Atlas of Genetics and Cytogenetics in Oncology and Haematology


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BCAT2 (branched chain amino acid transaminase 2)

Identity

Other aliasBCAM
BCATM
BCT2
PP18
HGNC (Hugo) BCAT2
LocusID (NCBI) 587
Atlas_Id 56927
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 48795062 and ends at 48811063 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BCAT2 (19q13.33) / IRF3 (19q13.33)BCAT2 (19q13.33) / MS4A6A (11q12.2)BCAT2 (19q13.33) / ZNF76 (6p21.31)
USP34 (2p15) / BCAT2 (19q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BCAT2   977
Cards
Entrez_Gene (NCBI)BCAT2  587  branched chain amino acid transaminase 2
AliasesBCAM; BCATM; BCT2; PP18
GeneCards (Weizmann)BCAT2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr19:48795062-48811063 [Contig_View]  BCAT2 [Vega]
TCGA cBioPortalBCAT2
AceView (NCBI)BCAT2
Genatlas (Paris)BCAT2
WikiGenes587
SOURCE (Princeton)BCAT2
Genetics Home Reference (NIH)BCAT2
Genomic and cartography
GoldenPath hg38 (UCSC)BCAT2  -     chr19:48795062-48811063 -  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BCAT2  -     19q13.33   [Description]    (hg19-Feb_2009)
EnsemblBCAT2 - 19q13.33 [CytoView hg19]  BCAT2 - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBIBCAT2 [Mapview hg19]  BCAT2 [Mapview hg38]
OMIM113530   
Gene and transcription
Genbank (Entrez)AF268047 AF268048 AK023909 AK093627 AK223522
RefSeq transcript (Entrez)NM_001164773 NM_001190 NM_001284325
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BCAT2
Cluster EST : UnigeneHs.512670 [ NCBI ]
CGAP (NCI)Hs.512670
Gene ExpressionBCAT2 [ NCBI-GEO ]   BCAT2 [ EBI - ARRAY_EXPRESS ]   BCAT2 [ SEEK ]   BCAT2 [ MEM ]
Gene Expression Viewer (FireBrowse)BCAT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)587
GTEX Portal (Tissue expression)BCAT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15382   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15382  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15382
Splice isoforms : SwissVarO15382
Catalytic activity : Enzyme2.6.1.42 [ Enzyme-Expasy ]   2.6.1.422.6.1.42 [ IntEnz-EBI ]   2.6.1.42 [ BRENDA ]   2.6.1.42 [ KEGG ]   
PhosPhoSitePlusO15382
Domaine pattern : Prosite (Expaxy)AA_TRANSFER_CLASS_4 (PS00770)   
Domains : Interpro (EBI)Aminotrans_IV    Aminotrans_IV_CS    B_amino_transII    BCAT_family   
Domain families : Pfam (Sanger)Aminotran_4 (PF01063)   
Domain families : Pfam (NCBI)pfam01063   
Conserved Domain (NCBI)BCAT2
DMDM Disease mutations587
Blocks (Seattle)BCAT2
PDB (SRS)1EKF    1EKP    1EKV    1KT8    1KTA    2A1H    2HDK    2HG8    2HGW    2HGX    2HHF    5BWR    5BWT    5BWU    5BWV    5BWW    5BWX    5CR5    5HNE    5I5S    5I5T    5I5U    5I5V    5I5W    5I5X    5I5Y    5I60   
PDB (PDBSum)1EKF    1EKP    1EKV    1KT8    1KTA    2A1H    2HDK    2HG8    2HGW    2HGX    2HHF    5BWR    5BWT    5BWU    5BWV    5BWW    5BWX    5CR5    5HNE    5I5S    5I5T    5I5U    5I5V    5I5W    5I5X    5I5Y    5I60   
PDB (IMB)1EKF    1EKP    1EKV    1KT8    1KTA    2A1H    2HDK    2HG8    2HGW    2HGX    2HHF    5BWR    5BWT    5BWU    5BWV    5BWW    5BWX    5CR5    5HNE    5I5S    5I5T    5I5U    5I5V    5I5W    5I5X    5I5Y    5I60   
PDB (RSDB)1EKF    1EKP    1EKV    1KT8    1KTA    2A1H    2HDK    2HG8    2HGW    2HGX    2HHF    5BWR    5BWT    5BWU    5BWV    5BWW    5BWX    5CR5    5HNE    5I5S    5I5T    5I5U    5I5V    5I5W    5I5X    5I5Y    5I60   
Structural Biology KnowledgeBase1EKF    1EKP    1EKV    1KT8    1KTA    2A1H    2HDK    2HG8    2HGW    2HGX    2HHF    5BWR    5BWT    5BWU    5BWV    5BWW    5BWX    5CR5    5HNE    5I5S    5I5T    5I5U    5I5V    5I5W    5I5X    5I5Y    5I60   
