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ATP8B2 (ATPase phospholipid transporting 8B2)

Identity

Alias_namesATPase, class I, type 8B, member 2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
Alias_symbol (synonym)ATPID
KIAA1137
Other alias
HGNC (Hugo) ATP8B2
LocusID (NCBI) 57198
Atlas_Id 53946
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 154298036 and ends at 154310322 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
IL6R (1q21.3) / ATP8B2 (1q21.3)IL6R 1q21.3 / ATP8B2 1q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ATP8B2   13534
Cards
Entrez_Gene (NCBI)ATP8B2  57198  ATPase phospholipid transporting 8B2
AliasesATPID
GeneCards (Weizmann)ATP8B2
Ensembl hg19 (Hinxton)ENSG00000143515 [Gene_View]  chr1:154298036-154310322 [Contig_View]  ATP8B2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143515 [Gene_View]  chr1:154298036-154310322 [Contig_View]  ATP8B2 [Vega]
ICGC DataPortalENSG00000143515
TCGA cBioPortalATP8B2
AceView (NCBI)ATP8B2
Genatlas (Paris)ATP8B2
WikiGenes57198
SOURCE (Princeton)ATP8B2
Genetics Home Reference (NIH)ATP8B2
Genomic and cartography
GoldenPath hg19 (UCSC)ATP8B2  -     chr1:154298036-154310322 +  1q21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ATP8B2  -     1q21.3   [Description]    (hg38-Dec_2013)
EnsemblATP8B2 - 1q21.3 [CytoView hg19]  ATP8B2 - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBIATP8B2 [Mapview hg19]  ATP8B2 [Mapview hg38]
OMIM605867   
Gene and transcription
Genbank (Entrez)AB032963 AI857468 AK054886 AK304806 AL137537
RefSeq transcript (Entrez)NM_001005855 NM_020452
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)ATP8B2
Cluster EST : UnigeneHs.435700 [ NCBI ]
CGAP (NCI)Hs.435700
Alternative Splicing GalleryENSG00000143515
Gene ExpressionATP8B2 [ NCBI-GEO ]   ATP8B2 [ EBI - ARRAY_EXPRESS ]   ATP8B2 [ SEEK ]   ATP8B2 [ MEM ]
Gene Expression Viewer (FireBrowse)ATP8B2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57198
GTEX Portal (Tissue expression)ATP8B2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP98198   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP98198  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP98198
Splice isoforms : SwissVarP98198
Catalytic activity : Enzyme3.6.3.1 [ Enzyme-Expasy ]   3.6.3.13.6.3.1 [ IntEnz-EBI ]   3.6.3.1 [ BRENDA ]   3.6.3.1 [ KEGG ]   
PhosPhoSitePlusP98198
Domaine pattern : Prosite (Expaxy)ATPASE_E1_E2 (PS00154)   
Domains : Interpro (EBI)ATP8B2    ATPase_P-typ_cyto_domN    ATPase_P-typ_P_site    ATPase_P-typ_transduc_dom_A    HAD-like_dom    P-type_ATPase_IV    P-type_ATPase_N    P_typ_ATPase    P_typ_ATPase_c   
Domain families : Pfam (Sanger)E1-E2_ATPase (PF00122)    PhoLip_ATPase_C (PF16212)    PhoLip_ATPase_N (PF16209)   
Domain families : Pfam (NCBI)pfam00122    pfam16212    pfam16209   
Conserved Domain (NCBI)ATP8B2
DMDM Disease mutations57198
Blocks (Seattle)ATP8B2
SuperfamilyP98198
Human Protein AtlasENSG00000143515
Peptide AtlasP98198
HPRD05794
IPIIPI00396074   IPI00258027   IPI00844415   IPI00431800   
Protein Interaction databases
DIP (DOE-UCLA)P98198
IntAct (EBI)P98198
FunCoupENSG00000143515
BioGRIDATP8B2
STRING (EMBL)ATP8B2
ZODIACATP8B2
Ontologies - Pathways
QuickGOP98198
Ontology : AmiGOmagnesium ion binding  phospholipid-translocating ATPase activity  phospholipid-translocating ATPase activity  ATP binding  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  plasma membrane  Golgi organization  metabolic process  integral component of membrane  ion transmembrane transport  phospholipid translocation  phospholipid translocation  phospholipid translocation  
Ontology : EGO-EBImagnesium ion binding  phospholipid-translocating ATPase activity  phospholipid-translocating ATPase activity  ATP binding  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  plasma membrane  Golgi organization  metabolic process  integral component of membrane  ion transmembrane transport  phospholipid translocation  phospholipid translocation  phospholipid translocation  
NDEx NetworkATP8B2
Atlas of Cancer Signalling NetworkATP8B2
Wikipedia pathwaysATP8B2
Orthology - Evolution
OrthoDB57198
GeneTree (enSembl)ENSG00000143515
Phylogenetic Trees/Animal Genes : TreeFamATP8B2
HOVERGENP98198
HOGENOMP98198
Homologs : HomoloGeneATP8B2
Homology/Alignments : Family Browser (UCSC)ATP8B2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATP8B2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ATP8B2
dbVarATP8B2
ClinVarATP8B2
1000_GenomesATP8B2 
Exome Variant ServerATP8B2
ExAC (Exome Aggregation Consortium)ATP8B2 (select the gene name)
Genetic variants : HAPMAP57198
Genomic Variants (DGV)ATP8B2 [DGVbeta]
DECIPHER (Syndromes)1:154298036-154310322  ENSG00000143515
CONAN: Copy Number AnalysisATP8B2 
Mutations
ICGC Data PortalATP8B2 
TCGA Data PortalATP8B2 
Broad Tumor PortalATP8B2
OASIS PortalATP8B2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATP8B2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDATP8B2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATP8B2
DgiDB (Drug Gene Interaction Database)ATP8B2
DoCM (Curated mutations)ATP8B2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATP8B2 (select a term)
intoGenATP8B2
Cancer3DATP8B2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605867   
Orphanet
MedgenATP8B2
Genetic Testing Registry ATP8B2
NextProtP98198 [Medical]
TSGene57198
GENETestsATP8B2
Huge Navigator ATP8B2 [HugePedia]
snp3D : Map Gene to Disease57198
BioCentury BCIQATP8B2
ClinGenATP8B2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57198
Chemical/Pharm GKB GenePA25167
Clinical trialATP8B2
Miscellaneous
canSAR (ICR)ATP8B2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineATP8B2
EVEXATP8B2
GoPubMedATP8B2
iHOPATP8B2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:53:31 CEST 2017

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