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ATP1B3 (ATPase Na+/K+ transporting subunit beta 3)

Identity

Alias_namesATPase
Alias_symbol (synonym)FLJ29027
CD298
Other aliasATPB-3
HGNC (Hugo) ATP1B3
LocusID (NCBI) 483
Atlas_Id 54860
Location 3q23  [Link to chromosome band 3q23]
Location_base_pair Starts at 141876592 and ends at 141926548 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP1B3 (3q23) / RNF7 (3q23)ATP1B3 3q23 / RNF7 3q23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATP1B3   806
Cards
Entrez_Gene (NCBI)ATP1B3  483  ATPase Na+/K+ transporting subunit beta 3
AliasesATPB-3; CD298
GeneCards (Weizmann)ATP1B3
Ensembl hg19 (Hinxton)ENSG00000069849 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000069849 [Gene_View]  chr3:141876592-141926548 [Contig_View]  ATP1B3 [Vega]
ICGC DataPortalENSG00000069849
TCGA cBioPortalATP1B3
AceView (NCBI)ATP1B3
Genatlas (Paris)ATP1B3
WikiGenes483
SOURCE (Princeton)ATP1B3
Genetics Home Reference (NIH)ATP1B3
Genomic and cartography
GoldenPath hg38 (UCSC)ATP1B3  -     chr3:141876592-141926548 +  3q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATP1B3  -     3q23   [Description]    (hg19-Feb_2009)
EnsemblATP1B3 - 3q23 [CytoView hg19]  ATP1B3 - 3q23 [CytoView hg38]
Mapping of homologs : NCBIATP1B3 [Mapview hg19]  ATP1B3 [Mapview hg38]
OMIM601867   
Gene and transcription
Genbank (Entrez)AK094673 AK131061 AK293697 AY946018 BC001469
RefSeq transcript (Entrez)NM_001679
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATP1B3
Cluster EST : UnigeneHs.477789 [ NCBI ]
CGAP (NCI)Hs.477789
Alternative Splicing GalleryENSG00000069849
Gene ExpressionATP1B3 [ NCBI-GEO ]   ATP1B3 [ EBI - ARRAY_EXPRESS ]   ATP1B3 [ SEEK ]   ATP1B3 [ MEM ]
Gene Expression Viewer (FireBrowse)ATP1B3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)483
GTEX Portal (Tissue expression)ATP1B3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54709   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP54709  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP54709
Splice isoforms : SwissVarP54709
PhosPhoSitePlusP54709
Domaine pattern : Prosite (Expaxy)ATPASE_NA_K_BETA_1 (PS00390)   
Domains : Interpro (EBI)Na/K_ATPase_sub_beta   
Domain families : Pfam (Sanger)Na_K-ATPase (PF00287)   
Domain families : Pfam (NCBI)pfam00287   
Conserved Domain (NCBI)ATP1B3
DMDM Disease mutations483
Blocks (Seattle)ATP1B3
SuperfamilyP54709
Human Protein AtlasENSG00000069849
Peptide AtlasP54709
HPRD03521
IPIIPI00008167   IPI00787965   IPI00945216   IPI00945384   IPI00944896   IPI00793333   IPI00946024   
Protein Interaction databases
DIP (DOE-UCLA)P54709
IntAct (EBI)P54709
FunCoupENSG00000069849
BioGRIDATP1B3
STRING (EMBL)ATP1B3
ZODIACATP1B3
Ontologies - Pathways
QuickGOP54709
Ontology : AmiGOATPase activator activity  sodium:potassium-exchanging ATPase activity  sodium:potassium-exchanging ATPase activity  plasma membrane  plasma membrane  sodium:potassium-exchanging ATPase complex  caveola  transport  cellular sodium ion homeostasis  potassium ion import  establishment or maintenance of transmembrane electrochemical gradient  cellular potassium ion homeostasis  positive regulation of ATPase activity  ion transmembrane transport  sodium ion export from cell  melanosome  protein stabilization  leukocyte migration  ATPase binding  extracellular exosome  protein localization to plasma membrane  membrane repolarization  ATP hydrolysis coupled transmembrane transport  positive regulation of potassium ion transmembrane transporter activity  positive regulation of sodium ion export from cell  positive regulation of potassium ion import  regulation of cardiac conduction  
Ontology : EGO-EBIATPase activator activity  sodium:potassium-exchanging ATPase activity  sodium:potassium-exchanging ATPase activity  plasma membrane  plasma membrane  sodium:potassium-exchanging ATPase complex  caveola  transport  cellular sodium ion homeostasis  potassium ion import  establishment or maintenance of transmembrane electrochemical gradient  cellular potassium ion homeostasis  positive regulation of ATPase activity  ion transmembrane transport  sodium ion export from cell  melanosome  protein stabilization  leukocyte migration  ATPase binding  extracellular exosome  protein localization to plasma membrane  membrane repolarization  ATP hydrolysis coupled transmembrane transport  positive regulation of potassium ion transmembrane transporter activity  positive regulation of sodium ion export from cell  positive regulation of potassium ion import  regulation of cardiac conduction  
Pathways : KEGG   
NDEx NetworkATP1B3
Atlas of Cancer Signalling NetworkATP1B3
Wikipedia pathwaysATP1B3
Orthology - Evolution
OrthoDB483
GeneTree (enSembl)ENSG00000069849
Phylogenetic Trees/Animal Genes : TreeFamATP1B3
HOVERGENP54709
HOGENOMP54709
Homologs : HomoloGeneATP1B3
Homology/Alignments : Family Browser (UCSC)ATP1B3
Gene fusions - Rearrangements
Fusion: TCGAATP1B3 3q23 RNF7 3q23 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATP1B3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATP1B3
dbVarATP1B3
ClinVarATP1B3
1000_GenomesATP1B3 
Exome Variant ServerATP1B3
ExAC (Exome Aggregation Consortium)ATP1B3 (select the gene name)
Genetic variants : HAPMAP483
Genomic Variants (DGV)ATP1B3 [DGVbeta]
DECIPHERATP1B3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATP1B3 
Mutations
ICGC Data PortalATP1B3 
TCGA Data PortalATP1B3 
Broad Tumor PortalATP1B3
OASIS PortalATP1B3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATP1B3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATP1B3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATP1B3
DgiDB (Drug Gene Interaction Database)ATP1B3
DoCM (Curated mutations)ATP1B3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATP1B3 (select a term)
intoGenATP1B3
Cancer3DATP1B3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601867   
Orphanet
MedgenATP1B3
Genetic Testing Registry ATP1B3
NextProtP54709 [Medical]
TSGene483
GENETestsATP1B3
Target ValidationATP1B3
Huge Navigator ATP1B3 [HugePedia]
snp3D : Map Gene to Disease483
BioCentury BCIQATP1B3
ClinGenATP1B3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD483
Chemical/Pharm GKB GenePA68
Clinical trialATP1B3
Miscellaneous
canSAR (ICR)ATP1B3 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATP1B3
EVEXATP1B3
GoPubMedATP1B3
iHOPATP1B3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:55:41 CEST 2017

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