| BAG4 (8p11.23) / FGFR1 (8p11.23) | BAG4 (8p11.23) / NEDD8 (14q12) | BAG4 (8p11.23) / NEDD8-MDP1 (14q12) |
|
BAG4 (8p11.23) / TP53INP1 (8q22.1) | BAG4 (8p11.23) / ZMAT4 (8p11.21) | BAG4 8p11.23 / FGFR1 8p11.23 |
|
BAG4 8p11.23 / NEDD8 14q12 | BAG4 8p11.23 / NEDD8-MDP1 14q12 | BAG4 8p11.23 / TP53INP1 8q22.1 |
|
BAG4 8p11.23 / ZMAT4 8p11.21 |
| Nomenclature |
HGNC (Hugo) | BAG4 940 |
| Cards |
Entrez_Gene (NCBI) | BAG4 9530 BCL2 associated athanogene 4 |
Aliases | BAG-4; SODD |
GeneCards (Weizmann) | BAG4 |
Ensembl hg19 (Hinxton) | ENSG00000156735 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000156735 [Gene_View] chr8:38176588-38213301 [Contig_View] BAG4 [Vega] |
ICGC DataPortal | ENSG00000156735 |
TCGA cBioPortal | BAG4 |
AceView (NCBI) | BAG4 |
Genatlas (Paris) | BAG4 |
WikiGenes | 9530 |
SOURCE (Princeton) | BAG4 |
Genetics Home Reference (NIH) | BAG4 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | BAG4 - chr8:38176588-38213301 + 8p11.23 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | BAG4 - 8p11.23 [Description] (hg19-Feb_2009) |
Ensembl | BAG4 - 8p11.23 [CytoView hg19] BAG4 - 8p11.23 [CytoView hg38] |
Mapping of homologs : NCBI | BAG4 [Mapview hg19] BAG4 [Mapview hg38] |
OMIM | 603884 |
| Gene and transcription |
Genbank (Entrez) | AF095194 AF111116 AI640615 AK304072 AK314020 |
RefSeq transcript (Entrez) | NM_001204878 NM_004874 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | BAG4 |
Cluster EST : Unigene | Hs.194726 [ NCBI ] |
CGAP (NCI) | Hs.194726 |
Alternative Splicing Gallery | ENSG00000156735 |
Gene Expression | BAG4 [ NCBI-GEO ] BAG4 [ EBI - ARRAY_EXPRESS ]
BAG4 [ SEEK ] BAG4 [ MEM ] |
Gene Expression Viewer (FireBrowse) | BAG4 [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 9530 |
GTEX Portal (Tissue expression) | BAG4 |
Human Protein Atlas | ENSG00000156735-BAG4 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | O95429 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | O95429 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | O95429 |
Splice isoforms : SwissVar | O95429 |
PhosPhoSitePlus | O95429 |
Domaine pattern : Prosite (Expaxy) | BAG (PS51035) |
Domains : Interpro (EBI) | BAG_domain |
Domain families : Pfam (Sanger) | BAG (PF02179) |
Domain families : Pfam (NCBI) | pfam02179 |
Domain families : Smart (EMBL) | BAG (SM00264) |
Conserved Domain (NCBI) | BAG4 |
DMDM Disease mutations | 9530 |
Blocks (Seattle) | BAG4 |
PDB (SRS) | 1M62 1M7K |
PDB (PDBSum) | 1M62 1M7K |
PDB (IMB) | 1M62 1M7K |
PDB (RSDB) | 1M62 1M7K |
Structural Biology KnowledgeBase | 1M62 1M7K |
SCOP (Structural Classification of Proteins) | 1M62 1M7K |
CATH (Classification of proteins structures) | 1M62 1M7K |
Superfamily | O95429 |
Human Protein Atlas [tissue] | ENSG00000156735-BAG4 [tissue] |
Peptide Atlas | O95429 |
HPRD | 04861 |
IPI | IPI00030695 IPI00798092 IPI00982893 |
| Protein Interaction databases |
DIP (DOE-UCLA) | O95429 |
IntAct (EBI) | O95429 |
FunCoup | ENSG00000156735 |
BioGRID | BAG4 |
STRING (EMBL) | BAG4 |
ZODIAC | BAG4 |
| Ontologies - Pathways |
QuickGO | O95429 |
Ontology : AmiGO | adenyl-nucleotide exchange factor activity RNA binding signal transducer activity, downstream of receptor protein binding nucleus cytosol cytosol plasma membrane protein folding positive regulation of fibroblast migration positive regulation of actin filament polymerization ubiquitin protein ligase binding positive regulation of peptidyl-serine phosphorylation tumor necrosis factor-mediated signaling pathway negative regulation of apoptotic process positive regulation of cell adhesion chaperone binding protein heterooligomerization positive regulation of stress fiber assembly positive regulation of protein kinase B signaling cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus protein localization to plasma membrane negative regulation of mRNA modification ruffle assembly regulation of cellular response to heat negative regulation of protein targeting to mitochondrion negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity |
