Alias (NCBI) | ATP6C |
| ATP6D |
| VATC |
| Vma5 |
HGNC (Hugo) |
ATP6V1C1 |
HGNC Alias symb | VATC |
| Vma5 |
HGNC Previous name | ATP6D |
| ATP6C |
HGNC Previous name | ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD |
| ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C, isoform 1 |
| ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
LocusID (NCBI) |
528 |
Atlas_Id |
45846 |
Location |
8q22.3 [Link to chromosome band 8q22] |
Location_base_pair |
Starts at 103021083 and ends at 103073051 bp from pter ( according to hg38-Dec_2013) |
| Nomenclature |
HGNC (Hugo) | ATP6V1C1 856 |
| Cards |
Entrez_Gene (NCBI) | ATP6V1C1 ATPase H+ transporting V1 subunit C1 |
Aliases | ATP6C; ATP6D; VATC; Vma5 |
GeneCards (Weizmann) | ATP6V1C1 |
Ensembl hg19 (Hinxton) | ENSG00000155097 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000155097 [Gene_View]  ENSG00000155097 [Sequence] chr8:103021083-103073051 [Contig_View] ATP6V1C1 [Vega] |
ICGC DataPortal | ENSG00000155097 |
TCGA cBioPortal | ATP6V1C1 |
AceView (NCBI) | ATP6V1C1 |
Genatlas (Paris) | ATP6V1C1 |
SOURCE (Princeton) | ATP6V1C1 |
Genetics Home Reference (NIH) | ATP6V1C1 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | ATP6V1C1 - chr8:103021083-103073051 + 8q22.3 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | ATP6V1C1 - 8q22.3 [Description] (hg19-Feb_2009) |
GoldenPath | ATP6V1C1 - 8q22.3 [CytoView hg19] ATP6V1C1 - 8q22.3 [CytoView hg38] |
ImmunoBase | ENSG00000155097 |
genome Data Viewer NCBI | ATP6V1C1 [Mapview hg19] |
OMIM | 603097 |
| Gene and transcription |
Genbank (Entrez) | AA242944 AK000064 AK090702 AK298617 AK308632 |
RefSeq transcript (Entrez) | NM_001007254 NM_001695 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | ATP6V1C1 |
Alternative Splicing Gallery | ENSG00000155097 |
Gene Expression | ATP6V1C1 [ NCBI-GEO ] ATP6V1C1 [ EBI - ARRAY_EXPRESS ]
ATP6V1C1 [ SEEK ] ATP6V1C1 [ MEM ] |
Gene Expression Viewer (FireBrowse) | ATP6V1C1 [ Firebrowse - Broad ] |
Genevisible | Expression of ATP6V1C1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 528 |
GTEX Portal (Tissue expression) | ATP6V1C1 |
Human Protein Atlas | ENSG00000155097-ATP6V1C1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | P21283 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | P21283 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | P21283 |
Splice isoforms : SwissVar | P21283 |
PhosPhoSitePlus | P21283 |
Domains : Interpro (EBI) | ATPase_V1-cplx_csu Vac_ATP_synth_c_sf |
Domain families : Pfam (Sanger) | V-ATPase_C (PF03223) |
Domain families : Pfam (NCBI) | pfam03223 |
Conserved Domain (NCBI) | ATP6V1C1 |
Blocks (Seattle) | ATP6V1C1 |
Superfamily | P21283 |
Human Protein Atlas [tissue] | ENSG00000155097-ATP6V1C1 [tissue] |
Peptide Atlas | P21283 |
HPRD | 04371 |
IPI | IPI00007814 IPI00976996 IPI00983141 |
| Protein Interaction databases |
DIP (DOE-UCLA) | P21283 |
IntAct (EBI) | P21283 |
BioGRID | ATP6V1C1 |
STRING (EMBL) | ATP6V1C1 |
ZODIAC | ATP6V1C1 |
| Ontologies - Pathways |
QuickGO | P21283 |
Ontology : AmiGO | vacuolar proton-transporting V-type ATPase, V1 domain transporter activity protein binding lysosomal membrane cytosol plasma membrane insulin receptor signaling pathway proton-exporting ATPase activity, phosphorylative mechanism regulation of macroautophagy proton-transporting two-sector ATPase complex cytoplasmic vesicle transferrin transport ion transmembrane transport apical part of cell proton-transporting ATPase activity, rotational mechanism extracellular exosome phagosome acidification proton transmembrane transport |
