Atlas of Genetics and Cytogenetics in Oncology and Haematology


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AZIN1 (antizyme inhibitor 1)

Identity

Alias (NCBI)AZI
AZI1
AZIA1
OAZI
OAZIN
ODC1L
HGNC (Hugo) AZIN1
HGNC Alias symbOAZI
ODC1L
HGNC Alias nameornithine decarboxylase 1-like
HGNC Previous nameOAZIN
HGNC Previous nameornithine decarboxylase antizyme inhibitor
LocusID (NCBI) 51582
Atlas_Id 51832
Location 8q22.3  [Link to chromosome band 8q22]
Location_base_pair Starts at 102826308 and ends at 102864163 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AZIN1 (8q22.3) / AEBP2 (12p12.3)AZIN1 (8q22.3) / ATP6V1C1 (8q22.3)AZIN1 (8q22.3) / RNF19A (8q22.2)
AZIN1 (8q22.3) / TRIM46 (1q22)COL6A1 (21q22.3) / AZIN1 (8q22.3)LONP1 (19p13.3) / AZIN1 (8q22.3)
TASP1 (20p12.1) / AZIN1 (8q22.3)YWHAZ (8q22.3) / AZIN1 (8q22.3)AZIN1 8q22.3 / ATP6V1C1 8q22.3
AZIN1 8q22.3 / RNF19A 8q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)AZIN1   16432
Cards
Entrez_Gene (NCBI)AZIN1    antizyme inhibitor 1
AliasesAZI; AZI1; AZIA1; OAZI; 
OAZIN; ODC1L
GeneCards (Weizmann)AZIN1
Ensembl hg19 (Hinxton)ENSG00000155096 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155096 [Gene_View]  ENSG00000155096 [Sequence]  chr8:102826308-102864163 [Contig_View]  AZIN1 [Vega]
ICGC DataPortalENSG00000155096
TCGA cBioPortalAZIN1
AceView (NCBI)AZIN1
Genatlas (Paris)AZIN1
SOURCE (Princeton)AZIN1
Genetics Home Reference (NIH)AZIN1
Genomic and cartography
GoldenPath hg38 (UCSC)AZIN1  -     chr8:102826308-102864163 -  8q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AZIN1  -     8q22.3   [Description]    (hg19-Feb_2009)
GoldenPathAZIN1 - 8q22.3 [CytoView hg19]  AZIN1 - 8q22.3 [CytoView hg38]
ImmunoBaseENSG00000155096
Genome Data Viewer NCBIAZIN1 [Mapview hg19]  
OMIM607909   
Gene and transcription
Genbank (Entrez)AF070634 AI671875 AK095493 AK290516 AU280209
RefSeq transcript (Entrez)NM_001301668 NM_001363010 NM_001363011 NM_001363012 NM_001363013 NM_001363014 NM_001363024 NM_001363083 NM_015878 NM_148174
Consensus coding sequences : CCDS (NCBI)AZIN1
Gene ExpressionAZIN1 [ NCBI-GEO ]   AZIN1 [ EBI - ARRAY_EXPRESS ]   AZIN1 [ SEEK ]   AZIN1 [ MEM ]
Gene Expression Viewer (FireBrowse)AZIN1 [ Firebrowse - Broad ]
GenevisibleExpression of AZIN1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51582
GTEX Portal (Tissue expression)AZIN1
Human Protein AtlasENSG00000155096-AZIN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14977   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14977  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14977
PhosPhoSitePlusO14977
Domaine pattern : Prosite (Expaxy)ODR_DC_2_2 (PS00879)   
Domains : Interpro (EBI)Ala_racemase/Decarboxylase_C    Azin1    De-COase2_C    De-COase2_CS    De-COase2_N    Orn/DAP/Arg_de-COase    Orn_de-COase    PLP-binding_barrel   
Domain families : Pfam (Sanger)Orn_Arg_deC_N (PF02784)    Orn_DAP_Arg_deC (PF00278)   
Domain families : Pfam (NCBI)pfam02784    pfam00278   
Conserved Domain (NCBI)AZIN1
PDB (RSDB)4ZGZ   
PDB Europe4ZGZ   
PDB (PDBSum)4ZGZ   
PDB (IMB)4ZGZ   
Structural Biology KnowledgeBase4ZGZ   
SCOP (Structural Classification of Proteins)4ZGZ   
CATH (Classification of proteins structures)4ZGZ   
SuperfamilyO14977
