Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ATP5O (ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit)

Identity

Alias_symbol (synonym)OSCP
ATPO
Other aliasHMC08D05
HGNC (Hugo) ATP5O
LocusID (NCBI) 539
Atlas_Id 52972
Location 21q22.11  [Link to chromosome band 21q22]
Location_base_pair Starts at 33903453 and ends at 33915854 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP5O (21q22.11) / CAP1 (1p34.2)RYK (3q22.2) / ATP5O (21q22.11)TIAM1 (21q22.11) / ATP5O (21q22.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATP5O   850
Cards
Entrez_Gene (NCBI)ATP5O  539  ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
AliasesATPO; HMC08D05; OSCP
GeneCards (Weizmann)ATP5O
Ensembl hg19 (Hinxton)ENSG00000241837 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000241837 [Gene_View]  chr21:33903453-33915854 [Contig_View]  ATP5O [Vega]
ICGC DataPortalENSG00000241837
TCGA cBioPortalATP5O
AceView (NCBI)ATP5O
Genatlas (Paris)ATP5O
WikiGenes539
SOURCE (Princeton)ATP5O
Genetics Home Reference (NIH)ATP5O
Genomic and cartography
GoldenPath hg38 (UCSC)ATP5O  -     chr21:33903453-33915854 -  21q22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATP5O  -     21q22.11   [Description]    (hg19-Feb_2009)
EnsemblATP5O - 21q22.11 [CytoView hg19]  ATP5O - 21q22.11 [CytoView hg38]
Mapping of homologs : NCBIATP5O [Mapview hg19]  ATP5O [Mapview hg38]
OMIM600828   
Gene and transcription
Genbank (Entrez)AF088071 AK093795 AK124187 AK222608 AK222962
RefSeq transcript (Entrez)NM_001697
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATP5O
Cluster EST : UnigeneHs.409140 [ NCBI ]
CGAP (NCI)Hs.409140
Alternative Splicing GalleryENSG00000241837
Gene ExpressionATP5O [ NCBI-GEO ]   ATP5O [ EBI - ARRAY_EXPRESS ]   ATP5O [ SEEK ]   ATP5O [ MEM ]
Gene Expression Viewer (FireBrowse)ATP5O [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)539
GTEX Portal (Tissue expression)ATP5O
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48047   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48047  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48047
Splice isoforms : SwissVarP48047
PhosPhoSitePlusP48047
Domaine pattern : Prosite (Expaxy)ATPASE_DELTA (PS00389)   
Domains : Interpro (EBI)ATP_synth_OSCP/delta_N    ATPase_OSCP/d_CS    ATPase_OSCP/dsu   
Domain families : Pfam (Sanger)OSCP (PF00213)   
Domain families : Pfam (NCBI)pfam00213   
Conserved Domain (NCBI)ATP5O
DMDM Disease mutations539
Blocks (Seattle)ATP5O
SuperfamilyP48047
Human Protein AtlasENSG00000241837
Peptide AtlasP48047
HPRD02899
IPIIPI00007611   IPI00878218   IPI00853134   IPI00878045   IPI00893479   
Protein Interaction databases
DIP (DOE-UCLA)P48047
IntAct (EBI)P48047
FunCoupENSG00000241837
BioGRIDATP5O
STRING (EMBL)ATP5O
ZODIACATP5O
Ontologies - Pathways
QuickGOP48047
Ontology : AmiGOtransporter activity  protein binding  nucleus  mitochondrion  mitochondrial inner membrane  mitochondrial proton-transporting ATP synthase complex  mitochondrial proton-transporting ATP synthase complex  plasma membrane  ATP biosynthetic process  ATP biosynthetic process  drug binding  proton transport  ATPase activity  ATPase activity  transmembrane transporter activity  extracellular matrix  mitochondrial ATP synthesis coupled proton transport  mitochondrial ATP synthesis coupled proton transport  proton-transporting ATP synthase activity, rotational mechanism  extracellular exosome  ATP hydrolysis coupled cation transmembrane transport  
Ontology : EGO-EBItransporter activity  protein binding  nucleus  mitochondrion  mitochondrial inner membrane  mitochondrial proton-transporting ATP synthase complex  mitochondrial proton-transporting ATP synthase complex  plasma membrane  ATP biosynthetic process  ATP biosynthetic process  drug binding  proton transport  ATPase activity  ATPase activity  transmembrane transporter activity  extracellular matrix  mitochondrial ATP synthesis coupled proton transport  mitochondrial ATP synthesis coupled proton transport  proton-transporting ATP synthase activity, rotational mechanism  extracellular exosome  ATP hydrolysis coupled cation transmembrane transport  
Pathways : KEGGOxidative phosphorylation    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkATP5O
Atlas of Cancer Signalling NetworkATP5O
Wikipedia pathwaysATP5O
Orthology - Evolution
OrthoDB539
GeneTree (enSembl)ENSG00000241837
Phylogenetic Trees/Animal Genes : TreeFamATP5O
HOVERGENP48047
HOGENOMP48047
Homologs : HomoloGeneATP5O
Homology/Alignments : Family Browser (UCSC)ATP5O
Gene fusions - Rearrangements
Fusion : MitelmanRYK/ATP5O [3q22.2/21q22.11]  [t(3;21)(q22;q22)]  
Fusion Cancer (Beijing)TIAM1 [21q22.11]  -  ATP5O [21q22.11]  [FUSC000179]  [FUSC000179]  [FUSC000179]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATP5O [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATP5O
dbVarATP5O
ClinVarATP5O
1000_GenomesATP5O 
Exome Variant ServerATP5O
ExAC (Exome Aggregation Consortium)ATP5O (select the gene name)
Genetic variants : HAPMAP539
Genomic Variants (DGV)ATP5O [DGVbeta]
DECIPHERATP5O [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATP5O 
Mutations
ICGC Data PortalATP5O 
TCGA Data PortalATP5O 
Broad Tumor PortalATP5O
OASIS PortalATP5O [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATP5O  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATP5O
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ATP5O
DgiDB (Drug Gene Interaction Database)ATP5O
DoCM (Curated mutations)ATP5O (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATP5O (select a term)
intoGenATP5O
Cancer3DATP5O(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600828   
Orphanet
MedgenATP5O
Genetic Testing Registry ATP5O
NextProtP48047 [Medical]
TSGene539
GENETestsATP5O
Huge Navigator ATP5O [HugePedia]
snp3D : Map Gene to Disease539
BioCentury BCIQATP5O
ClinGenATP5O
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD539
Chemical/Pharm GKB GenePA25144
Clinical trialATP5O
Miscellaneous
canSAR (ICR)ATP5O (select the gene name)
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATP5O
EVEXATP5O
GoPubMedATP5O
iHOPATP5O
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:07:11 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.