Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

BBX (BBX, HMG-box containing)

Identity

Alias_namesbobby sox homolog (Drosophila)
Alias_symbol (synonym)MDS001
HSPC339
HBP2
Other aliasARTC1
HGNC (Hugo) BBX
LocusID (NCBI) 56987
Atlas_Id 60721
Location 3q13.12  [Link to chromosome band 3q13]
Location_base_pair Starts at 107522936 and ends at 107811329 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AXIN1 (16p13.3) / BBX (3q13.12)BBX (3q13.12) / BBX (3q13.12)BBX (3q13.12) / RB1 (13q14.2)
BBX (3q13.12) / SPARCL1 (4q22.1)IGF1R (15q26.3) / BBX (3q13.12)MIR548N (2q31.2) / BBX (3q13.12)
PRDM16 (1p36.32) / BBX (3q13.12)RUNX1T1 (8q21.3) / BBX (3q13.12)TMEM39A (3q13.33) / BBX (3q13.12)
TNFSF4 (1q25.1) / BBX (3q13.12)PRDM16 BBXTMEM39A BBX
AXIN1 BBX

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Breast: carcinoma with t(1;3)(p36;q13) PRDM16/BBX


External links

Nomenclature
HGNC (Hugo)BBX   14422
Cards
Entrez_Gene (NCBI)BBX  56987  BBX, HMG-box containing
AliasesARTC1; HBP2; HSPC339; MDS001
GeneCards (Weizmann)BBX
Ensembl hg19 (Hinxton)ENSG00000114439 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114439 [Gene_View]  chr3:107522936-107811329 [Contig_View]  BBX [Vega]
ICGC DataPortalENSG00000114439
TCGA cBioPortalBBX
AceView (NCBI)BBX
Genatlas (Paris)BBX
WikiGenes56987
SOURCE (Princeton)BBX
Genetics Home Reference (NIH)BBX
Genomic and cartography
GoldenPath hg38 (UCSC)BBX  -     chr3:107522936-107811329 +  3q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BBX  -     3q13.12   [Description]    (hg19-Feb_2009)
EnsemblBBX - 3q13.12 [CytoView hg19]  BBX - 3q13.12 [CytoView hg38]
Mapping of homologs : NCBIBBX [Mapview hg19]  BBX [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF052174 AF161457 AF168718 AF276948 AF276949
RefSeq transcript (Entrez)NM_001142568 NM_001276286 NM_020235
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BBX
Cluster EST : UnigeneHs.736885 [ NCBI ]
CGAP (NCI)Hs.736885
Alternative Splicing GalleryENSG00000114439
Gene ExpressionBBX [ NCBI-GEO ]   BBX [ EBI - ARRAY_EXPRESS ]   BBX [ SEEK ]   BBX [ MEM ]
Gene Expression Viewer (FireBrowse)BBX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56987
GTEX Portal (Tissue expression)BBX
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WY36   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WY36  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WY36
Splice isoforms : SwissVarQ8WY36
PhosPhoSitePlusQ8WY36
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)HMG_box_dom    TF_HMG_box_BBX_DUF2028   
Domain families : Pfam (Sanger)DUF2028 (PF09667)    HMG_box (PF00505)   
Domain families : Pfam (NCBI)pfam09667    pfam00505   
Domain families : Smart (EMBL)HMG (SM00398)  
Conserved Domain (NCBI)BBX
DMDM Disease mutations56987
Blocks (Seattle)BBX
SuperfamilyQ8WY36
Human Protein AtlasENSG00000114439
Peptide AtlasQ8WY36
HPRD10688
IPIIPI00300222   IPI00183699   IPI00442504   IPI00871518   IPI00877648   IPI00880126   IPI00877776   IPI00878379   IPI00878880   IPI00878732   IPI00879173   IPI00879012   IPI00879522   IPI00879370   IPI00879782   IPI00879637   IPI00880115   IPI00879964   IPI00880068   IPI00879905   IPI00877621   IPI00878383   
Protein Interaction databases
DIP (DOE-UCLA)Q8WY36
IntAct (EBI)Q8WY36
FunCoupENSG00000114439
BioGRIDBBX
STRING (EMBL)BBX
ZODIACBBX
Ontologies - Pathways
QuickGOQ8WY36
Ontology : AmiGODNA binding  nucleoplasm  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  bone development  
Ontology : EGO-EBIDNA binding  nucleoplasm  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  bone development  
NDEx NetworkBBX
Atlas of Cancer Signalling NetworkBBX
Wikipedia pathwaysBBX
Orthology - Evolution
OrthoDB56987
GeneTree (enSembl)ENSG00000114439
Phylogenetic Trees/Animal Genes : TreeFamBBX
HOVERGENQ8WY36
HOGENOMQ8WY36
Homologs : HomoloGeneBBX
Homology/Alignments : Family Browser (UCSC)BBX
Gene fusions - Rearrangements
Fusion: TCGAPRDM16 BBX
Fusion: TCGATMEM39A BBX
Fusion: TCGAAXIN1 BBX
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBBX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BBX
dbVarBBX
ClinVarBBX
1000_GenomesBBX 
Exome Variant ServerBBX
ExAC (Exome Aggregation Consortium)BBX (select the gene name)
Genetic variants : HAPMAP56987
Genomic Variants (DGV)BBX [DGVbeta]
DECIPHERBBX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBBX 
Mutations
ICGC Data PortalBBX 
TCGA Data PortalBBX 
Broad Tumor PortalBBX
OASIS PortalBBX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBBX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBBX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BBX
DgiDB (Drug Gene Interaction Database)BBX
DoCM (Curated mutations)BBX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BBX (select a term)
intoGenBBX
Cancer3DBBX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenBBX
Genetic Testing Registry BBX
NextProtQ8WY36 [Medical]
TSGene56987
GENETestsBBX
Target ValidationBBX
Huge Navigator BBX [HugePedia]
snp3D : Map Gene to Disease56987
BioCentury BCIQBBX
ClinGenBBX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56987
Chemical/Pharm GKB GenePA25280
Clinical trialBBX
Miscellaneous
canSAR (ICR)BBX (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBBX
EVEXBBX
GoPubMedBBX
iHOPBBX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:02:14 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.