Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AURKAIP1 (aurora kinase A interacting protein 1)

Identity

Alias_symbol (synonym)AKIP
AIP
FLJ20608
Other aliasMRP-S38
HGNC (Hugo) AURKAIP1
LocusID (NCBI) 54998
Atlas_Id 46620
Location 1p36.33  [Link to chromosome band 1p36]
Location_base_pair Starts at 1373730 and ends at 1375438 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AURKAIP1 (1p36.33) / KAT6B (10q22.2)AURKAIP1 (1p36.33) / MALAT1 (11q13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AURKAIP1   24114
Cards
Entrez_Gene (NCBI)AURKAIP1  54998  aurora kinase A interacting protein 1
AliasesAIP; AKIP; MRP-S38
GeneCards (Weizmann)AURKAIP1
Ensembl hg19 (Hinxton)ENSG00000175756 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175756 [Gene_View]  ENSG00000175756 [Sequence]  chr1:1373730-1375438 [Contig_View]  AURKAIP1 [Vega]
ICGC DataPortalENSG00000175756
TCGA cBioPortalAURKAIP1
AceView (NCBI)AURKAIP1
Genatlas (Paris)AURKAIP1
WikiGenes54998
SOURCE (Princeton)AURKAIP1
Genetics Home Reference (NIH)AURKAIP1
Genomic and cartography
GoldenPath hg38 (UCSC)AURKAIP1  -     chr1:1373730-1375438 -  1p36.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AURKAIP1  -     1p36.33   [Description]    (hg19-Feb_2009)
EnsemblAURKAIP1 - 1p36.33 [CytoView hg19]  AURKAIP1 - 1p36.33 [CytoView hg38]
Mapping of homologs : NCBIAURKAIP1 [Mapview hg19]  AURKAIP1 [Mapview hg38]
OMIM609183   
Gene and transcription
Genbank (Entrez)AJ573456 AK000615 AW576100 BC022808 BC035595
RefSeq transcript (Entrez)NM_001127229 NM_001127230 NM_017900
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AURKAIP1
Cluster EST : UnigeneHs.632515 [ NCBI ]
CGAP (NCI)Hs.632515
Alternative Splicing GalleryENSG00000175756
Gene ExpressionAURKAIP1 [ NCBI-GEO ]   AURKAIP1 [ EBI - ARRAY_EXPRESS ]   AURKAIP1 [ SEEK ]   AURKAIP1 [ MEM ]
Gene Expression Viewer (FireBrowse)AURKAIP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54998
GTEX Portal (Tissue expression)AURKAIP1
Human Protein AtlasENSG00000175756-AURKAIP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWT8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWT8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWT8
Splice isoforms : SwissVarQ9NWT8
PhosPhoSitePlusQ9NWT8
Domains : Interpro (EBI)DUF1713   
Domain families : Pfam (Sanger)DUF1713 (PF08213)   
Domain families : Pfam (NCBI)pfam08213   
Domain families : Smart (EMBL)DUF1713 (SM01155)  
Conserved Domain (NCBI)AURKAIP1
DMDM Disease mutations54998
Blocks (Seattle)AURKAIP1
PDB (SRS)3J9M   
PDB (PDBSum)3J9M   
PDB (IMB)3J9M   
PDB (RSDB)3J9M   
Structural Biology KnowledgeBase3J9M   
SCOP (Structural Classification of Proteins)3J9M   
CATH (Classification of proteins structures)3J9M   
SuperfamilyQ9NWT8
Human Protein Atlas [tissue]ENSG00000175756-AURKAIP1 [tissue]
Peptide AtlasQ9NWT8
HPRD16457
IPIIPI00396260   IPI00739807   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWT8
IntAct (EBI)Q9NWT8
FunCoupENSG00000175756
BioGRIDAURKAIP1
STRING (EMBL)AURKAIP1
ZODIACAURKAIP1
Ontologies - Pathways
QuickGOQ9NWT8
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  mitochondrion  mitochondrial inner membrane  ribosome  mRNA processing  intracellular membrane-bounded organelle  negative regulation of mitotic nuclear division  positive regulation of proteolysis  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  mitochondrion  mitochondrial inner membrane  ribosome  mRNA processing  intracellular membrane-bounded organelle  negative regulation of mitotic nuclear division  positive regulation of proteolysis  mitochondrial translational elongation  mitochondrial translational termination  
NDEx NetworkAURKAIP1
Atlas of Cancer Signalling NetworkAURKAIP1
Wikipedia pathwaysAURKAIP1
Orthology - Evolution
OrthoDB54998
GeneTree (enSembl)ENSG00000175756
Phylogenetic Trees/Animal Genes : TreeFamAURKAIP1
HOVERGENQ9NWT8
HOGENOMQ9NWT8
Homologs : HomoloGeneAURKAIP1
Homology/Alignments : Family Browser (UCSC)AURKAIP1
Gene fusions - Rearrangements
Fusion : QuiverAURKAIP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAURKAIP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AURKAIP1
dbVarAURKAIP1
ClinVarAURKAIP1
1000_GenomesAURKAIP1 
Exome Variant ServerAURKAIP1
ExAC (Exome Aggregation Consortium)ENSG00000175756
GNOMAD BrowserENSG00000175756
Genetic variants : HAPMAP54998
Genomic Variants (DGV)AURKAIP1 [DGVbeta]
DECIPHERAURKAIP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAURKAIP1 
Mutations
ICGC Data PortalAURKAIP1 
TCGA Data PortalAURKAIP1 
Broad Tumor PortalAURKAIP1
OASIS PortalAURKAIP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAURKAIP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAURKAIP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch AURKAIP1
DgiDB (Drug Gene Interaction Database)AURKAIP1
DoCM (Curated mutations)AURKAIP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AURKAIP1 (select a term)
intoGenAURKAIP1
Cancer3DAURKAIP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609183   
Orphanet
DisGeNETAURKAIP1
MedgenAURKAIP1
Genetic Testing Registry AURKAIP1
NextProtQ9NWT8 [Medical]
TSGene54998
GENETestsAURKAIP1
Target ValidationAURKAIP1
Huge Navigator AURKAIP1 [HugePedia]
snp3D : Map Gene to Disease54998
BioCentury BCIQAURKAIP1
ClinGenAURKAIP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54998
Chemical/Pharm GKB GenePA142672568
Clinical trialAURKAIP1
Miscellaneous
canSAR (ICR)AURKAIP1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAURKAIP1
EVEXAURKAIP1
GoPubMedAURKAIP1
iHOPAURKAIP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:15:41 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.