B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1)

Identity

Other names	B4GAL-T1
	DKFZp686N19253
	GGTB2
	GT1
	GTB
	MGC50983
	beta4Gal-T1
HGNC	B4GALT1
Location	9p13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	B4GALT1   924
Entrez_Gene	B4GALT1  2683  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
	Cards
GeneCards	B4GALT1
Ensembl	B4GALT1 [Search_View]   ENSG00000086062 [Gene_View]
Genatlas	B4GALT1
GeneLynx	B4GALT1
eGenome	B4GALT1
euGene	2683
	Genomic and cartography
GoldenPath	B4GALT1  -  9p13   chr9:33100639-33157356 -  9p13.3   [Description]    (hg18-March_2006)
Ensembl	B4GALT1 - 9p13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	B4GALT1
	Gene and transcription
Genbank	A23697 [ ENTREZ ]
Genbank	AK312797 [ ENTREZ ]
Genbank	AY864848 [ ENTREZ ]
Genbank	BC034244 [ ENTREZ ]
Genbank	BC035442 [ ENTREZ ]
RefSeq	NM_001497 [ SRS ]    NM_001497 [ ENTREZ ]
RefSeq	AC_000052 [ SRS ]    AC_000052 [ ENTREZ ]
RefSeq	AC_000141 [ SRS ]    AC_000141 [ ENTREZ ]
RefSeq	NC_000009 [ SRS ]    NC_000009 [ ENTREZ ]
RefSeq	NT_008413 [ SRS ]    NT_008413 [ ENTREZ ]
RefSeq	NW_001839149 [ SRS ]    NW_001839149 [ ENTREZ ]
RefSeq	NW_924062 [ SRS ]    NW_924062 [ ENTREZ ]
AceView	B4GALT1 AceView - NCBI
Unigene	Hs.651277 [ SRS ]    Hs.651277 [ NCBI ]     HS651277 [ spliceNest ]
Fast-db	4132 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P15291 [ SRS]    P15291 [ EXPASY ]     P15291 [ INTERPRO ]     P15291 [ UNIPROT ]
Interpro	IPR003859 Galactosyl_T_2 [ SRS ]    IPR003859 Galactosyl_T_2 [ EBI ]
CluSTr	P15291
Pfam	PF02709 Galactosyl_T_2 [ SRS ]    PF02709 Galactosyl_T_2 [ Sanger ]    pfam02709 [ NCBI-CDD ]
Blocks	P15291
PDB	2AE7 [ SRS ]    2AE7 [ PdbSum ],   2AE7 [ IMB ]   2AE7 [ RSDB ]
PDB	2AEC [ SRS ]    2AEC [ PdbSum ],   2AEC [ IMB ]   2AEC [ RSDB ]
PDB	2AES [ SRS ]    2AES [ PdbSum ],   2AES [ IMB ]   2AES [ RSDB ]
PDB	2AGD [ SRS ]    2AGD [ PdbSum ],   2AGD [ IMB ]   2AGD [ RSDB ]
PDB	2AH9 [ SRS ]    2AH9 [ PdbSum ],   2AH9 [ IMB ]   2AH9 [ RSDB ]
PDB	2FY7 [ SRS ]    2FY7 [ PdbSum ],   2FY7 [ IMB ]   2FY7 [ RSDB ]
PDB	2FYA [ SRS ]    2FYA [ PdbSum ],   2FYA [ IMB ]   2FYA [ RSDB ]
PDB	2FYB [ SRS ]    2FYB [ PdbSum ],   2FYB [ IMB ]   2FYB [ RSDB ]
HPRD	00659
	Protein Interaction databases
DIP	P15291
IntAct	P15291
	Polymorphism : SNP, mutations, diseases
OMIM	137060;607091    [ map ]
GENECLINICS	137060;607091
SNP	B4GALT1 [dbSNP-NCBI]
SNP	NM_001497 [SNP-NCI]
SNP	B4GALT1 [GeneSNPs - Utah]  B4GALT1] [HGBASE - SRS]
HAPMAP	B4GALT1 [HAPMAP]
HGMD	B4GALT1
	General knowledge
Family Browser	B4GALT1 [UCSC Family Browser]
SOURCE	NM_001497
SMD	Hs.651277
SAGE	Hs.651277
Enzyme	2.4.1.- [ Enzyme-Expasy ]   2.4.1.- [ Enzyme-SRS ]   2.4.1.- [ IntEnz-EBI ]   2.4.1.- [ BRENDA ]   2.4.1.- [ KEGG ]   2.4.1.- [ WIT ]
GO	Golgi trans cisterna [Amigo]  Golgi trans cisterna
GO	epithelial cell development [Amigo]  epithelial cell development
GO	acute inflammatory response [Amigo]  acute inflammatory response
GO	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [Amigo]  beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
GO	N-acetyllactosamine synthase activity [Amigo]  N-acetyllactosamine synthase activity
