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B3GAT3 (beta-1,3-glucuronyltransferase 3)

Identity

Alias_namesbeta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
Alias_symbol (synonym)GlcAT-I
Other aliasGLCATI
JDSCD
glcUAT-I
HGNC (Hugo) B3GAT3
LocusID (NCBI) 26229
Atlas_Id 60681
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62615296 and ends at 62622175 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
B3GAT3 (11q12.3) / ATP1B2 (17p13.1)B3GAT3 (11q12.3) / GANAB (11q12.3)B3GAT3 (11q12.3) / SLC8A3 (14q24.2)
SHC4 (15q21.1) / B3GAT3 (11q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)B3GAT3   923
Cards
Entrez_Gene (NCBI)B3GAT3  26229  beta-1,3-glucuronyltransferase 3
AliasesGLCATI; JDSCD; glcUAT-I
GeneCards (Weizmann)B3GAT3
Ensembl hg19 (Hinxton)ENSG00000149541 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149541 [Gene_View]  chr11:62615296-62622175 [Contig_View]  B3GAT3 [Vega]
ICGC DataPortalENSG00000149541
TCGA cBioPortalB3GAT3
AceView (NCBI)B3GAT3
Genatlas (Paris)B3GAT3
WikiGenes26229
SOURCE (Princeton)B3GAT3
Genetics Home Reference (NIH)B3GAT3
Genomic and cartography
GoldenPath hg38 (UCSC)B3GAT3  -     chr11:62615296-62622175 -  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)B3GAT3  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblB3GAT3 - 11q12.3 [CytoView hg19]  B3GAT3 - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBIB3GAT3 [Mapview hg19]  B3GAT3 [Mapview hg38]
OMIM245600   606374   
Gene and transcription
Genbank (Entrez)AB009598 AJ005865 AK075166 AK297970 AK310200
RefSeq transcript (Entrez)NM_001288721 NM_001288722 NM_001288723 NM_012200
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)B3GAT3
Cluster EST : UnigeneHs.502759 [ NCBI ]
CGAP (NCI)Hs.502759
Alternative Splicing GalleryENSG00000149541
Gene ExpressionB3GAT3 [ NCBI-GEO ]   B3GAT3 [ EBI - ARRAY_EXPRESS ]   B3GAT3 [ SEEK ]   B3GAT3 [ MEM ]
Gene Expression Viewer (FireBrowse)B3GAT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26229
GTEX Portal (Tissue expression)B3GAT3
Human Protein AtlasENSG00000149541-B3GAT3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94766   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94766  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94766
Splice isoforms : SwissVarO94766
PhosPhoSitePlusO94766
Domains : Interpro (EBI)Glyco_trans_43    Nucleotide-diphossugar_trans   
Domain families : Pfam (Sanger)Glyco_transf_43 (PF03360)   
Domain families : Pfam (NCBI)pfam03360   
Conserved Domain (NCBI)B3GAT3
DMDM Disease mutations26229
Blocks (Seattle)B3GAT3
PDB (SRS)1FGG    1KWS    3CU0   
PDB (PDBSum)1FGG    1KWS    3CU0   
PDB (IMB)1FGG    1KWS    3CU0   
PDB (RSDB)1FGG    1KWS    3CU0   
Structural Biology KnowledgeBase1FGG    1KWS    3CU0   
SCOP (Structural Classification of Proteins)1FGG    1KWS    3CU0   
CATH (Classification of proteins structures)1FGG    1KWS    3CU0   
SuperfamilyO94766
Human Protein Atlas [tissue]ENSG00000149541-B3GAT3 [tissue]
Peptide AtlasO94766
HPRD07564
IPIIPI00304331   IPI00477470   IPI00980334   IPI00978958   IPI00979750   IPI00978360   
Protein Interaction databases
DIP (DOE-UCLA)O94766
IntAct (EBI)O94766
FunCoupENSG00000149541
BioGRIDB3GAT3
STRING (EMBL)B3GAT3
ZODIACB3GAT3
Ontologies - Pathways
QuickGOO94766
