BATF2 (basic leucine zipper ATF-like transcription factor 2)

2011-02-01  

Identity

HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
SARI
FUSION GENES

Other Information

Locus ID:

NCBI: 116071
MIM: 614983
HGNC: 25163
Ensembl: ENSG00000168062

Variants:

dbSNP: 116071
ClinVar: 116071
TCGA: ENSG00000168062
COSMIC: BATF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168062ENST00000301887Q8N1L9
ENSG00000168062ENST00000435842Q8N1L9
ENSG00000168062ENST00000527716B4DV37
ENSG00000168062ENST00000534177E9PJ73

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
279268632016Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation.36
242822782014Novel mechanism of MDA-7/IL-24 cancer-specific apoptosis through SARI induction.20
205313012010Inhibition of AP-1 by SARI negatively regulates transformation progression mediated by CCN1.18
230497252012The function of SARI in modulating epithelial-mesenchymal transition and lung adenocarcinoma metastasis.14
204738972011Decreased expression of BATF2 is associated with a poor prognosis in hepatocellular carcinoma.11
257623442015BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs.11
242529322014Decreased expression of BATF2 is significantly associated with poor prognosis in oral tongue squamous cell carcinoma.10
263766152015Targeting Batf2 for infectious diseases and cancer.9
287397202017Inhibition of Bevacizumab-induced Epithelial-Mesenchymal Transition by BATF2 Overexpression Involves the Suppression of Wnt/β-Catenin Signaling in Glioblastoma Cells.7
218926282011Transcription suppression of SARI (suppressor of AP-1, regulated by IFN) by BCR-ABL in human leukemia cells.5

Citation

Dessen P

BATF2 (basic leucine zipper ATF-like transcription factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52085/batf2