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BAIAP2 (BAI1 associated protein 2)

Identity

Alias_namesBAI1-associated protein 2
Alias_symbol (synonym)BAP2
IRSp53
Other aliasFLAF3
IRSP53
HGNC (Hugo) BAIAP2
LocusID (NCBI) 10458
Atlas_Id 51548
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 81035147 and ends at 81117432 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AC110285.1 () / BAIAP2 (17q25.3)ADRBK1 (11q13.2) / BAIAP2 (17q25.3)BAIAP2 (17q25.3) / PSMD12 (17q24.2)
BAIAP2 (17q25.3) / SLC16A3 (17q25.3)BAIAP2 (17q25.3) / SLC38A10 (17q25.3)BAIAP2 (17q25.3) / TBCD (17q25.3)
NLE1 (17q12) / BAIAP2 (17q25.3)RNF213 (17q25.3) / BAIAP2 (17q25.3)TIMM13 (19p13.3) / BAIAP2 (17q25.3)
TMSB10 (2p11.2) / BAIAP2 (17q25.3)USMG5 (10q24.33) / BAIAP2 (17q25.3)AC110285.1 BAIAP2 17q25.3
ADRBK1 11q13.2 / BAIAP2 17q25.3BAIAP2 17q25.3 / TBCD 17q25.3NLE1 17q12 / BAIAP2 17q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BAIAP2   947
Cards
Entrez_Gene (NCBI)BAIAP2  10458  BAI1 associated protein 2
AliasesBAP2; FLAF3; IRSP53
GeneCards (Weizmann)BAIAP2
Ensembl hg19 (Hinxton)ENSG00000175866 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175866 [Gene_View]  chr17:81035147-81117432 [Contig_View]  BAIAP2 [Vega]
ICGC DataPortalENSG00000175866
TCGA cBioPortalBAIAP2
AceView (NCBI)BAIAP2
Genatlas (Paris)BAIAP2
WikiGenes10458
SOURCE (Princeton)BAIAP2
Genetics Home Reference (NIH)BAIAP2
Genomic and cartography
GoldenPath hg38 (UCSC)BAIAP2  -     chr17:81035147-81117432 +  17q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BAIAP2  -     17q25.3   [Description]    (hg19-Feb_2009)
EnsemblBAIAP2 - 17q25.3 [CytoView hg19]  BAIAP2 - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBIBAIAP2 [Mapview hg19]  BAIAP2 [Mapview hg38]
OMIM605475   
Gene and transcription
Genbank (Entrez)AB015019 AB015020 AB017119 AB017120 AK023688
RefSeq transcript (Entrez)NM_001144888 NM_006340 NM_017450 NM_017451
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BAIAP2
Cluster EST : UnigeneHs.128316 [ NCBI ]
CGAP (NCI)Hs.128316
Alternative Splicing GalleryENSG00000175866
Gene ExpressionBAIAP2 [ NCBI-GEO ]   BAIAP2 [ EBI - ARRAY_EXPRESS ]   BAIAP2 [ SEEK ]   BAIAP2 [ MEM ]
Gene Expression Viewer (FireBrowse)BAIAP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10458
GTEX Portal (Tissue expression)BAIAP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UQB8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UQB8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UQB8
Splice isoforms : SwissVarQ9UQB8
PhosPhoSitePlusQ9UQB8
Domaine pattern : Prosite (Expaxy)IMD (PS51338)    SH3 (PS50002)   
Domains : Interpro (EBI)I-BAR_dom    IRSp53    IRSp53/IRTKS/Pinkbar    SH3_domain   
Domain families : Pfam (Sanger)IMD (PF08397)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam08397    pfam14604   
Domain families : Smart (EMBL)SH3 (SM00326)  
Conserved Domain (NCBI)BAIAP2
DMDM Disease mutations10458
Blocks (Seattle)BAIAP2
PDB (SRS)1WDZ    1Y2O    2YKT    3RNJ    4JS0   
PDB (PDBSum)1WDZ    1Y2O    2YKT    3RNJ    4JS0   
PDB (IMB)1WDZ    1Y2O    2YKT    3RNJ    4JS0   
PDB (RSDB)1WDZ    1Y2O    2YKT    3RNJ    4JS0   
Structural Biology KnowledgeBase1WDZ    1Y2O    2YKT    3RNJ    4JS0   
SCOP (Structural Classification of Proteins)1WDZ    1Y2O    2YKT    3RNJ    4JS0   
CATH (Classification of proteins structures)1WDZ    1Y2O    2YKT    3RNJ    4JS0   
SuperfamilyQ9UQB8
Human Protein AtlasENSG00000175866
Peptide AtlasQ9UQB8
HPRD05686
IPIIPI00299088   IPI00644120   IPI00647603   IPI00185159   IPI00180292   IPI00642333   IPI00902640   IPI00910507   IPI00909413   IPI01010648   
Protein Interaction databases
DIP (DOE-UCLA)Q9UQB8
IntAct (EBI)Q9UQB8
FunCoupENSG00000175866
BioGRIDBAIAP2
STRING (EMBL)BAIAP2
ZODIACBAIAP2
Ontologies - Pathways
QuickGOQ9UQB8
Ontology : AmiGOtranscription cofactor binding  ruffle  protein binding  cytoplasm  rough endoplasmic reticulum  Golgi apparatus  cytosol  cytosol  microtubule  plasma membrane  cell-cell adherens junction  plasma membrane organization  axonogenesis  brain development  protein C-terminus binding  cytoskeletal adaptor activity  insulin receptor signaling pathway  regulation of cell shape  response to bacterium  postsynaptic density  actin cytoskeleton  dendrite development  secretory granule  PDZ domain binding  filopodium  positive regulation of actin filament polymerization  regulation of actin cytoskeleton organization  protein localization to synapse  Fc-gamma receptor signaling pathway involved in phagocytosis  identical protein binding  neuronal cell body  dendritic shaft  neuron projection terminus  vascular endothelial growth factor receptor signaling pathway  regulation of synaptic plasticity  actin filament bundle assembly  actin filament bundle assembly  actin crosslink formation  actin crosslink formation  excitatory synapse  positive regulation of dendritic spine morphogenesis  neuron projection branch point  dendritic spine cytoplasm  extracellular exosome  proline-rich region binding  cellular response to epidermal growth factor stimulus  synaptic membrane  scaffold protein binding  cell-cell adhesion  cadherin binding involved in cell-cell adhesion  presynapse  cellular response to L-glutamate  positive regulation of actin cytoskeleton reorganization  positive regulation of excitatory postsynaptic potential  
