B4GALNT3 (beta-1,4-N-acetyl-galactosaminyltransferase 3)

2007-08-01  

Identity

HGNC
LOCATION
12p13.33
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 283358
MIM: 612220
HGNC: 24137
Ensembl: ENSG00000139044

Variants:

dbSNP: 283358
ClinVar: 283358
TCGA: ENSG00000139044
COSMIC: B4GALNT3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139044ENST00000266383Q6L9W6
ENSG00000139044ENST00000322843E9PHD9

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Metabolic pathwaysKEGGhsa01100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
258033232015New somatic mutations and WNK1-B4GALNT3 gene fusion in papillary thyroid carcinoma.24
203608442010Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest.21
167285622006Apical Golgi localization of N,N'-diacetyllactosediamine synthase, beta4GalNAc-T3, is responsible for LacdiNAc expression on gastric mucosa.0
175791162007Beta1,4-N-acetylgalactosaminyltransferase III enhances malignant phenotypes of colon cancer cells.0
180483532008A necessary and sufficient determinant for protein-selective glycosylation in vivo.0
227229372012Molecular basis for protein-specific transfer of N-acetylgalactosamine to N-linked glycans by the glycosyltransferases β1,4-N-acetylgalactosaminyl transferase 3 (β4GalNAc-T3) and β4GalNAc-T4.0
227229402012Peptide-specific transfer of N-acetylgalactosamine to O-linked glycans by the glycosyltransferases β1,4-N-acetylgalactosaminyl transferase 3 (β4GalNAc-T3) and β4GalNAc-T4.0
250032322014β1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells.0

Citation

Dessen P

B4GALNT3 (beta-1,4-N-acetyl-galactosaminyltransferase 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-08-01

Online version: http://atlasgeneticsoncology.org/gene/47694/b4galnt3