Identity
HGNC
LOCATION
12q21.33
LOCUSID
ALIAS
PMCA1,PMCA1kb
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 490
MIM: 108731
HGNC: 814
Ensembl: ENSG00000070961
Variants:
dbSNP: 490
ClinVar: 490
TCGA: ENSG00000070961
COSMIC: ATP2B1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164712445 | Antihypertensives | Chemical | ClinicalAnnotation | associated | PD | 25385345 | |
| PA443796 | Coronary Artery Disease | Disease | ClinicalAnnotation | associated | PD | 25385345 | |
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | 25385345 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37211801 | 2024 | Association between polymorphism and haplotype of ATP2B1 gene and skeletal fluorosis in Han population. | 0 |
| 38430457 | 2024 | ATP2B1 gene polymorphisms associated with resistant hypertension in the Japanese population. | 1 |
| 37211801 | 2024 | Association between polymorphism and haplotype of ATP2B1 gene and skeletal fluorosis in Han population. | 0 |
| 38430457 | 2024 | ATP2B1 gene polymorphisms associated with resistant hypertension in the Japanese population. | 1 |
| 35469971 | 2023 | The Plasma Membrane Ca(2+)-ATPase, a Molecular Target for Tau-induced Cytosolic Calcium Dysregulation. | 1 |
| 36916084 | 2023 | ATP2B1-AS1 exacerbates sepsis-induced cell apoptosis and inflammation by regulating miR-23a-3p/TLR4 axis. | 1 |
| 35469971 | 2023 | The Plasma Membrane Ca(2+)-ATPase, a Molecular Target for Tau-induced Cytosolic Calcium Dysregulation. | 1 |
| 36916084 | 2023 | ATP2B1-AS1 exacerbates sepsis-induced cell apoptosis and inflammation by regulating miR-23a-3p/TLR4 axis. | 1 |
| 35031021 | 2022 | Re-wiring and gene expression changes of AC025034.1 and ATP2B1 play complex roles in early-to-late breast cancer progression. | 6 |
| 35253182 | 2022 | ATP2B1 gene rs71454161, rs73196661 and rs73196675 polymorphisms in eclampsia. | 0 |
| 35358416 | 2022 | De novo variants in ATP2B1 lead to neurodevelopmental delay. | 7 |
| 35031021 | 2022 | Re-wiring and gene expression changes of AC025034.1 and ATP2B1 play complex roles in early-to-late breast cancer progression. | 6 |
| 35253182 | 2022 | ATP2B1 gene rs71454161, rs73196661 and rs73196675 polymorphisms in eclampsia. | 0 |
| 35358416 | 2022 | De novo variants in ATP2B1 lead to neurodevelopmental delay. | 7 |
| 33760199 | 2021 | Serum from patients with hypertension promotes endothelial dysfunction to induce trophoblast invasion through the miR‑27b‑3p/ATPase plasma membrane Ca(2+) transporting 1 axis. | 4 |
Citation
Dessen P
ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43761/atp2b1