Ontology : EGO-EBItranscription cofactor binding  ruffle  protein binding  cytoplasm  rough endoplasmic reticulum  Golgi apparatus  cytosol  cytosol  microtubule  plasma membrane  cell-cell adherens junction  plasma membrane organization  axonogenesis  brain development  protein C-terminus binding  cytoskeletal adaptor activity  insulin receptor signaling pathway  regulation of cell shape  response to bacterium  postsynaptic density  actin cytoskeleton  dendrite development  secretory granule  PDZ domain binding  filopodium  positive regulation of actin filament polymerization  regulation of actin cytoskeleton organization  protein localization to synapse  Fc-gamma receptor signaling pathway involved in phagocytosis  identical protein binding  neuronal cell body  dendritic shaft  neuron projection terminus  vascular endothelial growth factor receptor signaling pathway  regulation of synaptic plasticity  actin filament bundle assembly  actin filament bundle assembly  actin crosslink formation  actin crosslink formation  excitatory synapse  positive regulation of dendritic spine morphogenesis  neuron projection branch point  dendritic spine cytoplasm  extracellular exosome  proline-rich region binding  cellular response to epidermal growth factor stimulus  synaptic membrane  scaffold protein binding  cell-cell adhesion  cadherin binding involved in cell-cell adhesion  presynapse  cellular response to L-glutamate  positive regulation of actin cytoskeleton reorganization  positive regulation of excitatory postsynaptic potential  
Pathways : BIOCARTARho cell motility signaling pathway [Genes]   
Pathways : KEGGAdherens junction    Regulation of actin cytoskeleton   
NDEx NetworkBAIAP2
Atlas of Cancer Signalling NetworkBAIAP2
Wikipedia pathwaysBAIAP2
Orthology - Evolution
OrthoDB10458
GeneTree (enSembl)ENSG00000175866
Phylogenetic Trees/Animal Genes : TreeFamBAIAP2
HOVERGENQ9UQB8
HOGENOMQ9UQB8
Homologs : HomoloGeneBAIAP2
Homology/Alignments : Family Browser (UCSC)BAIAP2
Gene fusions - Rearrangements
Fusion : MitelmanADRBK1/BAIAP2 [11q13.2/17q25.3]  [t(11;17)(q13;q25)]  
Fusion : MitelmanBAIAP2/TBCD [17q25.3/17q25.3]  [t(17;17)(q25;q25)]  
Fusion : MitelmanNLE1/BAIAP2 [17q12/17q25.3]  [t(17;17)(q12;q25)]  
Fusion: TCGAAC110285.1 BAIAP2 17q25.3 BRCA LGG
Fusion: TCGAADRBK1 11q13.2 BAIAP2 17q25.3 BRCA
Fusion: TCGABAIAP2 17q25.3 TBCD 17q25.3 HNSC
Fusion: TCGANLE1 17q12 BAIAP2 17q25.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBAIAP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BAIAP2
dbVarBAIAP2
ClinVarBAIAP2
1000_GenomesBAIAP2 
Exome Variant ServerBAIAP2
ExAC (Exome Aggregation Consortium)BAIAP2 (select the gene name)
Genetic variants : HAPMAP10458
Genomic Variants (DGV)BAIAP2 [DGVbeta]
DECIPHERBAIAP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBAIAP2 
Mutations
ICGC Data PortalBAIAP2 
TCGA Data PortalBAIAP2 
Broad Tumor PortalBAIAP2
OASIS PortalBAIAP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBAIAP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBAIAP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BAIAP2
DgiDB (Drug Gene Interaction Database)BAIAP2
DoCM (Curated mutations)BAIAP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BAIAP2 (select a term)
intoGenBAIAP2
Cancer3DBAIAP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605475   
Orphanet
MedgenBAIAP2
Genetic Testing Registry BAIAP2
NextProtQ9UQB8 [Medical]
TSGene10458
GENETestsBAIAP2
Target ValidationBAIAP2
Huge Navigator BAIAP2 [HugePedia]
snp3D : Map Gene to Disease10458
BioCentury BCIQBAIAP2
ClinGenBAIAP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10458
Chemical/Pharm GKB GenePA25251
Clinical trialBAIAP2
Miscellaneous
canSAR (ICR)BAIAP2 (select the gene name)
Probes
Litterature
PubMed92 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBAIAP2
EVEXBAIAP2
GoPubMedBAIAP2
iHOPBAIAP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:25:14 CEST 2017

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