GO	lactose synthase activity [Amigo]  lactose synthase activity
GO	extracellular region [Amigo]  extracellular region
GO	Golgi apparatus [Amigo]  Golgi apparatus
GO	plasma membrane [Amigo]  plasma membrane
GO	carbohydrate metabolic process [Amigo]  carbohydrate metabolic process
GO	lactose biosynthetic process [Amigo]  lactose biosynthetic process
GO	galactose metabolic process [Amigo]  galactose metabolic process
GO	protein amino acid terminal N-glycosylation [Amigo]  protein amino acid terminal N-glycosylation
GO	cell adhesion [Amigo]  cell adhesion
GO	binding of sperm to zona pellucida [Amigo]  binding of sperm to zona pellucida
GO	penetration of zona pellucida [Amigo]  penetration of zona pellucida
GO	cytoskeletal protein binding [Amigo]  cytoskeletal protein binding
GO	negative regulation of cell proliferation [Amigo]  negative regulation of cell proliferation
GO	glycoprotein biosynthetic process [Amigo]  glycoprotein biosynthetic process
GO	oligosaccharide biosynthetic process [Amigo]  oligosaccharide biosynthetic process
GO	oligosaccharide biosynthetic process [Amigo]  oligosaccharide biosynthetic process
GO	external side of plasma membrane [Amigo]  external side of plasma membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	basolateral plasma membrane [Amigo]  basolateral plasma membrane
GO	transferase activity, transferring glycosyl groups [Amigo]  transferase activity, transferring glycosyl groups
GO	desmosome [Amigo]  desmosome
GO	glycocalyx [Amigo]  glycocalyx
GO	manganese ion binding [Amigo]  manganese ion binding
GO	extracellular matrix organization and biogenesis [Amigo]  extracellular matrix organization and biogenesis
GO	mammary gland development [Amigo]  mammary gland development
GO	brush border membrane [Amigo]  brush border membrane
GO	development of secondary sexual characteristics [Amigo]  development of secondary sexual characteristics
GO	metal ion binding [Amigo]  metal ion binding
GO	branching morphogenesis of a tube [Amigo]  branching morphogenesis of a tube
GO	leukocyte migration [Amigo]  leukocyte migration
GO	regulation of cell motility [Amigo]  regulation of cell motility
GO	regulation of acrosome reaction [Amigo]  regulation of acrosome reaction
GO	positive regulation of epithelial cell proliferation involved in wound healing [Amigo]  positive regulation of epithelial cell proliferation involved in wound healing
GO	angiogenesis involved in wound healing [Amigo]  angiogenesis involved in wound healing
GO	positive regulation of apoptosis involved in mammary gland involution [Amigo]  positive regulation of apoptosis involved in mammary gland involution
KEGG	Galactose metabolism
KEGG	N-Glycan biosynthesis
KEGG	Keratan sulfate biosynthesis
KEGG	Glycosphingolipid biosynthesis - neo-lactoseries
KEGG	Glycan structures - biosynthesis 1
KEGG	Glycan structures - biosynthesis 2
PubGene	B4GALT1
TreeFam	B4GALT1
CTD	2683 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	B4GALT1 Related clones (RZPD - Berlin)
	PubMed
PubMed	36 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:01:30 2008