BCAP31 (B cell receptor associated protein 31)

2008-08-01  

Identity

HGNC
BCAP31
LOCATION
Xq28
LOCUSID
10134
ALIAS
6C6-AG,BAP31,CDM,DDCH,DXS1357E
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10134
MIM: 300398
HGNC: 16695
Ensembl: ENSG00000185825

Variants:

dbSNP: 10134
ClinVar: 10134
TCGA: ENSG00000185825
COSMIC: BCAP31

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185825ENST00000345046P51572
ENSG00000185825ENST00000416815C9JSP1
ENSG00000185825ENST00000423827C9JMD7
ENSG00000185825ENST00000429550C9JQ75
ENSG00000185825ENST00000430088C9JM14
ENSG00000185825ENST00000442093C9J0M4
ENSG00000185825ENST00000458587P51572
ENSG00000185825ENST00000645377A0A2R8Y5M6
ENSG00000185825ENST00000647529P51572

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Programmed Cell DeathREACTOMER-HSA-5357801
ApoptosisREACTOMER-HSA-109581
Apoptotic execution phaseREACTOMER-HSA-75153
Apoptotic cleavage of cellular proteinsREACTOMER-HSA-111465

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383487182024NDC1 promotes hepatocellular carcinoma tumorigenesis by targeting BCAP31 to activate PI3K/AKT signaling.2
384741952024BAP31 Promotes Angiogenesis via Galectin-3 Upregulation in Neuroblastoma.0
387911412024p20BAP31 Induces Autophagy in Colorectal Cancer Cells by Promoting PERK-Mediated ER Stress.1
383487182024NDC1 promotes hepatocellular carcinoma tumorigenesis by targeting BCAP31 to activate PI3K/AKT signaling.2
384741952024BAP31 Promotes Angiogenesis via Galectin-3 Upregulation in Neuroblastoma.0
387911412024p20BAP31 Induces Autophagy in Colorectal Cancer Cells by Promoting PERK-Mediated ER Stress.1
372961052023HNF4A-BAP31-VDAC1 axis synchronously regulates cell proliferation and ferroptosis in gastric cancer.3
380690612023BAP31-Mediated miR-206/133b Cluster Promotes Transendothelial Migration and Metastasis of Colorectal Cancer.2
372961052023HNF4A-BAP31-VDAC1 axis synchronously regulates cell proliferation and ferroptosis in gastric cancer.3
380690612023BAP31-Mediated miR-206/133b Cluster Promotes Transendothelial Migration and Metastasis of Colorectal Cancer.2
334394102021Biological roles of the B cell receptor-associated protein 31: Functional Implication in Cancer.4
336031602021Further delineation of BCAP31-linked intellectual disability: description of 17 new families with LoF and missense variants.5
339305072021BAP31: Physiological functions and roles in disease.19
334394102021Biological roles of the B cell receptor-associated protein 31: Functional Implication in Cancer.4
336031602021Further delineation of BCAP31-linked intellectual disability: description of 17 new families with LoF and missense variants.5

Citation

Dessen P

BCAP31 (B cell receptor associated protein 31)

Atlas Genet Cytogenet Oncol Haematol. 2008-08-01

Online version: http://atlasgeneticsoncology.org/gene/50285/bcap31