BCAM (basal cell adhesion molecule (Lutheran blood group))

2007-02-01  

Identity

HGNC
LOCATION
19q13.32
LOCUSID
ALIAS
AU,CD239,LU,MSK19
FUSION GENES

Other Information

Locus ID:

NCBI: 4059
MIM: 612773
HGNC: 6722
Ensembl: ENSG00000187244

Variants:

dbSNP: 4059
ClinVar: 4059
TCGA: ENSG00000187244
COSMIC: BCAM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187244ENST00000270233P50895
ENSG00000187244ENST00000590196K7ERB7
ENSG00000187244ENST00000591520K7ENU8
ENSG00000187244ENST00000611077A0A087WXM8

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203709132010Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data.35
122440662002Identification of the binding site for the Lutheran blood group glycoprotein on laminin alpha 5 through expression of chimeric laminin chains in vivo.23
205623142010Aggregation of mononuclear and red blood cells through an {alpha}4{beta}1-Lu/basal cell adhesion molecule interaction in sickle cell disease.16
186351662008Laminin alpha 5 mediates ectopic adhesion of hepatocellular carcinoma through integrins and/or Lutheran/basal cell adhesion molecule.15
176388542007The Laminin 511/521-binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3.12
246160942014Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation.12
271436912016BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer.12
224049362012Epinephrine modulates BCAM/Lu and ICAM-4 expression on the sickle cell trait red blood cell membrane.11
244539762014Lu/BCAM adhesion glycoprotein is a receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1).11
165844462006The Lutheran glycoprotein: a multifunctional adhesion receptor.10

Citation

Dessen P

BCAM (basal cell adhesion molecule (Lutheran blood group))

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43679/bcam