Ontology : EGO-EBI | vacuolar proton-transporting V-type ATPase, V1 domain transporter activity protein binding lysosomal membrane cytosol plasma membrane insulin receptor signaling pathway proton-exporting ATPase activity, phosphorylative mechanism regulation of macroautophagy proton-transporting two-sector ATPase complex cytoplasmic vesicle transferrin transport ion transmembrane transport apical part of cell proton-transporting ATPase activity, rotational mechanism extracellular exosome phagosome acidification proton transmembrane transport |
Pathways : KEGG | Oxidative phosphorylation Phagosome Synaptic vesicle cycle Collecting duct acid secretion Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection Rheumatoid arthritis |
NDEx Network | ATP6V1C1 |
Atlas of Cancer Signalling Network | ATP6V1C1 |
Wikipedia pathways | ATP6V1C1 |
| Orthology - Evolution |
OrthoDB | 528 |
GeneTree (enSembl) | ENSG00000155097 |
Phylogenetic Trees/Animal Genes : TreeFam | ATP6V1C1 |
HOGENOM | P21283 |
Homologs : HomoloGene | ATP6V1C1 |
Homology/Alignments : Family Browser (UCSC) | ATP6V1C1 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | AZIN1/ATP6V1C1 [8q22.3/8q22.3]   |
Fusion : Mitelman | GBA2/ATP6V1C1 [9p13.3/8q22.3]   |
Fusion : Mitelman | RIMS2/ATP6V1C1 [8q22.3/8q22.3]   |
Fusion Portal | AZIN1 8q22.3 ATP6V1C1 8q22.3 SKCM |
Fusion Portal | GBA2 9p13.3 ATP6V1C1 8q22.3 BRCA |
Fusion : Quiver | ATP6V1C1 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | ATP6V1C1 [hg38] |
dbVar | ATP6V1C1 |
ClinVar | ATP6V1C1 |
Monarch | ATP6V1C1 |
1000_Genomes | ATP6V1C1 |
Exome Variant Server | ATP6V1C1 |
GNOMAD Browser | ENSG00000155097 |
Varsome Browser | ATP6V1C1 |
Genomic Variants (DGV) | ATP6V1C1 [DGVbeta] |
DECIPHER | ATP6V1C1 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | ATP6V1C1 |
| Mutations |
ICGC Data Portal | ATP6V1C1 |
TCGA Data Portal | ATP6V1C1 |
Broad Tumor Portal | ATP6V1C1 |
OASIS Portal | ATP6V1C1 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | ATP6V1C1 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | ATP6V1C1 |
Mutations and Diseases : HGMD | ATP6V1C1 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search ATP6V1C1 |
DgiDB (Drug Gene Interaction Database) | ATP6V1C1 |
DoCM (Curated mutations) | ATP6V1C1 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | ATP6V1C1 (select a term) |
intoGen | ATP6V1C1 |
Cancer3D | ATP6V1C1(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 603097 |
Orphanet | |
DisGeNET | ATP6V1C1 |
Medgen | ATP6V1C1 |
Genetic Testing Registry | ATP6V1C1
|
NextProt | P21283 [Medical] |
GENETests | ATP6V1C1 |
Target Validation | ATP6V1C1 |
Huge Navigator |
ATP6V1C1 [HugePedia] |
ClinGen | ATP6V1C1 |
| Clinical trials, drugs, therapy |
---|
MyCancerGenome | ATP6V1C1 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA25156 |
Pharos | P21283 |
Clinical trial | ATP6V1C1 |
| Miscellaneous |
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canSAR (ICR) | ATP6V1C1 (select the gene name) |
Harmonizome | ATP6V1C1 |
DataMed Index | ATP6V1C1 |
| Probes |
---|
| Litterature |
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PubMed | 44 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | ATP6V1C1 |