Atlas of Genetics and Cytogenetics in Oncology and Haematology


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AZU1 (azurocidin 1)

Identity

Alias_symbol (synonym)AZU
CAP37
AZAMP
HBP
NAZC
HUMAZUR
Other aliashHBP
HGNC (Hugo) AZU1
LocusID (NCBI) 566
Atlas_Id 736
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 827826 and ends at 832018 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SF3A2 (19p13.3) / AZU1 (19p13.3)SF3A2 19p13.3 / AZU1 19p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AZU1   913
Cards
Entrez_Gene (NCBI)AZU1  566  azurocidin 1
AliasesAZAMP; AZU; CAP37; HBP; 
HUMAZUR; NAZC; hHBP
GeneCards (Weizmann)AZU1
Ensembl hg19 (Hinxton)ENSG00000172232 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172232 [Gene_View]  chr19:827826-832018 [Contig_View]  AZU1 [Vega]
ICGC DataPortalENSG00000172232
TCGA cBioPortalAZU1
AceView (NCBI)AZU1
Genatlas (Paris)AZU1
WikiGenes566
SOURCE (Princeton)AZU1
Genetics Home Reference (NIH)AZU1
Genomic and cartography
GoldenPath hg38 (UCSC)AZU1  -     chr19:827826-832018 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AZU1  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblAZU1 - 19p13.3 [CytoView hg19]  AZU1 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIAZU1 [Mapview hg19]  AZU1 [Mapview hg38]
OMIM162815   
Gene and transcription
Genbank (Entrez)BC044940 BC069495 BC093931 BC093933 BU617927
RefSeq transcript (Entrez)NM_001700
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_187622
Consensus coding sequences : CCDS (NCBI)AZU1
Cluster EST : UnigeneHs.72885 [ NCBI ]
CGAP (NCI)Hs.72885
Alternative Splicing GalleryENSG00000172232
Gene ExpressionAZU1 [ NCBI-GEO ]   AZU1 [ EBI - ARRAY_EXPRESS ]   AZU1 [ SEEK ]   AZU1 [ MEM ]
Gene Expression Viewer (FireBrowse)AZU1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)566
GTEX Portal (Tissue expression)AZU1
Human Protein AtlasENSG00000172232-AZU1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20160   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20160  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20160
Splice isoforms : SwissVarP20160
PhosPhoSitePlusP20160
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)AZU1
DMDM Disease mutations566
Blocks (Seattle)AZU1
PDB (SRS)1A7S    1AE5    1FY1    1FY3   
PDB (PDBSum)1A7S    1AE5    1FY1    1FY3   
PDB (IMB)1A7S    1AE5    1FY1    1FY3   
PDB (RSDB)1A7S    1AE5    1FY1    1FY3   
Structural Biology KnowledgeBase1A7S    1AE5    1FY1    1FY3   
SCOP (Structural Classification of Proteins)1A7S    1AE5    1FY1    1FY3   
CATH (Classification of proteins structures)1A7S    1AE5    1FY1    1FY3   
SuperfamilyP20160
Human Protein Atlas [tissue]ENSG00000172232-AZU1 [tissue]
Peptide AtlasP20160
HPRD01221
IPIIPI00022246   IPI00383981   
Protein Interaction databases
DIP (DOE-UCLA)P20160
IntAct (EBI)P20160
FunCoupENSG00000172232
BioGRIDAZU1
STRING (EMBL)AZU1
ZODIACAZU1
Ontologies - Pathways
QuickGOP20160
Ontology : AmiGOmicroglial cell activation  serine-type endopeptidase activity  protein binding  extracellular region  extracellular region  extracellular space  proteolysis  inflammatory response  protein kinase C-activating G-protein coupled receptor signaling pathway  heparin binding  peptidase activity  glial cell migration  positive regulation of gene expression  positive regulation of peptidyl-threonine phosphorylation  toxic substance binding  protein processing  antimicrobial humoral response  extrinsic component of membrane  azurophil granule membrane  azurophil granule lumen  calcium-mediated signaling using intracellular calcium source  monocyte activation  positive regulation of tumor necrosis factor biosynthetic process  azurophil granule  negative regulation of apoptotic process  regulation of vascular permeability  neutrophil degranulation  heparan sulfate proteoglycan binding  cellular extravasation  positive regulation of MHC class II biosynthetic process  positive regulation of cell adhesion  positive regulation of protein kinase activity  macrophage chemotaxis  positive regulation of interleukin-1 beta biosynthetic process  positive regulation of fractalkine biosynthetic process  positive regulation of phagocytosis  defense response to Gram-negative bacterium  induction of positive chemotaxis  defense response to virus  cell chemotaxis  extracellular exosome  protein kinase C signaling  neutrophil mediated killing of bacterium  
