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AVPR1A (arginine vasopressin receptor 1A)

Identity

Alias_namesAVPR1
Other aliasAVPR V1a
V1aR
HGNC (Hugo) AVPR1A
LocusID (NCBI) 552
Atlas_Id 53983
Location 12q14.2  [Link to chromosome band 12q14]
Location_base_pair Starts at 63536539 and ends at 63546590 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AVPR1A   895
Cards
Entrez_Gene (NCBI)AVPR1A  552  arginine vasopressin receptor 1A
AliasesAVPR; AVPR1; V1aR
GeneCards (Weizmann)AVPR1A
Ensembl hg19 (Hinxton)ENSG00000166148 [Gene_View]  chr12:63536539-63546590 [Contig_View]  AVPR1A [Vega]
Ensembl hg38 (Hinxton)ENSG00000166148 [Gene_View]  chr12:63536539-63546590 [Contig_View]  AVPR1A [Vega]
ICGC DataPortalENSG00000166148
TCGA cBioPortalAVPR1A
AceView (NCBI)AVPR1A
Genatlas (Paris)AVPR1A
WikiGenes552
SOURCE (Princeton)AVPR1A
Genetics Home Reference (NIH)AVPR1A
Genomic and cartography
GoldenPath hg19 (UCSC)AVPR1A  -     chr12:63536539-63546590 -  12q14.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AVPR1A  -     12q14.2   [Description]    (hg38-Dec_2013)
EnsemblAVPR1A - 12q14.2 [CytoView hg19]  AVPR1A - 12q14.2 [CytoView hg38]
Mapping of homologs : NCBIAVPR1A [Mapview hg19]  AVPR1A [Mapview hg38]
OMIM600821   
Gene and transcription
Genbank (Entrez)AA533159 AF030625 AF101725 AY322550 BC074803
RefSeq transcript (Entrez)NM_000706
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)AVPR1A
Cluster EST : UnigeneHs.2131 [ NCBI ]
CGAP (NCI)Hs.2131
Alternative Splicing GalleryENSG00000166148
Gene ExpressionAVPR1A [ NCBI-GEO ]   AVPR1A [ EBI - ARRAY_EXPRESS ]   AVPR1A [ SEEK ]   AVPR1A [ MEM ]
Gene Expression Viewer (FireBrowse)AVPR1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)552
GTEX Portal (Tissue expression)AVPR1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP37288   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP37288  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP37288
Splice isoforms : SwissVarP37288
PhosPhoSitePlusP37288
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)DUF1856    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Vasoprsn_rcpt    Vprs_V1A_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)    DUF1856 (PF08983)   
Domain families : Pfam (NCBI)pfam00001    pfam08983   
Conserved Domain (NCBI)AVPR1A
DMDM Disease mutations552
Blocks (Seattle)AVPR1A
PDB (SRS)1YTV   
PDB (PDBSum)1YTV   
PDB (IMB)1YTV   
PDB (RSDB)1YTV   
Structural Biology KnowledgeBase1YTV   
SCOP (Structural Classification of Proteins)1YTV   
CATH (Classification of proteins structures)1YTV   
SuperfamilyP37288
Human Protein AtlasENSG00000166148
Peptide AtlasP37288
HPRD02894
IPIIPI01020865   IPI00020968   
Protein Interaction databases
DIP (DOE-UCLA)P37288
IntAct (EBI)P37288
FunCoupENSG00000166148
BioGRIDAVPR1A
STRING (EMBL)AVPR1A
ZODIACAVPR1A
Ontologies - Pathways
QuickGOP37288
Ontology : AmiGOregulation of systemic arterial blood pressure by vasopressin  maternal aggressive behavior  positive regulation of systemic arterial blood pressure  vasopressin receptor activity  protein kinase C binding  protein binding  endosome  cytosol  plasma membrane  integral component of plasma membrane  generation of precursor metabolites and energy  G-protein coupled receptor signaling pathway  activation of phospholipase C activity  positive regulation of cytosolic calcium ion concentration  negative regulation of female receptivity  grooming behavior  blood circulation  positive regulation of cell proliferation  positive regulation of heart rate  positive regulation of glutamate secretion  myotube differentiation  peptide hormone binding  calcium-mediated signaling  telencephalon development  positive regulation of cell growth  positive regulation of prostaglandin biosynthetic process  cytoplasmic vesicle  V1A vasopressin receptor binding  positive regulation of cellular pH reduction  cellular response to hormone stimulus  social behavior  positive regulation of renal sodium excretion  peptide binding  cellular response to water deprivation  maternal behavior  sperm ejaculation  penile erection  positive regulation of vasoconstriction  response to corticosterone  negative regulation of transmission of nerve impulse  response to peptide  
