAct (EBI)P14415
FunCoupENSG00000129244
BioGRIDATP1B2
STRING (EMBL)ATP1B2
ZODIACATP1B2
Ontologies - Pathways
QuickGOP14415
Ontology : AmiGOATPase activator activity  sodium:potassium-exchanging ATPase activity  sodium:potassium-exchanging ATPase activity  protein binding  cytoplasm  plasma membrane  sodium:potassium-exchanging ATPase complex  transport  cellular sodium ion homeostasis  cell adhesion  potassium ion import  establishment or maintenance of transmembrane electrochemical gradient  apical plasma membrane  cellular potassium ion homeostasis  positive regulation of ATPase activity  ion transmembrane transport  sodium ion export from cell  protein stabilization  leukocyte migration  ATPase binding  membrane repolarization  cell communication by electrical coupling involved in cardiac conduction  ATP hydrolysis coupled transmembrane transport  positive regulation of potassium ion transmembrane transporter activity  positive regulation of sodium ion export from cell  positive regulation of potassium ion import  regulation of cardiac conduction  
Ontology : EGO-EBIATPase activator activity  sodium:potassium-exchanging ATPase activity  sodium:potassium-exchanging ATPase activity  protein binding  cytoplasm  plasma membrane  sodium:potassium-exchanging ATPase complex  transport  cellular sodium ion homeostasis  cell adhesion  potassium ion import  establishment or maintenance of transmembrane electrochemical gradient  apical plasma membrane  cellular potassium ion homeostasis  positive regulation of ATPase activity  ion transmembrane transport  sodium ion export from cell  protein stabilization  leukocyte migration  ATPase binding  membrane repolarization  cell communication by electrical coupling involved in cardiac conduction  ATP hydrolysis coupled transmembrane transport  positive regulation of potassium ion transmembrane transporter activity  positive regulation of sodium ion export from cell  positive regulation of potassium ion import  regulation of cardiac conduction  
Pathways : KEGG   
NDEx NetworkATP1B2
Atlas of Cancer Signalling NetworkATP1B2
Wikipedia pathwaysATP1B2
Orthology - Evolution
OrthoDB482
GeneTree (enSembl)ENSG00000129244
Phylogenetic Trees/Animal Genes : TreeFamATP1B2
HOVERGENP14415
HOGENOMP14415
Homologs : HomoloGeneATP1B2
Homology/Alignments : Family Browser (UCSC)ATP1B2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATP1B2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATP1B2
dbVarATP1B2
ClinVarATP1B2
1000_GenomesATP1B2 
Exome Variant ServerATP1B2
ExAC (Exome Aggregation Consortium)ATP1B2 (select the gene name)
Genetic variants : HAPMAP482
Genomic Variants (DGV)ATP1B2 [DGVbeta]
DECIPHERATP1B2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATP1B2 
Mutations
ICGC Data PortalATP1B2 
TCGA Data PortalATP1B2 
Broad Tumor PortalATP1B2
OASIS PortalATP1B2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATP1B2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATP1B2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATP1B2
DgiDB (Drug Gene Interaction Database)ATP1B2
DoCM (Curated mutations)ATP1B2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATP1B2 (select a term)
intoGenATP1B2
Cancer3DATP1B2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182331   
Orphanet
MedgenATP1B2
Genetic Testing Registry ATP1B2
NextProtP14415 [Medical]
TSGene482
GENETestsATP1B2
Huge Navigator ATP1B2 [HugePedia]
snp3D : Map Gene to Disease482
BioCentury BCIQATP1B2
ClinGenATP1B2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD482
Chemical/Pharm GKB GenePA67
Clinical trialATP1B2
Miscellaneous
canSAR (ICR)ATP1B2 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATP1B2
EVEXATP1B2
GoPubMedATP1B2
iHOPATP1B2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:07:07 CEST 2017

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