Ontology : AmiGOGolgi membrane  protein binding  Golgi apparatus  cis-Golgi network  carbohydrate metabolic process  glycosaminoglycan biosynthetic process  glycosaminoglycan biosynthetic process  glycosaminoglycan biosynthetic process  protein glycosylation  heparan sulfate proteoglycan biosynthetic process  heparan sulfate proteoglycan biosynthetic process  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity  glucuronosyltransferase activity  glucuronosyltransferase activity  membrane  integral component of membrane  glycosaminoglycan metabolic process  chondroitin sulfate metabolic process  positive regulation of catalytic activity  metal ion binding  chondroitin sulfate proteoglycan biosynthetic process  chondroitin sulfate proteoglycan biosynthetic process  dermatan sulfate proteoglycan biosynthetic process  dermatan sulfate proteoglycan biosynthetic process  extracellular exosome  protein phosphatase activator activity  positive regulation of intracellular protein transport  
Ontology : EGO-EBIGolgi membrane  protein binding  Golgi apparatus  cis-Golgi network  carbohydrate metabolic process  glycosaminoglycan biosynthetic process  glycosaminoglycan biosynthetic process  glycosaminoglycan biosynthetic process  protein glycosylation  heparan sulfate proteoglycan biosynthetic process  heparan sulfate proteoglycan biosynthetic process  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity  glucuronosyltransferase activity  glucuronosyltransferase activity  membrane  integral component of membrane  glycosaminoglycan metabolic process  chondroitin sulfate metabolic process  positive regulation of catalytic activity  metal ion binding  chondroitin sulfate proteoglycan biosynthetic process  chondroitin sulfate proteoglycan biosynthetic process  dermatan sulfate proteoglycan biosynthetic process  dermatan sulfate proteoglycan biosynthetic process  extracellular exosome  protein phosphatase activator activity  positive regulation of intracellular protein transport  
Pathways : KEGGGlycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate    Glycosaminoglycan biosynthesis - heparan sulfate / heparin   
NDEx NetworkB3GAT3
Atlas of Cancer Signalling NetworkB3GAT3
Wikipedia pathwaysB3GAT3
Orthology - Evolution
OrthoDB26229
GeneTree (enSembl)ENSG00000149541
Phylogenetic Trees/Animal Genes : TreeFamB3GAT3
HOVERGENO94766
HOGENOMO94766
Homologs : HomoloGeneB3GAT3
Homology/Alignments : Family Browser (UCSC)B3GAT3
Gene fusions - Rearrangements
Tumor Fusion PortalB3GAT3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerB3GAT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)B3GAT3
dbVarB3GAT3
ClinVarB3GAT3
1000_GenomesB3GAT3 
Exome Variant ServerB3GAT3
ExAC (Exome Aggregation Consortium)ENSG00000149541
GNOMAD BrowserENSG00000149541
Genetic variants : HAPMAP26229
Genomic Variants (DGV)B3GAT3 [DGVbeta]
DECIPHERB3GAT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisB3GAT3 
Mutations
ICGC Data PortalB3GAT3 
TCGA Data PortalB3GAT3 
Broad Tumor PortalB3GAT3
OASIS PortalB3GAT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICB3GAT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDB3GAT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch B3GAT3
DgiDB (Drug Gene Interaction Database)B3GAT3
DoCM (Curated mutations)B3GAT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)B3GAT3 (select a term)
intoGenB3GAT3
Cancer3DB3GAT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM245600    606374   
Orphanet20576   
DisGeNETB3GAT3
MedgenB3GAT3
Genetic Testing Registry B3GAT3
NextProtO94766 [Medical]
TSGene26229
GENETestsB3GAT3
Target ValidationB3GAT3
Huge Navigator B3GAT3 [HugePedia]
snp3D : Map Gene to Disease26229
BioCentury BCIQB3GAT3
ClinGenB3GAT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26229
Chemical/Pharm GKB GenePA25217
Clinical trialB3GAT3
Miscellaneous
canSAR (ICR)B3GAT3 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineB3GAT3
EVEXB3GAT3
GoPubMedB3GAT3
iHOPB3GAT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:23:02 CET 2017

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