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AUP1 (ancient ubiquitous protein 1)

Identity

Other alias-
HGNC (Hugo) AUP1
LocusID (NCBI) 550
Atlas_Id 60665
Location 2p13.1  [Link to chromosome band 2p13]
Location_base_pair Starts at 74526648 and ends at 74529897 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		AUP1 (2p13.1) / EEF2 (19p13.3)AUP1 (2p13.1) / PLAT (8p11.21)FOXN3 (14q31.3) / AUP1 (2p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)AUP1   891
Cards
Entrez_Gene (NCBI)AUP1  550  ancient ubiquitous protein 1
Aliases
GeneCards (Weizmann)AUP1
Ensembl hg19 (Hinxton)ENSG00000115307 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115307 [Gene_View]  chr2:74526648-74529897 [Contig_View]  AUP1 [Vega]
ICGC DataPortalENSG00000115307
TCGA cBioPortalAUP1
AceView (NCBI)AUP1
Genatlas (Paris)AUP1
WikiGenes550
SOURCE (Princeton)AUP1
Genetics Home Reference (NIH)AUP1
Genomic and cartography
GoldenPath hg38 (UCSC)AUP1  -     chr2:74526648-74529897 -  2p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AUP1  -     2p13.1   [Description]    (hg19-Feb_2009)
EnsemblAUP1 - 2p13.1 [CytoView hg19]  AUP1 - 2p13.1 [CytoView hg38]
Mapping of homologs : NCBIAUP1 [Mapview hg19]  AUP1 [Mapview hg38]
OMIM602434   
Gene and transcription
Genbank (Entrez)AF100746 AF100753 AF100754 AF165515 AI206563
RefSeq transcript (Entrez)NM_181575
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AUP1
Cluster EST : UnigeneHs.411480 [ NCBI ]
CGAP (NCI)Hs.411480
Alternative Splicing GalleryENSG00000115307
Gene ExpressionAUP1 [ NCBI-GEO ]   AUP1 [ EBI - ARRAY_EXPRESS ]   AUP1 [ SEEK ]   AUP1 [ MEM ]
Gene Expression Viewer (FireBrowse)AUP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)550
GTEX Portal (Tissue expression)AUP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y679   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y679  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y679
Splice isoforms : SwissVarQ9Y679
PhosPhoSitePlusQ9Y679
Domaine pattern : Prosite (Expaxy)CUE (PS51140)   
Domains : Interpro (EBI)CUE   
Domain families : Pfam (Sanger)CUE (PF02845)   
Domain families : Pfam (NCBI)pfam02845   
Domain families : Smart (EMBL)CUE (SM00546)  
Conserved Domain (NCBI)AUP1
DMDM Disease mutations550
Blocks (Seattle)AUP1
PDB (SRS)2EKF   
PDB (PDBSum)2EKF   
PDB (IMB)2EKF   
PDB (RSDB)2EKF   
Structural Biology KnowledgeBase2EKF   
SCOP (Structural Classification of Proteins)2EKF   
CATH (Classification of proteins structures)2EKF   
SuperfamilyQ9Y679
Human Protein AtlasENSG00000115307
Peptide AtlasQ9Y679
HPRD03892
IPIIPI00001891   IPI00215815   IPI00917463   IPI00910371   IPI01016054   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y679
IntAct (EBI)Q9Y679
FunCoupENSG00000115307
BioGRIDAUP1
STRING (EMBL)AUP1
ZODIACAUP1
Ontologies - Pathways
QuickGOQ9Y679
Ontology : AmiGOHrd1p ubiquitin ligase ERAD-L complex  protein binding  membrane  integral component of endoplasmic reticulum membrane  ubiquitin-dependent ERAD pathway  retrograde protein transport, ER to cytosol  ubiquitin binding  regulation of catalytic activity  extracellular exosome  ubiquitin-protein transferase activator activity  
Ontology : EGO-EBIHrd1p ubiquitin ligase ERAD-L complex  protein binding  membrane  integral component of endoplasmic reticulum membrane  ubiquitin-dependent ERAD pathway  retrograde protein transport, ER to cytosol  ubiquitin binding  regulation of catalytic activity  extracellular exosome  ubiquitin-protein transferase activator activity  
NDEx NetworkAUP1
Atlas of Cancer Signalling NetworkAUP1
Wikipedia pathwaysAUP1
Orthology - Evolution
OrthoDB550
GeneTree (enSembl)ENSG00000115307
Phylogenetic Trees/Animal Genes : TreeFamAUP1
HOVERGENQ9Y679
HOGENOMQ9Y679
Homologs : HomoloGeneAUP1
Homology/Alignments : Family Browser (UCSC)AUP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAUP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AUP1
dbVarAUP1
ClinVarAUP1
1000_GenomesAUP1 
Exome Variant ServerAUP1
ExAC (Exome Aggregation Consortium)AUP1 (select the gene name)
Genetic variants : HAPMAP550
Genomic Variants (DGV)AUP1 [DGVbeta]
DECIPHERAUP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAUP1 
Mutations
ICGC Data PortalAUP1 
TCGA Data PortalAUP1 
Broad Tumor PortalAUP1
OASIS PortalAUP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAUP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAUP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AUP1
DgiDB (Drug Gene Interaction Database)AUP1
DoCM (Curated mutations)AUP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AUP1 (select a term)
intoGenAUP1
Cancer3DAUP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602434   
Orphanet
MedgenAUP1
Genetic Testing Registry AUP1
NextProtQ9Y679 [Medical]
TSGene550
GENETestsAUP1
Target ValidationAUP1
Huge Navigator AUP1 [HugePedia]
snp3D : Map Gene to Disease550
BioCentury BCIQAUP1
ClinGenAUP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD550
Chemical/Pharm GKB GenePA25182
Clinical trialAUP1
Miscellaneous
canSAR (ICR)AUP1 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAUP1
EVEXAUP1
GoPubMedAUP1
iHOPAUP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:39:20 CEST 2017
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