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AZIN1 (antizyme inhibitor 1)

Identity

Alias_namesOAZIN
ornithine decarboxylase antizyme inhibitor
Alias_symbol (synonym)OAZI
ODC1L
Other aliasAZI
AZI1
AZIA1
HGNC (Hugo) AZIN1
LocusID (NCBI) 51582
Atlas_Id 51832
Location 8q22.3  [Link to chromosome band 8q22]
Location_base_pair Starts at 102826302 and ends at 102864200 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AZIN1 (8q22.3) / AEBP2 (12p12.3)AZIN1 (8q22.3) / ATP6V1C1 (8q22.3)AZIN1 (8q22.3) / RNF19A (8q22.2)
AZIN1 (8q22.3) / TRIM46 (1q22)COL6A1 (21q22.3) / AZIN1 (8q22.3)LONP1 (19p13.3) / AZIN1 (8q22.3)
TASP1 (20p12.1) / AZIN1 (8q22.3)YWHAZ (8q22.3) / AZIN1 (8q22.3)AZIN1 8q22.3 / ATP6V1C1 8q22.3
AZIN1 8q22.3 / RNF19A 8q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AZIN1   16432
Cards
Entrez_Gene (NCBI)AZIN1  51582  antizyme inhibitor 1
AliasesAZI; AZI1; AZIA1; OAZI; 
OAZIN; ODC1L
GeneCards (Weizmann)AZIN1
Ensembl hg19 (Hinxton)ENSG00000155096 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155096 [Gene_View]  chr8:102826302-102864200 [Contig_View]  AZIN1 [Vega]
ICGC DataPortalENSG00000155096
TCGA cBioPortalAZIN1
AceView (NCBI)AZIN1
Genatlas (Paris)AZIN1
WikiGenes51582
SOURCE (Princeton)AZIN1
Genetics Home Reference (NIH)AZIN1
Genomic and cartography
GoldenPath hg38 (UCSC)AZIN1  -     chr8:102826302-102864200 -  8q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AZIN1  -     8q22.3   [Description]    (hg19-Feb_2009)
EnsemblAZIN1 - 8q22.3 [CytoView hg19]  AZIN1 - 8q22.3 [CytoView hg38]
Mapping of homologs : NCBIAZIN1 [Mapview hg19]  AZIN1 [Mapview hg38]
OMIM607909   
Gene and transcription
Genbank (Entrez)AF070634 AI671875 AK095493 AK290516 AU280209
RefSeq transcript (Entrez)NM_001301668 NM_015878 NM_148174
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AZIN1
Cluster EST : UnigeneHs.459106 [ NCBI ]
CGAP (NCI)Hs.459106
Alternative Splicing GalleryENSG00000155096
Gene ExpressionAZIN1 [ NCBI-GEO ]   AZIN1 [ EBI - ARRAY_EXPRESS ]   AZIN1 [ SEEK ]   AZIN1 [ MEM ]
Gene Expression Viewer (FireBrowse)AZIN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51582
GTEX Portal (Tissue expression)AZIN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14977   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14977  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14977
Splice isoforms : SwissVarO14977
PhosPhoSitePlusO14977
Domaine pattern : Prosite (Expaxy)ODR_DC_2_2 (PS00879)   
Domains : Interpro (EBI)Ala_racemase/Decarboxylase_C    Azin1    De-COase2_C    De-COase2_CS    De-COase2_N    Orn/DAP/Arg_de-COase    Orn_de-COase    PLP-binding_barrel   
Domain families : Pfam (Sanger)Orn_Arg_deC_N (PF02784)    Orn_DAP_Arg_deC (PF00278)   
Domain families : Pfam (NCBI)pfam02784    pfam00278   
Conserved Domain (NCBI)AZIN1
DMDM Disease mutations51582
Blocks (Seattle)AZIN1
PDB (SRS)4ZGZ   
PDB (PDBSum)4ZGZ   
PDB (IMB)4ZGZ   
PDB (RSDB)4ZGZ   
Structural Biology KnowledgeBase4ZGZ   
SCOP (Structural Classification of Proteins)4ZGZ   
CATH (Classification of proteins structures)4ZGZ   
SuperfamilyO14977
Human Protein AtlasENSG00000155096
Peptide AtlasO14977
HPRD07443
IPIIPI00749254   IPI00975796   IPI00985412   
Protein Interaction databases
DIP (DOE-UCLA)O14977
IntAct (EBI)O14977
FunCoupENSG00000155096
BioGRIDAZIN1
STRING (EMBL)AZIN1
ZODIACAZIN1
Ontologies - Pathways
QuickGOO14977
Ontology : AmiGOcatalytic activity  protein binding  nucleus  cytoplasm  cytosol  regulation of cellular amino acid metabolic process  putrescine biosynthetic process from ornithine  negative regulation of protein catabolic process  ornithine decarboxylase activator activity  positive regulation of catalytic activity  positive regulation of polyamine transmembrane transport  
Ontology : EGO-EBIcatalytic activity  protein binding  nucleus  cytoplasm  cytosol  regulation of cellular amino acid metabolic process  putrescine biosynthetic process from ornithine  negative regulation of protein catabolic process  ornithine decarboxylase activator activity  positive regulation of catalytic activity  positive regulation of polyamine transmembrane transport  
NDEx NetworkAZIN1
Atlas of Cancer Signalling NetworkAZIN1
Wikipedia pathwaysAZIN1
Orthology - Evolution
OrthoDB51582
GeneTree (enSembl)ENSG00000155096
Phylogenetic Trees/Animal Genes : TreeFamAZIN1
HOVERGENO14977
HOGENOMO14977
Homologs : HomoloGeneAZIN1
Homology/Alignments : Family Browser (UCSC)AZIN1
Gene fusions - Rearrangements
Fusion : MitelmanAZIN1/ATP6V1C1 [8q22.3/8q22.3]  
Fusion : MitelmanAZIN1/RNF19A [8q22.3/8q22.2]  [t(8;8)(q22;q22)]  
Fusion: TCGAAZIN1 8q22.3 ATP6V1C1 8q22.3 SKCM
Fusion: TCGAAZIN1 8q22.3 RNF19A 8q22.2 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAZIN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AZIN1
dbVarAZIN1
ClinVarAZIN1
1000_GenomesAZIN1 
Exome Variant ServerAZIN1
ExAC (Exome Aggregation Consortium)AZIN1 (select the gene name)
Genetic variants : HAPMAP51582
Genomic Variants (DGV)AZIN1 [DGVbeta]
DECIPHERAZIN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAZIN1 
Mutations
ICGC Data PortalAZIN1 
TCGA Data PortalAZIN1 
Broad Tumor PortalAZIN1
OASIS PortalAZIN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAZIN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAZIN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AZIN1
DgiDB (Drug Gene Interaction Database)AZIN1
DoCM (Curated mutations)AZIN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AZIN1 (select a term)
intoGenAZIN1
Cancer3DAZIN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607909   
Orphanet
MedgenAZIN1
Genetic Testing Registry AZIN1
NextProtO14977 [Medical]
TSGene51582
GENETestsAZIN1
Target ValidationAZIN1
Huge Navigator AZIN1 [HugePedia]
snp3D : Map Gene to Disease51582
BioCentury BCIQAZIN1
ClinGenAZIN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51582
Chemical/Pharm GKB GenePA31887
Clinical trialAZIN1
Miscellaneous
canSAR (ICR)AZIN1 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAZIN1
EVEXAZIN1
GoPubMedAZIN1
iHOPAZIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 18:58:47 CEST 2017

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