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BAG2 (BAG cochaperone 2)

Identity

Alias (NCBI)BAG-2
dJ417I1.2
HGNC (Hugo) BAG2
HGNC Previous nameBCL2 associated athanogene 2
LocusID (NCBI) 9532
Atlas_Id 43159
Location 6p12.1  [Link to chromosome band 6p12]
Location_base_pair Starts at 57172326 and ends at 57189833 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BAG2 (6p11.2) / BAG2 (6p11.2)BAG2 (6p11.2) / RNF114 (20q13.13)BAG2 (6p11.2) / ZNF451 (6p12.1)
BAG2 6p11.2 / RNF114 20q13.13BAG2 6p11.2 / ZNF451 6p12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)BAG2   938
Cards
Entrez_Gene (NCBI)BAG2    BAG cochaperone 2
AliasesBAG-2; dJ417I1.2
GeneCards (Weizmann)BAG2
Ensembl hg19 (Hinxton)ENSG00000112208 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112208 [Gene_View]  ENSG00000112208 [Sequence]  chr6:57172326-57189833 [Contig_View]  BAG2 [Vega]
ICGC DataPortalENSG00000112208
TCGA cBioPortalBAG2
AceView (NCBI)BAG2
Genatlas (Paris)BAG2
SOURCE (Princeton)BAG2
Genetics Home Reference (NIH)BAG2
Genomic and cartography
GoldenPath hg38 (UCSC)BAG2  -     chr6:57172326-57189833 +  6p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BAG2  -     6p12.1   [Description]    (hg19-Feb_2009)
GoldenPathBAG2 - 6p12.1 [CytoView hg19]  BAG2 - 6p12.1 [CytoView hg38]
ImmunoBaseENSG00000112208
Genome Data Viewer NCBIBAG2 [Mapview hg19]  
OMIM603882   
Gene and transcription
Genbank (Entrez)AF095192 AK001015 AK023735 AK301934 AL050287
RefSeq transcript (Entrez)NM_004282
Consensus coding sequences : CCDS (NCBI)BAG2
Gene ExpressionBAG2 [ NCBI-GEO ]   BAG2 [ EBI - ARRAY_EXPRESS ]   BAG2 [ SEEK ]   BAG2 [ MEM ]
Gene Expression Viewer (FireBrowse)BAG2 [ Firebrowse - Broad ]
GenevisibleExpression of BAG2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9532
GTEX Portal (Tissue expression)BAG2
Human Protein AtlasENSG00000112208-BAG2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95816   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95816  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95816
PhosPhoSitePlusO95816
Domaine pattern : Prosite (Expaxy)BAG (PS51035)   
Domains : Interpro (EBI)BAG2    BAG_domain   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)BAG (SM00264)  
Conserved Domain (NCBI)BAG2
SuperfamilyO95816
AlphaFold pdb e-kbO95816   
Human Protein Atlas [tissue]ENSG00000112208-BAG2 [tissue]
HPRD04859
Protein Interaction databases
DIP (DOE-UCLA)O95816
IntAct (EBI)O95816
BioGRIDBAG2
STRING (EMBL)BAG2
ZODIACBAG2
Ontologies - Pathways
QuickGOO95816
Ontology : AmiGOadenyl-nucleotide exchange factor activity  adenyl-nucleotide exchange factor activity  protein binding  cytosol  microtubule  protein folding  positive regulation of protein processing  protein metabolic process  axon  dendrite  heat shock protein binding  negative regulation of protein ubiquitination  negative regulation of protein ubiquitination  ubiquitin protein ligase binding  negative regulation of protein binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  identical protein binding  ion channel binding  tau protein binding  protein stabilization  protein stabilization  chaperone binding  chaperone complex  regulation of cellular response to heat  dendritic microtubule  positive regulation of proteasomal protein catabolic process  negative regulation of ubiquitin protein ligase activity  
Ontology : EGO-EBIadenyl-nucleotide exchange factor activity  adenyl-nucleotide exchange factor activity  protein binding  cytosol  microtubule  protein folding  positive regulation of protein processing  protein metabolic process  axon  dendrite  heat shock protein binding  negative regulation of protein ubiquitination  negative regulation of protein ubiquitination  ubiquitin protein ligase binding  negative regulation of protein binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  identical protein binding  ion channel binding  tau protein binding  protein stabilization  protein stabilization  chaperone binding  chaperone complex  regulation of cellular response to heat  dendritic microtubule  positive regulation of proteasomal protein catabolic process  negative regulation of ubiquitin protein ligase activity  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkBAG2
Atlas of Cancer Signalling NetworkBAG2
Wikipedia pathwaysBAG2
Orthology - Evolution
OrthoDB9532
GeneTree (enSembl)ENSG00000112208
Phylogenetic Trees/Animal Genes : TreeFamBAG2
Homologs : HomoloGeneBAG2
Homology/Alignments : Family Browser (UCSC)BAG2
Gene fusions - Rearrangements
Fusion : MitelmanBAG2/RNF114 [6p11.2/20q13.13]  
Fusion : MitelmanBAG2/ZNF451 [6p11.2/6p12.1]  
Fusion : QuiverBAG2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBAG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BAG2
dbVarBAG2
ClinVarBAG2
MonarchBAG2
1000_GenomesBAG2 
Exome Variant ServerBAG2
GNOMAD BrowserENSG00000112208
Varsome BrowserBAG2
ACMGBAG2 variants
VarityO95816
Genomic Variants (DGV)BAG2 [DGVbeta]
DECIPHERBAG2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBAG2 
Mutations
ICGC Data PortalBAG2 
TCGA Data PortalBAG2 
Broad Tumor PortalBAG2
OASIS PortalBAG2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBAG2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DBAG2
Mutations and Diseases : HGMDBAG2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaBAG2
DgiDB (Drug Gene Interaction Database)BAG2
DoCM (Curated mutations)BAG2
CIViC (Clinical Interpretations of Variants in Cancer)BAG2
Cancer3DBAG2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603882   
Orphanet
DisGeNETBAG2
MedgenBAG2
Genetic Testing Registry BAG2
NextProtO95816 [Medical]
GENETestsBAG2
Target ValidationBAG2
Huge Navigator BAG2 [HugePedia]
ClinGenBAG2
Clinical trials, drugs, therapy
MyCancerGenomeBAG2
Protein Interactions : CTDBAG2
Pharm GKB GenePA25238
PharosO95816
Clinical trialBAG2
Miscellaneous
canSAR (ICR)BAG2
HarmonizomeBAG2
DataMed IndexBAG2
Probes
Litterature
PubMed165 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXBAG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:00:52 CEST 2021

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