Ontology : EGO-EBI | adenyl-nucleotide exchange factor activity RNA binding signal transducer activity, downstream of receptor protein binding nucleus cytosol cytosol plasma membrane protein folding positive regulation of fibroblast migration positive regulation of actin filament polymerization ubiquitin protein ligase binding positive regulation of peptidyl-serine phosphorylation tumor necrosis factor-mediated signaling pathway negative regulation of apoptotic process positive regulation of cell adhesion chaperone binding protein heterooligomerization positive regulation of stress fiber assembly positive regulation of protein kinase B signaling cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus protein localization to plasma membrane negative regulation of mRNA modification ruffle assembly regulation of cellular response to heat negative regulation of protein targeting to mitochondrion negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity |
Pathways : BIOCARTA | SODD/TNFR1 Signaling Pathway [Genes] HIV-I Nef: negative effector of Fas and TNF [Genes] TNFR1 Signaling Pathway [Genes] |
NDEx Network | BAG4 |
Atlas of Cancer Signalling Network | BAG4 |
Wikipedia pathways | BAG4 |
| Orthology - Evolution |
OrthoDB | 9530 |
GeneTree (enSembl) | ENSG00000156735 |
Phylogenetic Trees/Animal Genes : TreeFam | BAG4 |
HOVERGEN | O95429 |
HOGENOM | O95429 |
Homologs : HomoloGene | BAG4 |
Homology/Alignments : Family Browser (UCSC) | BAG4 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | BAG4/FGFR1 [8p11.23/8p11.23]   |
Fusion : Mitelman | BAG4/NEDD8 [8p11.23/14q12]  [t(8;14)(p11;q12)] |
Fusion : Mitelman | BAG4/NEDD8-MDP1 [8p11.23/14q12]  [t(8;14)(p11;q12)] |
Fusion : Mitelman | BAG4/TP53INP1 [8p11.23/8q22.1]  [t(8;8)(p11;q22)] |
Fusion : Mitelman | BAG4/ZMAT4 [8p11.23/8p11.21]  [t(8;8)(p11;p11)] |
Fusion: TCGA_MDACC | BAG4 8p11.23 FGFR1 8p11.23 LUSC |
Fusion: TCGA_MDACC | BAG4 8p11.23 NEDD8 14q12 BRCA |
Fusion: TCGA_MDACC | BAG4 8p11.23 NEDD8-MDP1 14q12 BRCA |
Fusion: TCGA_MDACC | BAG4 8p11.23 TP53INP1 8q22.1 BRCA |
Fusion: TCGA_MDACC | BAG4 8p11.23 ZMAT4 8p11.21 BRCA |
Fusion Portal | BAG4 8p11.23 FGFR1 8p11.23 LUSC |
Fusion Portal | BAG4 8p11.23 NEDD8 14q12 BRCA |
Fusion Portal | BAG4 8p11.23 NEDD8-MDP1 14q12 BRCA |
Fusion Portal | BAG4 8p11.23 TP53INP1 8q22.1 BRCA |
Fusion Portal | BAG4 8p11.23 ZMAT4 8p11.21 BRCA |
Fusion : Quiver | BAG4 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | BAG4 [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | BAG4 |
dbVar | BAG4 |
ClinVar | BAG4 |
1000_Genomes | BAG4 |
Exome Variant Server | BAG4 |
ExAC (Exome Aggregation Consortium) | ENSG00000156735 |
GNOMAD Browser | ENSG00000156735 |
Genetic variants : HAPMAP | 9530 |
Genomic Variants (DGV) | BAG4 [DGVbeta] |
DECIPHER | BAG4 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | BAG4 |
| Mutations |
ICGC Data Portal | BAG4 |
TCGA Data Portal | BAG4 |
Broad Tumor Portal | BAG4 |
OASIS Portal | BAG4 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | BAG4 [overview] [genome browser] [tissue] [distribution] |
Mutations and Diseases : HGMD | BAG4 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search BAG4 |
DgiDB (Drug Gene Interaction Database) | BAG4 |
DoCM (Curated mutations) | BAG4 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | BAG4 (select a term) |
intoGen | BAG4 |
Cancer3D | BAG4(select the gene name) |
Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 603884 |
Orphanet | |
DisGeNET | BAG4 |
Medgen | BAG4 |
Genetic Testing Registry | BAG4
|
NextProt | O95429 [Medical] |
TSGene | 9530 |
GENETests | BAG4 |
Target Validation | BAG4 |
Huge Navigator |
BAG4 [HugePedia] |
snp3D : Map Gene to Disease | 9530 |
BioCentury BCIQ | BAG4 |
ClinGen | BAG4 |
| Clinical trials, drugs, therapy |
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Chemical/Protein Interactions : CTD | 9530 |
Chemical/Pharm GKB Gene | PA25240 |
Clinical trial | BAG4 |
| Miscellaneous |
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canSAR (ICR) | BAG4 (select the gene name) |
| Probes |
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| Litterature |
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PubMed | 40 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | BAG4 |
EVEX | BAG4 |
GoPubMed | BAG4 |
iHOP | BAG4 |