AlphaFold pdb e-kbO14977   
Human Protein Atlas [tissue]ENSG00000155096-AZIN1 [tissue]
HPRD07443
Protein Interaction databases
DIP (DOE-UCLA)O14977
IntAct (EBI)O14977
BioGRIDAZIN1
STRING (EMBL)AZIN1
ZODIACAZIN1
Ontologies - Pathways
QuickGOO14977
Ontology : AmiGOornithine decarboxylase activity  protein binding  nucleus  cytoplasm  cytosol  regulation of cellular amino acid metabolic process  putrescine biosynthetic process from ornithine  negative regulation of protein catabolic process  negative regulation of protein catabolic process  ornithine decarboxylase activator activity  ornithine decarboxylase activator activity  regulation of catalytic activity  positive regulation of polyamine transmembrane transport  positive regulation of polyamine transmembrane transport  
Ontology : EGO-EBIornithine decarboxylase activity  protein binding  nucleus  cytoplasm  cytosol  regulation of cellular amino acid metabolic process  putrescine biosynthetic process from ornithine  negative regulation of protein catabolic process  negative regulation of protein catabolic process  ornithine decarboxylase activator activity  ornithine decarboxylase activator activity  regulation of catalytic activity  positive regulation of polyamine transmembrane transport  positive regulation of polyamine transmembrane transport  
NDEx NetworkAZIN1
Atlas of Cancer Signalling NetworkAZIN1
Wikipedia pathwaysAZIN1
Orthology - Evolution
OrthoDB51582
GeneTree (enSembl)ENSG00000155096
Phylogenetic Trees/Animal Genes : TreeFamAZIN1
Homologs : HomoloGeneAZIN1
Homology/Alignments : Family Browser (UCSC)AZIN1
Gene fusions - Rearrangements
Fusion : MitelmanAZIN1/ATP6V1C1 [8q22.3/8q22.3]  
Fusion : MitelmanAZIN1/RNF19A [8q22.3/8q22.2]  
Fusion : QuiverAZIN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAZIN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AZIN1
dbVarAZIN1
ClinVarAZIN1
MonarchAZIN1
1000_GenomesAZIN1 
Exome Variant ServerAZIN1
GNOMAD BrowserENSG00000155096
Varsome BrowserAZIN1
ACMGAZIN1 variants
VarityO14977
Genomic Variants (DGV)AZIN1 [DGVbeta]
DECIPHERAZIN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAZIN1 
Mutations
ICGC Data PortalAZIN1 
TCGA Data PortalAZIN1 
Broad Tumor PortalAZIN1
OASIS PortalAZIN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAZIN1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DAZIN1
Mutations and Diseases : HGMDAZIN1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaAZIN1
DgiDB (Drug Gene Interaction Database)AZIN1
DoCM (Curated mutations)AZIN1
CIViC (Clinical Interpretations of Variants in Cancer)AZIN1
Cancer3DAZIN1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607909   
Orphanet
DisGeNETAZIN1
MedgenAZIN1
Genetic Testing Registry AZIN1
NextProtO14977 [Medical]
GENETestsAZIN1
Target ValidationAZIN1
Huge Navigator AZIN1 [HugePedia]
ClinGenAZIN1
Clinical trials, drugs, therapy
MyCancerGenomeAZIN1
Protein Interactions : CTDAZIN1
Pharm GKB GenePA31887
PharosO14977
Clinical trialAZIN1
Miscellaneous
canSAR (ICR)AZIN1
HarmonizomeAZIN1
DataMed IndexAZIN1
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXAZIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:00:46 CEST 2021

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