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AZIN2 (antizyme inhibitor 2)

Identity

Alias_namesADC
arginine decarboxylase
Alias_symbol (synonym)ODC-p
ODC1L
KIAA1945
ODCp
Other aliasAZI2
AZIB1
HGNC (Hugo) AZIN2
LocusID (NCBI) 113451
Atlas_Id 53943
Location 1p35.1  [Link to chromosome band 1p35]
Location_base_pair Starts at 33546714 and ends at 33586132 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AZIN2 (1p35.1) / PHIP (6q14.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AZIN2   29957
Cards
Entrez_Gene (NCBI)AZIN2  113451  antizyme inhibitor 2
AliasesADC; AZI2; AZIB1; ODC-p; 
ODC1L; ODCp
GeneCards (Weizmann)AZIN2
Ensembl hg19 (Hinxton)ENSG00000142920 [Gene_View]  chr1:33546714-33586132 [Contig_View]  AZIN2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000142920 [Gene_View]  chr1:33546714-33586132 [Contig_View]  AZIN2 [Vega]
ICGC DataPortalENSG00000142920
TCGA cBioPortalAZIN2
AceView (NCBI)AZIN2
Genatlas (Paris)AZIN2
WikiGenes113451
SOURCE (Princeton)AZIN2
Genetics Home Reference (NIH)AZIN2
Genomic and cartography
GoldenPath hg19 (UCSC)AZIN2  -     chr1:33546714-33586132 +  1p35.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AZIN2  -     1p35.1   [Description]    (hg38-Dec_2013)
EnsemblAZIN2 - 1p35.1 [CytoView hg19]  AZIN2 - 1p35.1 [CytoView hg38]
Mapping of homologs : NCBIAZIN2 [Mapview hg19]  AZIN2 [Mapview hg38]
OMIM608353   
Gene and transcription
Genbank (Entrez)AB075825 AK057051 AK095127 AK122697 AK315677
RefSeq transcript (Entrez)NM_001293562 NM_001301823 NM_001301824 NM_001301825 NM_001301826 NM_052998
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)AZIN2
Cluster EST : UnigeneHs.101807 [ NCBI ]
CGAP (NCI)Hs.101807
Alternative Splicing GalleryENSG00000142920
Gene ExpressionAZIN2 [ NCBI-GEO ]   AZIN2 [ EBI - ARRAY_EXPRESS ]   AZIN2 [ SEEK ]   AZIN2 [ MEM ]
Gene Expression Viewer (FireBrowse)AZIN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)113451
GTEX Portal (Tissue expression)AZIN2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96A70   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96A70  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96A70
Splice isoforms : SwissVarQ96A70
PhosPhoSitePlusQ96A70
Domaine pattern : Prosite (Expaxy)ODR_DC_2_1 (PS00878)    ODR_DC_2_2 (PS00879)   
Domains : Interpro (EBI)Ala_racemase/Decarboxylase_C    Azin2    De-COase2_C    De-COase2_CS    De-COase2_N    De-COase2_pyr-phos_BS    Orn/DAP/Arg_de-COase    Orn_de-COase    PLP-binding_barrel   
Domain families : Pfam (Sanger)Orn_Arg_deC_N (PF02784)    Orn_DAP_Arg_deC (PF00278)   
Domain families : Pfam (NCBI)pfam02784    pfam00278   
Conserved Domain (NCBI)AZIN2
DMDM Disease mutations113451
Blocks (Seattle)AZIN2
SuperfamilyQ96A70
Human Protein AtlasENSG00000142920
Peptide AtlasQ96A70
HPRD17657
IPIIPI00165042   IPI00218757   IPI00218758   IPI00411394   IPI00218760   
Protein Interaction databases
DIP (DOE-UCLA)Q96A70
IntAct (EBI)Q96A70
FunCoupENSG00000142920
BioGRIDAZIN2
STRING (EMBL)AZIN2
ZODIACAZIN2
Ontologies - Pathways
QuickGOQ96A70
Ontology : AmiGOprotein binding  nucleus  mitochondrion  cis-Golgi network  trans-Golgi network  cytosol  spermatogenesis  arginine decarboxylase activity  putrescine transmembrane transporter activity  putrescine transport  transport vesicle  axon  dendrite  cytoplasmic vesicle  endoplasmic reticulum-Golgi intermediate compartment membrane  putrescine biosynthetic process from ornithine  negative regulation of protein catabolic process  negative regulation of protein catabolic process  ornithine decarboxylase activator activity  ornithine decarboxylase activator activity  positive regulation of catalytic activity  perikaryon  perinuclear region of cytoplasm  agmatine biosynthetic process  trans-Golgi network membrane organization  positive regulation of polyamine transmembrane transport  granular vesicle  
Ontology : EGO-EBIprotein binding  nucleus  mitochondrion  cis-Golgi network  trans-Golgi network  cytosol  spermatogenesis  arginine decarboxylase activity  putrescine transmembrane transporter activity  putrescine transport  transport vesicle  axon  dendrite  cytoplasmic vesicle  endoplasmic reticulum-Golgi intermediate compartment membrane  putrescine biosynthetic process from ornithine  negative regulation of protein catabolic process  negative regulation of protein catabolic process  ornithine decarboxylase activator activity  ornithine decarboxylase activator activity  positive regulation of catalytic activity  perikaryon  perinuclear region of cytoplasm  agmatine biosynthetic process  trans-Golgi network membrane organization  positive regulation of polyamine transmembrane transport  granular vesicle  
NDEx NetworkAZIN2
Atlas of Cancer Signalling NetworkAZIN2
Wikipedia pathwaysAZIN2
Orthology - Evolution
OrthoDB113451
GeneTree (enSembl)ENSG00000142920
Phylogenetic Trees/Animal Genes : TreeFamAZIN2
HOVERGENQ96A70
HOGENOMQ96A70
Homologs : HomoloGeneAZIN2
Homology/Alignments : Family Browser (UCSC)AZIN2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAZIN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AZIN2
dbVarAZIN2
ClinVarAZIN2
1000_GenomesAZIN2 
Exome Variant ServerAZIN2
ExAC (Exome Aggregation Consortium)AZIN2 (select the gene name)
Genetic variants : HAPMAP113451
Genomic Variants (DGV)AZIN2 [DGVbeta]
DECIPHER (Syndromes)1:33546714-33586132  ENSG00000142920
CONAN: Copy Number AnalysisAZIN2 
Mutations
ICGC Data PortalAZIN2 
TCGA Data PortalAZIN2 
Broad Tumor PortalAZIN2
OASIS PortalAZIN2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDAZIN2
BioMutasearch AZIN2
DgiDB (Drug Gene Interaction Database)AZIN2
DoCM (Curated mutations)AZIN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AZIN2 (select a term)
intoGenAZIN2
Cancer3DAZIN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608353   
Orphanet
MedgenAZIN2
Genetic Testing Registry AZIN2
NextProtQ96A70 [Medical]
TSGene113451
GENETestsAZIN2
Huge Navigator AZIN2 [HugePedia]
snp3D : Map Gene to Disease113451
BioCentury BCIQAZIN2
ClinGenAZIN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD113451
Chemical/Pharm GKB GenePA142672642
Clinical trialAZIN2
Miscellaneous
canSAR (ICR)AZIN2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAZIN2
EVEXAZIN2
GoPubMedAZIN2
iHOPAZIN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 12:57:10 CET 2017

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