Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10079
MIM: 609126
HGNC: 13540
Ensembl: ENSG00000054793
Variants:
dbSNP: 10079
ClinVar: 10079
TCGA: ENSG00000054793
COSMIC: ATP9A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000054793 | ENST00000311637 | A0A0A0MR22 |
| ENSG00000054793 | ENST00000338821 | O75110 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transmembrane transport of small molecules | REACTOME | R-HSA-382551 |
| Ion channel transport | REACTOME | R-HSA-983712 |
| Ion transport by P-type ATPases | REACTOME | R-HSA-936837 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36715683 | 2023 | The phospholipid flippase ATP9A enhances macropinocytosis to promote nutrient starvation tolerance in hepatocellular carcinoma. | 3 |
| 38049814 | 2023 | Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization. | 2 |
| 36715683 | 2023 | The phospholipid flippase ATP9A enhances macropinocytosis to promote nutrient starvation tolerance in hepatocellular carcinoma. | 3 |
| 38049814 | 2023 | Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization. | 2 |
| 34379057 | 2022 | Biallelic truncating variants in ATP9A cause a novel neurodevelopmental disorder involving postnatal microcephaly and failure to thrive. | 7 |
| 34379057 | 2022 | Biallelic truncating variants in ATP9A cause a novel neurodevelopmental disorder involving postnatal microcephaly and failure to thrive. | 7 |
| 34645814 | 2021 | Structural basis of the P4B ATPase lipid flippase activity. | 9 |
| 34645814 | 2021 | Structural basis of the P4B ATPase lipid flippase activity. | 9 |
| 33178388 | 2020 | Effects of ATP9A on Extracellular Vesicle Release and Exosomal Lipid Composition. | 8 |
| 33178388 | 2020 | Effects of ATP9A on Extracellular Vesicle Release and Exosomal Lipid Composition. | 8 |
| 30947313 | 2019 | The P4-ATPase ATP9A is a novel determinant of exosome release. | 20 |
| 30947313 | 2019 | The P4-ATPase ATP9A is a novel determinant of exosome release. | 20 |
| 30213940 | 2018 | SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion. | 37 |
| 30213940 | 2018 | SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion. | 37 |
| 26240149 | 2015 | Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETION. | 14 |
Citation
Dessen P
ATP9A (ATPase phospholipid transporting 9A (putative))
Atlas Genet Cytogenet Oncol Haematol. 2011-10-01
Online version: http://atlasgeneticsoncology.org/gene/52437/atp9a
