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ATP5L (ATP synthase, H+ transporting, mitochondrial Fo complex subunit G)

Identity

Alias_namesATP synthase, H transporting, mitochondrial F0 complex, subunit g
ATP synthase, H transporting, mitochondrial F0 complex, subunit G
ATP synthase, H transporting, mitochondrial Fo complex, subunit G
Alias_symbol (synonym)ATP5JG
Other alias
HGNC (Hugo) ATP5L
LocusID (NCBI) 10632
Atlas_Id 54142
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 118401389 and ends at 118409847 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP5L (11q23.3) / CUBN (10p13)ATP5L (11q23.3) / TEAD1 (11p15.3)SZT2 (1p34.2) / ATP5L (11q23.3)
TEAD1 (11p15.3) / ATP5L (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ATP5L   14247
Cards
Entrez_Gene (NCBI)ATP5L  10632  ATP synthase, H+ transporting, mitochondrial Fo complex subunit G
AliasesATP5JG
GeneCards (Weizmann)ATP5L
Ensembl hg19 (Hinxton)ENSG00000167283 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167283 [Gene_View]  chr11:118401389-118409847 [Contig_View]  ATP5L [Vega]
ICGC DataPortalENSG00000167283
TCGA cBioPortalATP5L
AceView (NCBI)ATP5L
Genatlas (Paris)ATP5L
WikiGenes10632
SOURCE (Princeton)ATP5L
Genetics Home Reference (NIH)ATP5L
Genomic and cartography
GoldenPath hg38 (UCSC)ATP5L  -     chr11:118401389-118409847 +  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATP5L  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblATP5L - 11q23.3 [CytoView hg19]  ATP5L - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBIATP5L [Mapview hg19]  ATP5L [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA258888 AF070655 AF087846 AF092124 AI337729
RefSeq transcript (Entrez)NM_006476
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATP5L
Cluster EST : UnigeneHs.486360 [ NCBI ]
CGAP (NCI)Hs.486360
Alternative Splicing GalleryENSG00000167283
Gene ExpressionATP5L [ NCBI-GEO ]   ATP5L [ EBI - ARRAY_EXPRESS ]   ATP5L [ SEEK ]   ATP5L [ MEM ]
Gene Expression Viewer (FireBrowse)ATP5L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10632
GTEX Portal (Tissue expression)ATP5L
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75964   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75964  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75964
Splice isoforms : SwissVarO75964
PhosPhoSitePlusO75964
Domains : Interpro (EBI)ATP_synth_F0_gsu_mt    ATP_synth_su_G_mt_met   
Domain families : Pfam (Sanger)ATP-synt_G (PF04718)   
Domain families : Pfam (NCBI)pfam04718   
Conserved Domain (NCBI)ATP5L
DMDM Disease mutations10632
Blocks (Seattle)ATP5L
SuperfamilyO75964
Human Protein AtlasENSG00000167283
Peptide AtlasO75964
HPRD09815
IPIIPI00027448   IPI00983379   
Protein Interaction databases
DIP (DOE-UCLA)O75964
IntAct (EBI)O75964
FunCoupENSG00000167283
BioGRIDATP5L
STRING (EMBL)ATP5L
ZODIACATP5L
Ontologies - Pathways
QuickGOO75964
Ontology : AmiGOmitochondrial proton-transporting ATP synthase complex, coupling factor F(o)  mitochondrion  mitochondrial inner membrane  mitochondrial proton-transporting ATP synthase complex  ATP biosynthetic process  ATP synthesis coupled proton transport  ATPase activity  transmembrane transporter activity  mitochondrial ATP synthesis coupled proton transport  mitochondrial ATP synthesis coupled proton transport  proton-transporting ATP synthase activity, rotational mechanism  extracellular exosome  ATP hydrolysis coupled cation transmembrane transport  
Ontology : EGO-EBImitochondrial proton-transporting ATP synthase complex, coupling factor F(o)  mitochondrion  mitochondrial inner membrane  mitochondrial proton-transporting ATP synthase complex  ATP biosynthetic process  ATP synthesis coupled proton transport  ATPase activity  transmembrane transporter activity  mitochondrial ATP synthesis coupled proton transport  mitochondrial ATP synthesis coupled proton transport  proton-transporting ATP synthase activity, rotational mechanism  extracellular exosome  ATP hydrolysis coupled cation transmembrane transport  
Pathways : KEGGOxidative phosphorylation   
NDEx NetworkATP5L
Atlas of Cancer Signalling NetworkATP5L
Wikipedia pathwaysATP5L
Orthology - Evolution
OrthoDB10632
GeneTree (enSembl)ENSG00000167283
Phylogenetic Trees/Animal Genes : TreeFamATP5L
HOVERGENO75964
HOGENOMO75964
Homologs : HomoloGeneATP5L
Homology/Alignments : Family Browser (UCSC)ATP5L
Gene fusions - Rearrangements
Fusion : MitelmanATP5L/TEAD1 [11q23.3/11p15.3]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATP5L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATP5L
dbVarATP5L
ClinVarATP5L
1000_GenomesATP5L 
Exome Variant ServerATP5L
ExAC (Exome Aggregation Consortium)ATP5L (select the gene name)
Genetic variants : HAPMAP10632
Genomic Variants (DGV)ATP5L [DGVbeta]
DECIPHERATP5L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATP5L 
Mutations
ICGC Data PortalATP5L 
TCGA Data PortalATP5L 
Broad Tumor PortalATP5L
OASIS PortalATP5L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATP5L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATP5L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ATP5L
DgiDB (Drug Gene Interaction Database)ATP5L
DoCM (Curated mutations)ATP5L (select the gene name)
CIViC (Clinical IntErpreda˘ions of Variants in Cancer)ATP5L (select a term)
intoGenATP5L
Cancer3DATP5L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenATP5L
Genetic Testing Registry ATP5L
NextProtO75964 [Medical]
TSGene10632
GENETestsATP5L
Target ValidationATP5L
Huge Navigator ATP5L [HugePedia]
snp3D : Map Gene to Disease10632
BioCentury BCIQATP5L
ClinGenATP5L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10632
Chemical/Pharm GKB GenePA25143
Clinical trialATP5L
Miscellaneous
canSAR (ICR)ATP5L (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATP5L
EVEXATP5L
GoPubMedATP5L
iHOPATP5L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 18:58:36 CEST 2017

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