B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5)

2012-09-01  

Identity

HGNC
LOCATION
3q27.1
LOCUSID
ALIAS
B3GN-T5,beta3Gn-T5
FUSION GENES

Other Information

Locus ID:

NCBI: 84002
MIM: 615333
HGNC: 15684
Ensembl: ENSG00000176597

Variants:

dbSNP: 84002
ClinVar: 84002
TCGA: ENSG00000176597
COSMIC: B3GNT5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176597ENST00000326505Q9BYG0
ENSG00000176597ENST00000460419Q9BYG0
ENSG00000176597ENST00000464191C9IYY0
ENSG00000176597ENST00000464923C9J5K2
ENSG00000176597ENST00000465010Q9BYG0
ENSG00000176597ENST00000481531C9J368

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Glycosphingolipid biosynthesis - lacto and neolacto seriesKEGGko00601
Glycosphingolipid biosynthesis - lacto and neolacto seriesKEGGhsa00601
Metabolic pathwaysKEGGhsa01100
Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4CerKEGGhsa_M00070
Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4CerKEGGhsa_M00071
Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4CerKEGGM00070
Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4CerKEGGM00071
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-linked glycosylation of mucinsREACTOMER-HSA-913709

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
184836242008Helicobacter pylori induces beta3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl-Lewis x.38
207340642010A large-scale candidate gene association study of age at menarche and age at natural menopause.38
224118382012High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients.12

Citation

Dessen P

B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5)

Atlas Genet Cytogenet Oncol Haematol. 2012-09-01

Online version: http://atlasgeneticsoncology.org/gene/52877/b3gnt5