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B4GALT3 (beta-1,4-galactosyltransferase 3)

Identity

Alias_namesUDP-Gal:betaGlcNAc beta 1
Alias_symbol (synonym)beta4Gal-T3
Other alias
HGNC (Hugo) B4GALT3
LocusID (NCBI) 8703
Atlas_Id 54844
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 161171310 and ends at 161177968 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
B4GALT3 (1q23.3) / BCAS3 (17q23.2)B4GALT3 (1q23.3) / TPM3 (1q21.3)B4GALT3 1q23.3 / BCAS3 17q23.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  dup(1q) in ALL


External links

Nomenclature
HGNC (Hugo)B4GALT3   926
Cards
Entrez_Gene (NCBI)B4GALT3  8703  beta-1,4-galactosyltransferase 3
Aliasesbeta4Gal-T3
GeneCards (Weizmann)B4GALT3
Ensembl hg19 (Hinxton)ENSG00000158850 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158850 [Gene_View]  chr1:161171310-161177968 [Contig_View]  B4GALT3 [Vega]
ICGC DataPortalENSG00000158850
TCGA cBioPortalB4GALT3
AceView (NCBI)B4GALT3
Genatlas (Paris)B4GALT3
WikiGenes8703
SOURCE (Princeton)B4GALT3
Genetics Home Reference (NIH)B4GALT3
Genomic and cartography
GoldenPath hg38 (UCSC)B4GALT3  -     chr1:161171310-161177968 -  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)B4GALT3  -     1q23.3   [Description]    (hg19-Feb_2009)
EnsemblB4GALT3 - 1q23.3 [CytoView hg19]  B4GALT3 - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBIB4GALT3 [Mapview hg19]  B4GALT3 [Mapview hg38]
OMIM604014   
Gene and transcription
Genbank (Entrez)AB024435 AF038661 AK023311 AK056851 AK092493
RefSeq transcript (Entrez)NM_001199873 NM_001199874 NM_003779
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)B4GALT3
Cluster EST : UnigeneHs.741821 [ NCBI ]
CGAP (NCI)Hs.741821
Alternative Splicing GalleryENSG00000158850
Gene ExpressionB4GALT3 [ NCBI-GEO ]   B4GALT3 [ EBI - ARRAY_EXPRESS ]   B4GALT3 [ SEEK ]   B4GALT3 [ MEM ]
Gene Expression Viewer (FireBrowse)B4GALT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8703
GTEX Portal (Tissue expression)B4GALT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60512   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60512  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60512
Splice isoforms : SwissVarO60512
Catalytic activity : Enzyme2.4.1.- [ Enzyme-Expasy ]   2.4.1.-2.4.1.- [ IntEnz-EBI ]   2.4.1.- [ BRENDA ]   2.4.1.- [ KEGG ]   
PhosPhoSitePlusO60512
Domains : Interpro (EBI)Galactosyl_T    Galactosyl_T_C    Galactosyl_T_N    Nucleotide-diphossugar_trans   
Domain families : Pfam (Sanger)Glyco_transf_7C (PF02709)    Glyco_transf_7N (PF13733)   
Domain families : Pfam (NCBI)pfam02709    pfam13733   
Conserved Domain (NCBI)B4GALT3
DMDM Disease mutations8703
Blocks (Seattle)B4GALT3
SuperfamilyO60512
Human Protein AtlasENSG00000158850
Peptide AtlasO60512
HPRD04929
IPIIPI00873139   IPI01011505   IPI00903154   IPI00746600   IPI00027090   IPI00654619   
Protein Interaction databases
DIP (DOE-UCLA)O60512
IntAct (EBI)O60512
FunCoupENSG00000158850
BioGRIDB4GALT3
STRING (EMBL)B4GALT3
ZODIACB4GALT3
Ontologies - Pathways
QuickGOO60512
Ontology : AmiGOGolgi membrane  beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity  N-acetyllactosamine synthase activity  Golgi apparatus  cytosol  carbohydrate metabolic process  protein glycosylation  galactosyltransferase activity  integral component of membrane  keratan sulfate biosynthetic process  Golgi cisterna membrane  metal ion binding  extracellular exosome  
Ontology : EGO-EBIGolgi membrane  beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity  N-acetyllactosamine synthase activity  Golgi apparatus  cytosol  carbohydrate metabolic process  protein glycosylation  galactosyltransferase activity  integral component of membrane  keratan sulfate biosynthetic process  Golgi cisterna membrane  metal ion binding  extracellular exosome  
Pathways : KEGGN-Glycan biosynthesis    Other types of O-glycan biosynthesis    Glycosaminoglycan biosynthesis - keratan sulfate    Glycosphingolipid biosynthesis - lacto and neolacto series   
NDEx NetworkB4GALT3
Atlas of Cancer Signalling NetworkB4GALT3
Wikipedia pathwaysB4GALT3
Orthology - Evolution
OrthoDB8703
GeneTree (enSembl)ENSG00000158850
Phylogenetic Trees/Animal Genes : TreeFamB4GALT3
HOVERGENO60512
HOGENOMO60512
Homologs : HomoloGeneB4GALT3
Homology/Alignments : Family Browser (UCSC)B4GALT3
Gene fusions - Rearrangements
Fusion : MitelmanB4GALT3/BCAS3 [1q23.3/17q23.2]  
Fusion : MitelmanB4GALT3/TPM3 [1q23.3/1q21.3]  [t(1;1)(q21;q23)]  
Fusion: TCGAB4GALT3 1q23.3 BCAS3 17q23.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerB4GALT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)B4GALT3
dbVarB4GALT3
ClinVarB4GALT3
1000_GenomesB4GALT3 
Exome Variant ServerB4GALT3
ExAC (Exome Aggregation Consortium)B4GALT3 (select the gene name)
Genetic variants : HAPMAP8703
Genomic Variants (DGV)B4GALT3 [DGVbeta]
DECIPHERB4GALT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisB4GALT3 
Mutations
ICGC Data PortalB4GALT3 
TCGA Data PortalB4GALT3 
Broad Tumor PortalB4GALT3
OASIS PortalB4GALT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICB4GALT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDB4GALT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch B4GALT3
DgiDB (Drug Gene Interaction Database)B4GALT3
DoCM (Curated mutations)B4GALT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)B4GALT3 (select a term)
intoGenB4GALT3
Cancer3DB4GALT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604014   
Orphanet
MedgenB4GALT3
Genetic Testing Registry B4GALT3
NextProtO60512 [Medical]
TSGene8703
GENETestsB4GALT3
Target ValidationB4GALT3
Huge Navigator B4GALT3 [HugePedia]
snp3D : Map Gene to Disease8703
BioCentury BCIQB4GALT3
ClinGenB4GALT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8703
Chemical/Pharm GKB GenePA25225
Clinical trialB4GALT3
Miscellaneous
canSAR (ICR)B4GALT3 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineB4GALT3
EVEXB4GALT3
GoPubMedB4GALT3
iHOPB4GALT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:47:44 CEST 2017

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