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AUH (AU RNA binding methylglutaconyl-CoA hydratase)

Identity

Alias_namesAU RNA-binding protein/enoyl-Coenzyme A hydratase
AU RNA binding protein/enoyl-Coenzyme A hydratase
AU RNA binding protein/enoyl-CoA hydratase
Other alias-
HGNC (Hugo) AUH
LocusID (NCBI) 549
Atlas_Id 60664
Location 9q22.31  [Link to chromosome band 9q22]
Location_base_pair Starts at 91213815 and ends at 91361969 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CDC14B (9q22.32) / AUH (9q22.31)SPTAN1 (9q34.11) / AUH (9q22.31)SPTAN1 AUH
CDC14B AUH

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AUH   890
LRG (Locus Reference Genomic)LRG_449
Cards
Entrez_Gene (NCBI)AUH  549  AU RNA binding methylglutaconyl-CoA hydratase
Aliases
GeneCards (Weizmann)AUH
Ensembl hg19 (Hinxton)ENSG00000148090 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148090 [Gene_View]  chr9:91213815-91361969 [Contig_View]  AUH [Vega]
ICGC DataPortalENSG00000148090
TCGA cBioPortalAUH
AceView (NCBI)AUH
Genatlas (Paris)AUH
WikiGenes549
SOURCE (Princeton)AUH
Genetics Home Reference (NIH)AUH
Genomic and cartography
GoldenPath hg38 (UCSC)AUH  -     chr9:91213815-91361969 -  9q22.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AUH  -     9q22.31   [Description]    (hg19-Feb_2009)
EnsemblAUH - 9q22.31 [CytoView hg19]  AUH - 9q22.31 [CytoView hg38]
Mapping of homologs : NCBIAUH [Mapview hg19]  AUH [Mapview hg38]
OMIM250950   600529   
Gene and transcription
Genbank (Entrez)AK124142 AK302453 AM393420 AV751432 BC020722
RefSeq transcript (Entrez)NM_001306190 NM_001698
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AUH
Cluster EST : UnigeneHs.175905 [ NCBI ]
CGAP (NCI)Hs.175905
Alternative Splicing GalleryENSG00000148090
Gene ExpressionAUH [ NCBI-GEO ]   AUH [ EBI - ARRAY_EXPRESS ]   AUH [ SEEK ]   AUH [ MEM ]
Gene Expression Viewer (FireBrowse)AUH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)549
GTEX Portal (Tissue expression)AUH
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13825   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13825  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13825
Splice isoforms : SwissVarQ13825
Catalytic activity : Enzyme4.2.1.18 [ Enzyme-Expasy ]   4.2.1.184.2.1.18 [ IntEnz-EBI ]   4.2.1.18 [ BRENDA ]   4.2.1.18 [ KEGG ]   
PhosPhoSitePlusQ13825
Domaine pattern : Prosite (Expaxy)ENOYL_COA_HYDRATASE (PS00166)   
Domains : Interpro (EBI)ClpP/crotonase-like_dom    Crontonase_C    Crotonase_core_superfam    Enoyl-CoA_hyd/isom_CS   
Domain families : Pfam (Sanger)ECH_1 (PF00378)   
Domain families : Pfam (NCBI)pfam00378   
Conserved Domain (NCBI)AUH
DMDM Disease mutations549
Blocks (Seattle)AUH
PDB (SRS)1HZD    2ZQQ    2ZQR   
PDB (PDBSum)1HZD    2ZQQ    2ZQR   
PDB (IMB)1HZD    2ZQQ    2ZQR   
PDB (RSDB)1HZD    2ZQQ    2ZQR   
Structural Biology KnowledgeBase1HZD    2ZQQ    2ZQR   
SCOP (Structural Classification of Proteins)1HZD    2ZQQ    2ZQR   
CATH (Classification of proteins structures)1HZD    2ZQQ    2ZQR   
SuperfamilyQ13825
Human Protein AtlasENSG00000148090
Peptide AtlasQ13825
HPRD08987
IPIIPI00017802   IPI00102904   IPI00908429   
Protein Interaction databases
DIP (DOE-UCLA)Q13825
IntAct (EBI)Q13825
FunCoupENSG00000148090
BioGRIDAUH
STRING (EMBL)AUH
ZODIACAUH
Ontologies - Pathways
QuickGOQ13825
Ontology : AmiGOmRNA 3'-UTR binding  enoyl-CoA hydratase activity  methylglutaconyl-CoA hydratase activity  mitochondrion  mitochondrion  mitochondrial matrix  leucine catabolic process  fatty acid beta-oxidation  branched-chain amino acid catabolic process  
Ontology : EGO-EBImRNA 3'-UTR binding  enoyl-CoA hydratase activity  methylglutaconyl-CoA hydratase activity  mitochondrion  mitochondrion  mitochondrial matrix  leucine catabolic process  fatty acid beta-oxidation  branched-chain amino acid catabolic process  
Pathways : KEGGValine, leucine and isoleucine degradation   
NDEx NetworkAUH
Atlas of Cancer Signalling NetworkAUH
Wikipedia pathwaysAUH
Orthology - Evolution
OrthoDB549
GeneTree (enSembl)ENSG00000148090
Phylogenetic Trees/Animal Genes : TreeFamAUH
HOVERGENQ13825
HOGENOMQ13825
Homologs : HomoloGeneAUH
Homology/Alignments : Family Browser (UCSC)AUH
Gene fusions - Rearrangements
Fusion: TCGASPTAN1 AUH
Fusion: TCGACDC14B AUH
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAUH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AUH
dbVarAUH
ClinVarAUH
1000_GenomesAUH 
Exome Variant ServerAUH
ExAC (Exome Aggregation Consortium)AUH (select the gene name)
Genetic variants : HAPMAP549
Genomic Variants (DGV)AUH [DGVbeta]
DECIPHERAUH [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAUH 
Mutations
ICGC Data PortalAUH 
TCGA Data PortalAUH 
Broad Tumor PortalAUH
OASIS PortalAUH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAUH  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAUH
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch AUH
DgiDB (Drug Gene Interaction Database)AUH
DoCM (Curated mutations)AUH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AUH (select a term)
intoGenAUH
Cancer3DAUH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM250950    600529   
Orphanet10906   
MedgenAUH
Genetic Testing Registry AUH
NextProtQ13825 [Medical]
TSGene549
GENETestsAUH
Target ValidationAUH
Huge Navigator AUH [HugePedia]
snp3D : Map Gene to Disease549
BioCentury BCIQAUH
ClinGenAUH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD549
Chemical/Pharm GKB GenePA25181
Clinical trialAUH
Miscellaneous
canSAR (ICR)AUH (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAUH
EVEXAUH
GoPubMedAUH
iHOPAUH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:39:19 CEST 2017

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