SCOP (Structural Classification of Proteins)1EKF    1EKP    1EKV    1KT8    1KTA    2A1H    2HDK    2HG8    2HGW    2HGX    2HHF    5BWR    5BWT    5BWU    5BWV    5BWW    5BWX    5CR5    5HNE    5I5S    5I5T    5I5U    5I5V    5I5W    5I5X    5I5Y    5I60   
CATH (Classification of proteins structures)1EKF    1EKP    1EKV    1KT8    1KTA    2A1H    2HDK    2HG8    2HGW    2HGX    2HHF    5BWR    5BWT    5BWU    5BWV    5BWW    5BWX    5CR5    5HNE    5I5S    5I5T    5I5U    5I5V    5I5W    5I5X    5I5Y    5I60   
SuperfamilyO15382
Peptide AtlasO15382
IPIIPI00396258   IPI01009966   IPI00181135   
Protein Interaction databases
DIP (DOE-UCLA)O15382
IntAct (EBI)O15382
BioGRIDBCAT2
STRING (EMBL)BCAT2
ZODIACBCAT2
Ontologies - Pathways
QuickGOO15382
Ontology : AmiGObranched-chain-amino-acid transaminase activity  branched-chain-amino-acid transaminase activity  mitochondrion  mitochondrial matrix  isoleucine catabolic process  branched-chain amino acid biosynthetic process  branched-chain amino acid catabolic process  leucine biosynthetic process  valine biosynthetic process  regulation of hormone levels  L-leucine transaminase activity  L-valine transaminase activity  L-isoleucine transaminase activity  cellular response to leukemia inhibitory factor  
Ontology : EGO-EBIbranched-chain-amino-acid transaminase activity  branched-chain-amino-acid transaminase activity  mitochondrion  mitochondrial matrix  isoleucine catabolic process  branched-chain amino acid biosynthetic process  branched-chain amino acid catabolic process  leucine biosynthetic process  valine biosynthetic process  regulation of hormone levels  L-leucine transaminase activity  L-valine transaminase activity  L-isoleucine transaminase activity  cellular response to leukemia inhibitory factor  
Pathways : KEGGValine, leucine and isoleucine degradation    Valine, leucine and isoleucine biosynthesis    Pantothenate and CoA biosynthesis   
NDEx NetworkBCAT2
Atlas of Cancer Signalling NetworkBCAT2
Wikipedia pathwaysBCAT2
Orthology - Evolution
OrthoDB587
Phylogenetic Trees/Animal Genes : TreeFamBCAT2
HOVERGENO15382
HOGENOMO15382
Homologs : HomoloGeneBCAT2
Homology/Alignments : Family Browser (UCSC)BCAT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBCAT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BCAT2
dbVarBCAT2
ClinVarBCAT2
1000_GenomesBCAT2 
Exome Variant ServerBCAT2
ExAC (Exome Aggregation Consortium)BCAT2 (select the gene name)
Genetic variants : HAPMAP587
Genomic Variants (DGV)BCAT2 [DGVbeta]
DECIPHERBCAT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBCAT2 
Mutations
ICGC Data PortalBCAT2 
TCGA Data PortalBCAT2 
Broad Tumor PortalBCAT2
OASIS PortalBCAT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBCAT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBCAT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BCAT2
DgiDB (Drug Gene Interaction Database)BCAT2
DoCM (Curated mutations)BCAT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BCAT2 (select a term)
intoGenBCAT2
Cancer3DBCAT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM113530   
Orphanet
MedgenBCAT2
Genetic Testing Registry BCAT2
NextProtO15382 [Medical]
TSGene587
GENETestsBCAT2
Target ValidationBCAT2
Huge Navigator BCAT2 [HugePedia]
snp3D : Map Gene to Disease587
BioCentury BCIQBCAT2
ClinGenBCAT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD587
Chemical/Pharm GKB GenePA25289
Clinical trialBCAT2
Miscellaneous
canSAR (ICR)BCAT2 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBCAT2
EVEXBCAT2
GoPubMedBCAT2
iHOPBCAT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:47:50 CEST 2017

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