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ATP2B2 (ATPase, Ca++ transporting, plasma membrane 2)

Identity

Other namesPMCA2
PMCA2a
PMCA2i
HGNC (Hugo) ATP2B2
LocusID (NCBI) 491
Location 3p25.3
Location_base_pair Starts at 10365707 and ends at 10547268 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ATP2B2   815
Cards
Entrez_Gene (NCBI)ATP2B2  491  ATPase, Ca++ transporting, plasma membrane 2
GeneCards (Weizmann)ATP2B2
Ensembl (Hinxton)ENSG00000157087 [Gene_View]  chr3:10365707-10547268 [Contig_View]  ATP2B2 [Vega]
AceView (NCBI)ATP2B2
Genatlas (Paris)ATP2B2
WikiGenes491
SOURCE (Princeton)NM_001001331 NM_001683
Genomic and cartography
GoldenPath (UCSC)ATP2B2  -  3p25.3   chr3:10365707-10547268 -  3p25.3   [Description]    (hg19-Feb_2009)
EnsemblATP2B2 - 3p25.3 [CytoView]
Mapping of homologs : NCBIATP2B2 [Mapview]
OMIM108733   601386   
Gene and transcription
Genbank (Entrez)AA197323 AB210008 AK308898 AL134596 BC019853
RefSeq transcript (Entrez)NM_001001331 NM_001683
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_012046 NT_022517 NW_001838876 NW_001838877 NW_004929309
Consensus coding sequences : CCDS (NCBI)ATP2B2
Cluster EST : UnigeneHs.268942 [ NCBI ]
CGAP (NCI)Hs.268942
Alternative Splicing : Fast-db (Paris)GSHG0021516
Alternative Splicing GalleryENSG00000157087
Gene ExpressionATP2B2 [ NCBI-GEO ]     ATP2B2 [ SEEK ]   ATP2B2 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01814 (Uniprot)
NextProtQ01814  [Medical]
With graphics : InterProQ01814
Splice isoforms : SwissVarQ01814 (Swissvar)
Catalytic activity : Enzyme3.6.3.8 [ Enzyme-Expasy ]   3.6.3.83.6.3.8 [ IntEnz-EBI ]   3.6.3.8 [ BRENDA ]   3.6.3.8 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ATPASE_E1_E2 (PS00154)   
Domains : Interpro (EBI)ATP_Ca_trans_C    ATPase_P-typ_Ca-transp_plasma    ATPase_P-typ_cation-transptr_C    ATPase_P-typ_cation-transptr_N    ATPase_P-typ_cyto_domN    ATPase_P-typ_P_site    ATPase_P-typ_TM_dom    ATPase_P-typ_transduc_dom_A    Cation_transp_P_typ_ATPase    HAD-like_dom   
Related proteins : CluSTrQ01814
Domain families : Pfam (Sanger)ATP_Ca_trans_C (PF12424)    Cation_ATPase_C (PF00689)    Cation_ATPase_N (PF00690)    E1-E2_ATPase (PF00122)    Hydrolase (PF00702)   
Domain families : Pfam (NCBI)pfam12424    pfam00689    pfam00690    pfam00122    pfam00702   
Domain families : Smart (EMBL)Cation_ATPase_N (SM00831)  
DMDM Disease mutations491
Blocks (Seattle)Q01814
Human Protein AtlasENSG00000157087
Peptide AtlasQ01814
HPRD00160
IPIIPI00009791   IPI00219293   IPI00219295   IPI00219296   IPI00219297   IPI01008870   IPI01008982   IPI00219294   IPI00827630   IPI01018624   
Protein Interaction databases
DIP (DOE-UCLA)Q01814
IntAct (EBI)Q01814
FunCoupENSG00000157087
BioGRIDATP2B2
InParanoidQ01814
Interologous Interaction database Q01814
IntegromeDBATP2B2
STRING (EMBL)ATP2B2
Ontologies - Pathways
Ontology : AmiGOcalcium-transporting ATPase activity  calcium-transporting ATPase activity  calcium ion binding  protein binding  calmodulin binding  calmodulin binding  ATP binding  ATP binding  cytoplasm  endoplasmic reticulum  plasma membrane  plasma membrane  plasma membrane  cilium  transport  calcium ion transport  organelle organization  lactation  blood coagulation  sensory perception of sound  locomotory behavior  protein C-terminus binding  regulation of cell size  integral to membrane  apical plasma membrane  cerebellar Purkinje cell differentiation  cerebellar granule cell differentiation  PDZ domain binding  neuron differentiation  calcium-dependent ATPase activity  ion transmembrane transport  locomotion  serotonin metabolic process  neuronal cell body  otolith mineralization  cGMP metabolic process  metal ion binding  regulation of synaptic plasticity  synapse organization  neuromuscular process controlling balance  detection of mechanical stimulus involved in sensory perception of sound  cytosolic calcium ion homeostasis  positive regulation of calcium ion transport  transmembrane transport  auditory receptor cell stereocilium organization  cochlea development  
Ontology : EGO-EBIcalcium-transporting ATPase activity  calcium-transporting ATPase activity  calcium ion binding  protein binding  calmodulin binding  calmodulin binding  ATP binding  ATP binding  cytoplasm  endoplasmic reticulum  plasma membrane  plasma membrane  plasma membrane  cilium  transport  calcium ion transport  organelle organization  lactation  blood coagulation  sensory perception of sound  locomotory behavior  protein C-terminus binding  regulation of cell size  integral to membrane  apical plasma membrane  cerebellar Purkinje cell differentiation  cerebellar granule cell differentiation  PDZ domain binding  neuron differentiation  calcium-dependent ATPase activity  ion transmembrane transport  locomotion  serotonin metabolic process  neuronal cell body  otolith mineralization  cGMP metabolic process  metal ion binding  regulation of synaptic plasticity  synapse organization  neuromuscular process controlling balance  detection of mechanical stimulus involved in sensory perception of sound  cytosolic calcium ion homeostasis  positive regulation of calcium ion transport  transmembrane transport  auditory receptor cell stereocilium organization  cochlea development  
Pathways : KEGGCalcium signaling pathway    Adrenergic signaling in cardiomyocytes    Salivary secretion    Pancreatic secretion   
REACTOMEATP2B2
Protein Interaction DatabaseATP2B2
Wikipedia pathwaysATP2B2
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ATP2B2
SNP (GeneSNP Utah)ATP2B2
SNP : HGBaseATP2B2
Genetic variants : HAPMAPATP2B2
1000_GenomesATP2B2 
ICGC programENSG00000157087 
Somatic Mutations in Cancer : COSMICATP2B2 
CONAN: Copy Number AnalysisATP2B2 
Mutations and Diseases : HGMDATP2B2
OMIM108733    601386   
GENETestsATP2B2
Disease Genetic AssociationATP2B2
Huge Navigator ATP2B2 [HugePedia]  ATP2B2 [HugeCancerGEM]
Genomic VariantsATP2B2  ATP2B2 [DGVbeta]
Exome VariantATP2B2
dbVarATP2B2
ClinVarATP2B2
snp3D : Map Gene to Disease491
General knowledge
Homologs : HomoloGeneATP2B2
Homology/Alignments : Family Browser (UCSC)ATP2B2
Phylogenetic Trees/Animal Genes : TreeFamATP2B2
Chemical/Protein Interactions : CTD491
Chemical/Pharm GKB GenePA25108
Clinical trialATP2B2
Cancer Resource (Charite)ENSG00000157087
Other databases
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
CoreMineATP2B2
iHOPATP2B2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Mar 31 09:14:01 CEST 2014

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