Ontology : EGO-EBIregulation of systemic arterial blood pressure by vasopressin  maternal aggressive behavior  positive regulation of systemic arterial blood pressure  vasopressin receptor activity  protein kinase C binding  protein binding  endosome  cytosol  plasma membrane  integral component of plasma membrane  generation of precursor metabolites and energy  G-protein coupled receptor signaling pathway  activation of phospholipase C activity  positive regulation of cytosolic calcium ion concentration  negative regulation of female receptivity  grooming behavior  blood circulation  positive regulation of cell proliferation  positive regulation of heart rate  positive regulation of glutamate secretion  myotube differentiation  peptide hormone binding  calcium-mediated signaling  telencephalon development  positive regulation of cell growth  positive regulation of prostaglandin biosynthetic process  cytoplasmic vesicle  V1A vasopressin receptor binding  positive regulation of cellular pH reduction  cellular response to hormone stimulus  social behavior  positive regulation of renal sodium excretion  peptide binding  cellular response to water deprivation  maternal behavior  sperm ejaculation  penile erection  positive regulation of vasoconstriction  response to corticosterone  negative regulation of transmission of nerve impulse  response to peptide  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction    Vascular smooth muscle contraction   
NDEx NetworkAVPR1A
Atlas of Cancer Signalling NetworkAVPR1A
Wikipedia pathwaysAVPR1A
Orthology - Evolution
OrthoDB552
GeneTree (enSembl)ENSG00000166148
Phylogenetic Trees/Animal Genes : TreeFamAVPR1A
HOVERGENP37288
HOGENOMP37288
Homologs : HomoloGeneAVPR1A
Homology/Alignments : Family Browser (UCSC)AVPR1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAVPR1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AVPR1A
dbVarAVPR1A
ClinVarAVPR1A
1000_GenomesAVPR1A 
Exome Variant ServerAVPR1A
ExAC (Exome Aggregation Consortium)AVPR1A (select the gene name)
Genetic variants : HAPMAP552
Genomic Variants (DGV)AVPR1A [DGVbeta]
DECIPHER (Syndromes)12:63536539-63546590  ENSG00000166148
CONAN: Copy Number AnalysisAVPR1A 
Mutations
ICGC Data PortalAVPR1A 
TCGA Data PortalAVPR1A 
Broad Tumor PortalAVPR1A
OASIS PortalAVPR1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAVPR1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAVPR1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AVPR1A
DgiDB (Drug Gene Interaction Database)AVPR1A
DoCM (Curated mutations)AVPR1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AVPR1A (select a term)
intoGenAVPR1A
Cancer3DAVPR1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600821   
Orphanet
MedgenAVPR1A
Genetic Testing Registry AVPR1A
NextProtP37288 [Medical]
TSGene552
GENETestsAVPR1A
Huge Navigator AVPR1A [HugePedia]
snp3D : Map Gene to Disease552
BioCentury BCIQAVPR1A
ClinGenAVPR1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD552
Chemical/Pharm GKB GenePA25187
Clinical trialAVPR1A
Miscellaneous
canSAR (ICR)AVPR1A (select the gene name)
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAVPR1A
EVEXAVPR1A
GoPubMedAVPR1A
iHOPAVPR1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:53:35 CEST 2017

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