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ATP4A (ATPase H+/K+ transporting alpha subunit)

Identity

Alias_namesATPase
Alias_symbol (synonym)ATP6A
Other alias
HGNC (Hugo) ATP4A
LocusID (NCBI) 495
Atlas_Id 53466
Location 19q13.12  [Link to chromosome band 19q13]
Location_base_pair Starts at 35550193 and ends at 35563658 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATP4A   819
Cards
Entrez_Gene (NCBI)ATP4A  495  ATPase H+/K+ transporting alpha subunit
AliasesATP6A
GeneCards (Weizmann)ATP4A
Ensembl hg19 (Hinxton)ENSG00000105675 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105675 [Gene_View]  chr19:35550193-35563658 [Contig_View]  ATP4A [Vega]
ICGC DataPortalENSG00000105675
TCGA cBioPortalATP4A
AceView (NCBI)ATP4A
Genatlas (Paris)ATP4A
WikiGenes495
SOURCE (Princeton)ATP4A
Genetics Home Reference (NIH)ATP4A
Genomic and cartography
GoldenPath hg38 (UCSC)ATP4A  -     chr19:35550193-35563658 -  19q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATP4A  -     19q13.12   [Description]    (hg19-Feb_2009)
EnsemblATP4A - 19q13.12 [CytoView hg19]  ATP4A - 19q13.12 [CytoView hg38]
Mapping of homologs : NCBIATP4A [Mapview hg19]  ATP4A [Mapview hg38]
OMIM137216   
Gene and transcription
Genbank (Entrez)AK058032 AK223259 AK308474 AL832971 BC167780
RefSeq transcript (Entrez)NM_000704
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATP4A
Cluster EST : UnigeneHs.36992 [ NCBI ]
CGAP (NCI)Hs.36992
Alternative Splicing GalleryENSG00000105675
Gene ExpressionATP4A [ NCBI-GEO ]   ATP4A [ EBI - ARRAY_EXPRESS ]   ATP4A [ SEEK ]   ATP4A [ MEM ]
Gene Expression Viewer (FireBrowse)ATP4A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)495
GTEX Portal (Tissue expression)ATP4A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20648   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20648  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20648
Splice isoforms : SwissVarP20648
Catalytic activity : Enzyme3.6.3.10 [ Enzyme-Expasy ]   3.6.3.103.6.3.10 [ IntEnz-EBI ]   3.6.3.10 [ BRENDA ]   3.6.3.10 [ KEGG ]   
PhosPhoSitePlusP20648
Domaine pattern : Prosite (Expaxy)ATPASE_E1_E2 (PS00154)   
Domains : Interpro (EBI)ATPase_P-typ_cation-transptr_C    ATPase_P-typ_cation-transptr_N    ATPase_P-typ_cyto_domN    ATPase_P-typ_H/K-transp_N    ATPase_P-typ_P_site    ATPase_P-typ_TM_dom    ATPase_P-typ_transduc_dom_A    HAD-like_dom    P-type_ATPase_IIC    P_typ_ATPase   
Domain families : Pfam (Sanger)Cation_ATPase_C (PF00689)    Cation_ATPase_N (PF00690)    E1-E2_ATPase (PF00122)    H-K_ATPase_N (PF09040)   
Domain families : Pfam (NCBI)pfam00689    pfam00690    pfam00122    pfam09040   
Domain families : Smart (EMBL)Cation_ATPase_N (SM00831)  
Conserved Domain (NCBI)ATP4A
DMDM Disease mutations495
Blocks (Seattle)ATP4A
SuperfamilyP20648
Human Protein AtlasENSG00000105675
Peptide AtlasP20648
HPRD00668
IPIIPI00218919   
Protein Interaction databases
DIP (DOE-UCLA)P20648
IntAct (EBI)P20648
FunCoupENSG00000105675
BioGRIDATP4A
STRING (EMBL)ATP4A
ZODIACATP4A
Ontologies - Pathways
QuickGOP20648
Ontology : AmiGOmagnesium ion binding  sodium:potassium-exchanging ATPase activity  ATP binding  extracellular space  plasma membrane  integral component of plasma membrane  transport  potassium ion transport  sodium ion transport  hydrogen:potassium-exchanging ATPase activity  establishment or maintenance of transmembrane electrochemical gradient  ATP hydrolysis coupled proton transport  ion transmembrane transport  
Ontology : EGO-EBImagnesium ion binding  sodium:potassium-exchanging ATPase activity  ATP binding  extracellular space  plasma membrane  integral component of plasma membrane  transport  potassium ion transport  sodium ion transport  hydrogen:potassium-exchanging ATPase activity  establishment or maintenance of transmembrane electrochemical gradient  ATP hydrolysis coupled proton transport  ion transmembrane transport  
Pathways : KEGGOxidative phosphorylation    Collecting duct acid secretion    Gastric acid secretion   
NDEx NetworkATP4A
Atlas of Cancer Signalling NetworkATP4A
Wikipedia pathwaysATP4A
Orthology - Evolution
OrthoDB495
GeneTree (enSembl)ENSG00000105675
Phylogenetic Trees/Animal Genes : TreeFamATP4A
HOVERGENP20648
HOGENOMP20648
Homologs : HomoloGeneATP4A
Homology/Alignments : Family Browser (UCSC)ATP4A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATP4A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATP4A
dbVarATP4A
ClinVarATP4A
1000_GenomesATP4A 
Exome Variant ServerATP4A
ExAC (Exome Aggregation Consortium)ATP4A (select the gene name)
Genetic variants : HAPMAP495
Genomic Variants (DGV)ATP4A [DGVbeta]
DECIPHERATP4A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATP4A 
Mutations
ICGC Data PortalATP4A 
TCGA Data PortalATP4A 
Broad Tumor PortalATP4A
OASIS PortalATP4A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATP4A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATP4A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATP4A
DgiDB (Drug Gene Interaction Database)ATP4A
DoCM (Curated mutations)ATP4A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATP4A (select a term)
intoGenATP4A
Cancer3DATP4A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137216   
Orphanet
MedgenATP4A
Genetic Testing Registry ATP4A
NextProtP20648 [Medical]
TSGene495
GENETestsATP4A
Target ValidationATP4A
Huge Navigator ATP4A [HugePedia]
snp3D : Map Gene to Disease495
BioCentury BCIQATP4A
ClinGenATP4A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD495
Chemical/Pharm GKB GenePA25113
Clinical trialATP4A
Miscellaneous
canSAR (ICR)ATP4A (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATP4A
EVEXATP4A
GoPubMedATP4A
iHOPATP4A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:47:33 CEST 2017

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