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ATP8A2 (ATPase, aminophospholipid transporter-like, class I, type 8A, member 2)

Identity

Other namesATP
ATPIB
DKFZp434B1913
IB
ML-1
HGNC (Hugo) ATP8A2
Location 13q12.13
Location_base_pair Starts at 24844209 and ends at 25493420 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ATP8A2   13533
Entrez_Gene (NCBI)ATP8A2  51761  ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
Cards
GeneCards (Weizmann)ATP8A2
Ensembl (Hinxton)ENSG00000132932 [Gene_View]  ATP8A2 [Vega]
AceView (NCBI)ATP8A2
Genatlas (Paris)ATP8A2
euGene (Indiana)51761
SOURCE (Stanford)NM_016529
Gene Expression (Array Express) ENSG00000132932
Genomic and cartography
GoldenPath (UCSC)ATP8A2  -  13q12.13   chr13:24844209-25493420 +  13q12.13   [Description]    (hg18-March_2006)
EnsemblATP8A2 - 13q12.13 [CytoView]
Mapping of homologs : NCBIATP8A2 [Mapview]
OMIM605870   
Gene and transcription
Gene : Genbank (Entrez)AF236871 AK094653 AK126031 AK127263 AK302980
Reference sequence (RefSeq transcript) :SRSNM_016529
Reference transcript : EntrezNM_016529
RefSeq genomic : SRSAC_000056 AC_000145 NC_000013 NT_024524 NW_001838070 NW_925473
RefSeq genomic : EntrezAC_000056 AC_000145 NC_000013 NT_024524 NW_001838070 NW_925473
Consensus coding sequences : CCDS NCBIATP8A2
Cluster EST : UnigeneHs.444957 [ SRS ] Hs.444957 [ NCBI ]
Alternative Splicing : Fast-db (Paris)1399
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtQ9NTI2 (SRS) Q9NTI2 (Expasy) Q9NTI2 (Uniprot)
With graphics : InterProQ9NTI2
Splice isoforms : VarSplice FASTAQ9NTI2(VarSplice FASTA)
Domaine pattern : Prosite (SRS)ATPASE_E1_E2 (PS00154)   
Domain pattern : Prosite (Expaxy)ATPASE_E1_E2 (PS00154)   
Domains : Interpro (SRS)ATPase_P-typ_ATPase-assoc-dom    ATPase_P-typ_ion-transptr    ATPase_P-typ_P_site    ATPase_P-typ_Plipid-transl   
Domains : Interpro (EBI)ATPase_P-typ_ATPase-assoc-dom    ATPase_P-typ_ion-transptr    ATPase_P-typ_P_site    ATPase_P-typ_Plipid-transl   
Related proteins : CluSTrQ9NTI2
Domain families : Pfam SRSE1-E2_ATPase (PF00122)   
Domain families : Pfam SangerE1-E2_ATPase (PF00122)   
Domain families : Pfam NCBIpfam00122   
Blocks (Seattle)Q9NTI2
Crystal structure of protein : PDB SRS
Crystal structure of protein : PDBSum
Crystal structure of protein : IMB
Crystal structure of protein : PDB RSDB
HPRD05795
Protein Interaction databases
DIP (DOE-UCLA)Q9NTI2
IntAct (EBI)Q9NTI2
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBIATP8A2
SNP : GeneSNP UtahATP8A2
SNP : HGBaseATP8A2
Genetic variants : HAPMAPATP8A2
Mutations and Diseases : HGMDATP8A2
Hereditary diseases : OMIM605870   
Hereditary diseases : GENETests605870   
Diseases : Genetic AssociationATP8A2
General knowledge
Homologs : HomoloGeneATP8A2
Homology/Alignments : Family Browser UCSCATP8A2
Phylogenetic Trees/Animal Genes : TreeFamATP8A2
Catalytic activity : Enzyme3.6.3.1 [ Enzyme-Expasy ]   3.6.3.1 [ Enzyme-SRS ]   3.6.3.1 [ IntEnz-EBI ]   3.6.3.1 [ BRENDA ]   3.6.3.1 [ KEGG ]   
Chemical/Protein Interactions : CTD51761
Keywords Ontology : AmiGOnucleotide binding  magnesium ion binding  phospholipid-translocating ATPase activity  ATP binding  ATP biosynthetic process  negative regulation of cell proliferation  ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism  phospholipid transport  membrane  integral to membrane  hydrolase activity  hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances  
Keywords Ontology : EGO-EBInucleotide binding  magnesium ion binding  phospholipid-translocating ATPase activity  ATP binding  ATP biosynthetic process  negative regulation of cell proliferation  ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism  phospholipid transport  membrane  integral to membrane  hydrolase activity  hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances  
Pathways : BIOCARTA
Pathways : KEGG
Other databases
Probes
Probes : ImagenesATP8A2 Related clones (RZPD - Berlin)
Literature
PubMed6 Pubmed reference(s) in Entrez
PubGeneATP8A2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:29:17 CET 2010

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