AVP (arginine vasopressin)

2007-02-01  

Identity

HGNC
LOCATION
20p13
LOCUSID
ALIAS
ADH,ARVP,AVP-NPII,AVRP,VP

Other Information

Locus ID:

NCBI: 551
MIM: 192340
HGNC: 894
Ensembl: ENSG00000101200

Variants:

dbSNP: 551
ClinVar: 551
TCGA: ENSG00000101200
COSMIC: AVP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101200ENST00000380293P01185
ENSG00000101200ENST00000380293X5DQP6

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
Vasopressin-regulated water reabsorptionKEGGko04962
Vasopressin-regulated water reabsorptionKEGGhsa04962
DiseaseREACTOMER-HSA-1643685
Disorders of transmembrane transportersREACTOMER-HSA-5619115
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
Vasopressin-like receptorsREACTOMER-HSA-388479
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907
Circadian ClockREACTOMER-HSA-400253
BMAL1:CLOCK,NPAS2 activates circadian gene expressionREACTOMER-HSA-1368108
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of vitamins, nucleosides, and related moleculesREACTOMER-HSA-425397
Transport of organic anionsREACTOMER-HSA-879518
Aquaporin-mediated transportREACTOMER-HSA-445717
Vasopressin regulates renal water homeostasis via AquaporinsREACTOMER-HSA-432040
SLC transporter disordersREACTOMER-HSA-5619102
Defective AVP causes neurohypophyseal diabetes insipidus (NDI)REACTOMER-HSA-5619099
Phospholipase D signaling pathwayKEGGko04072
Phospholipase D signaling pathwayKEGGhsa04072
Clathrin-mediated endocytosisREACTOMER-HSA-8856828
Cargo recognition for clathrin-mediated endocytosisREACTOMER-HSA-8856825

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
222453142012The contributions of oxytocin and vasopressin pathway genes to human behavior.83
204397852010Plasma copeptin and the risk of diabetes mellitus.60
201445092010Marital behavior, oxytocin, vasopressin, and wound healing.49
198471552010Copeptin, a surrogate marker of vasopressin, is associated with microalbuminuria in a large population cohort.36
190860532009Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.34
193668522009Plasma carboxy-terminal provasopressin (copeptin): a novel marker of insulin resistance and metabolic syndrome.34
214900732011Plasma copeptin, a unifying factor behind the metabolic syndrome.33
183840792008Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder.30
203685122010Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response.30
204680642010Association study of 182 candidate genes in anorexia nervosa.30

Citation

Dessen P

AVP (arginine vasopressin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46535/avp