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ATP9B (ATPase phospholipid transporting 9B (putative))

Identity

Alias (NCBI)ATPASEP
ATPIIB
HUSSY-20
NEO1L
hMMR1
HGNC (Hugo) ATP9B
HGNC Alias symbATPIIB
HGNC Previous nameATPase, class II, type 9B
LocusID (NCBI) 374868
Atlas_Id 52429
Location 18q23  [Link to chromosome band 18q23]
Location_base_pair Starts at 79069394 and ends at 79378282 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATP9B (18q23) / ATP9B (18q23)ATP9B (18q23) / STK10 (5q35.1)ATP9B (18q23) / ZNF516 (18q23)
BCL3 (19q13.32) / ATP9B (18q23)BCL3 19q13.32 / ATP9B 18q23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(18;19)(q23;q13) BCL3/ATP9B

External links

Nomenclature
HGNC (Hugo)ATP9B   13541
Cards
Entrez_Gene (NCBI)ATP9B    ATPase phospholipid transporting 9B (putative)
AliasesATPASEP; ATPIIB; HUSSY-20; NEO1L; 
hMMR1
GeneCards (Weizmann)ATP9B
Ensembl hg19 (Hinxton)ENSG00000166377 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166377 [Gene_View]  ENSG00000166377 [Sequence]  chr18:79069394-79378282 [Contig_View]  ATP9B [Vega]
ICGC DataPortalENSG00000166377
TCGA cBioPortalATP9B
AceView (NCBI)ATP9B
Genatlas (Paris)ATP9B
SOURCE (Princeton)ATP9B
Genetics Home Reference (NIH)ATP9B
Genomic and cartography
GoldenPath hg38 (UCSC)ATP9B  -     chr18:79069394-79378282 +  18q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ATP9B  -     18q23   [Description]    (hg19-Feb_2009)
GoldenPathATP9B - 18q23 [CytoView hg19]  ATP9B - 18q23 [CytoView hg38]
ImmunoBaseENSG00000166377
genome Data Viewer NCBIATP9B [Mapview hg19]  
OMIM614446   
Gene and transcription
Genbank (Entrez)AB373110 AJ006268 AK093704 AK097757 AK127634
RefSeq transcript (Entrez)NM_001306085 NM_198531
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ATP9B
Alternative Splicing GalleryENSG00000166377
Gene ExpressionATP9B [ NCBI-GEO ]   ATP9B [ EBI - ARRAY_EXPRESS ]   ATP9B [ SEEK ]   ATP9B [ MEM ]
Gene Expression Viewer (FireBrowse)ATP9B [ Firebrowse - Broad ]
GenevisibleExpression of ATP9B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)374868
GTEX Portal (Tissue expression)ATP9B
Human Protein AtlasENSG00000166377-ATP9B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43861   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43861  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43861
Splice isoforms : SwissVarO43861
Catalytic activity : Enzyme7.6.2.1 [ Enzyme-Expasy ]   7.6.2.17.6.2.1 [ IntEnz-EBI ]   7.6.2.1 [ BRENDA ]   7.6.2.1 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusO43861
Domaine pattern : Prosite (Expaxy)ATPASE_E1_E2 (PS00154)   
Domains : Interpro (EBI)ATP9B    ATPase_P-typ_cyto_dom_N    ATPase_P-typ_P_site    ATPase_P-typ_TM_dom_sf    ATPase_P-typ_transduc_dom_A_sf    HAD-like_sf    HAD_sf    P-type_ATPase_IV    P-type_ATPase_N    P_typ_ATPase    P_typ_ATPase_c   
Domain families : Pfam (Sanger)PhoLip_ATPase_C (PF16212)    PhoLip_ATPase_N (PF16209)   
Domain families : Pfam (NCBI)pfam16212    pfam16209   
Conserved Domain (NCBI)ATP9B
Blocks (Seattle)ATP9B
SuperfamilyO43861
Human Protein Atlas [tissue]ENSG00000166377-ATP9B [tissue]
Peptide AtlasO43861
HPRD16528
IPIIPI00396022   IPI00479667   IPI00874118   IPI00902910   IPI00384996   IPI01010976   IPI00442422   IPI00442551   IPI00443388   IPI01011419   IPI00443934   IPI00985333   
Protein Interaction databases
DIP (DOE-UCLA)O43861
IntAct (EBI)O43861
BioGRIDATP9B
STRING (EMBL)ATP9B
ZODIACATP9B
Ontologies - Pathways
QuickGOO43861
Ontology : AmiGOmagnesium ion binding  ATP binding  endosome  trans-Golgi network  trans-Golgi network  plasma membrane  retrograde vesicle-mediated transport, Golgi to ER  endocytosis  integral component of membrane  phospholipid translocation  phospholipid translocation  perinuclear region of cytoplasm  
Ontology : EGO-EBImagnesium ion binding  ATP binding  endosome  trans-Golgi network  trans-Golgi network  plasma membrane  retrograde vesicle-mediated transport, Golgi to ER  endocytosis  integral component of membrane  phospholipid translocation  phospholipid translocation  perinuclear region of cytoplasm  
NDEx NetworkATP9B
Atlas of Cancer Signalling NetworkATP9B
Wikipedia pathwaysATP9B
Orthology - Evolution
OrthoDB374868
GeneTree (enSembl)ENSG00000166377
Phylogenetic Trees/Animal Genes : TreeFamATP9B
HOGENOMO43861
Homologs : HomoloGeneATP9B
Homology/Alignments : Family Browser (UCSC)ATP9B
Gene fusions - Rearrangements
Fusion : MitelmanBCL3/ATP9B [19q13.32/18q23]  
Fusion PortalBCL3 19q13.32 ATP9B 18q23 BRCA
Fusion : QuiverATP9B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerATP9B [hg38]
dbVarATP9B
ClinVarATP9B
MonarchATP9B
1000_GenomesATP9B 
Exome Variant ServerATP9B
GNOMAD BrowserENSG00000166377
Varsome BrowserATP9B
Genomic Variants (DGV)ATP9B [DGVbeta]
DECIPHERATP9B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisATP9B 
Mutations
ICGC Data PortalATP9B 
TCGA Data PortalATP9B 
Broad Tumor PortalATP9B
OASIS PortalATP9B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICATP9B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DATP9B
Mutations and Diseases : HGMDATP9B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ATP9B
DgiDB (Drug Gene Interaction Database)ATP9B
DoCM (Curated mutations)ATP9B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ATP9B (select a term)
intoGenATP9B
Cancer3DATP9B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614446   
Orphanet
DisGeNETATP9B
MedgenATP9B
Genetic Testing Registry ATP9B
NextProtO43861 [Medical]
GENETestsATP9B
Target ValidationATP9B
Huge Navigator ATP9B [HugePedia]
ClinGenATP9B
Clinical trials, drugs, therapy
MyCancerGenomeATP9B
Protein Interactions : CTD
Pharm GKB GenePA25172
PharosO43861
Clinical trialATP9B
Miscellaneous
canSAR (ICR)ATP9B (select the gene name)
HarmonizomeATP9B
DataMed IndexATP9B
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXATP9B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:06:43 CET 2021
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