Ontology : EGO-EBImicroglial cell activation  serine-type endopeptidase activity  protein binding  extracellular region  extracellular region  extracellular space  proteolysis  inflammatory response  protein kinase C-activating G-protein coupled receptor signaling pathway  heparin binding  peptidase activity  glial cell migration  positive regulation of gene expression  positive regulation of peptidyl-threonine phosphorylation  toxic substance binding  protein processing  antimicrobial humoral response  extrinsic component of membrane  azurophil granule membrane  azurophil granule lumen  calcium-mediated signaling using intracellular calcium source  monocyte activation  positive regulation of tumor necrosis factor biosynthetic process  azurophil granule  negative regulation of apoptotic process  regulation of vascular permeability  neutrophil degranulation  heparan sulfate proteoglycan binding  cellular extravasation  positive regulation of MHC class II biosynthetic process  positive regulation of cell adhesion  positive regulation of protein kinase activity  macrophage chemotaxis  positive regulation of interleukin-1 beta biosynthetic process  positive regulation of fractalkine biosynthetic process  positive regulation of phagocytosis  defense response to Gram-negative bacterium  induction of positive chemotaxis  defense response to virus  cell chemotaxis  extracellular exosome  protein kinase C signaling  neutrophil mediated killing of bacterium  
NDEx NetworkAZU1
Atlas of Cancer Signalling NetworkAZU1
Wikipedia pathwaysAZU1
Orthology - Evolution
OrthoDB566
GeneTree (enSembl)ENSG00000172232
Phylogenetic Trees/Animal Genes : TreeFamAZU1
HOVERGENP20160
HOGENOMP20160
Homologs : HomoloGeneAZU1
Homology/Alignments : Family Browser (UCSC)AZU1
Gene fusions - Rearrangements
Fusion : MitelmanSF3A2/AZU1 [19p13.3/19p13.3]  [t(19;19)(p13;p13)]  
Fusion: TCGA_MDACCSF3A2 19p13.3 AZU1 19p13.3 PRAD
Tumor Fusion PortalAZU1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAZU1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AZU1
dbVarAZU1
ClinVarAZU1
1000_GenomesAZU1 
Exome Variant ServerAZU1
ExAC (Exome Aggregation Consortium)ENSG00000172232
GNOMAD BrowserENSG00000172232
Genetic variants : HAPMAP566
Genomic Variants (DGV)AZU1 [DGVbeta]
DECIPHERAZU1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAZU1 
Mutations
ICGC Data PortalAZU1 
TCGA Data PortalAZU1 
Broad Tumor PortalAZU1
OASIS PortalAZU1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAZU1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAZU1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AZU1
DgiDB (Drug Gene Interaction Database)AZU1
DoCM (Curated mutations)AZU1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AZU1 (select a term)
intoGenAZU1
Cancer3DAZU1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM162815   
Orphanet
DisGeNETAZU1
MedgenAZU1
Genetic Testing Registry AZU1
NextProtP20160 [Medical]
TSGene566
GENETestsAZU1
Target ValidationAZU1
Huge Navigator AZU1 [HugePedia]
snp3D : Map Gene to Disease566
BioCentury BCIQAZU1
ClinGenAZU1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD566
Chemical/Pharm GKB GenePA25206
Clinical trialAZU1
Miscellaneous
canSAR (ICR)AZU1 (select the gene name)
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAZU1
EVEXAZU1
GoPubMedAZU1
iHOPAZU1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:27:43 CET 2017

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