BCDIN3D (BCDIN3 domain containing RNA methyltransferase)

2013-01-01  

Identity

HGNC
BCDIN3D
LOCATION
12q13.12
LOCUSID
144233
ALIAS
-

Other Information

Locus ID:

NCBI: 144233
HGNC: 27050
Ensembl: ENSG00000186666

Variants:

dbSNP: 144233
ClinVar: 144233
TCGA: ENSG00000186666
COSMIC: BCDIN3D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186666ENST00000333924Q7Z5W3

Expression (GTEx)

0
1
2
3
4
5
6
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
230631212012Human RNA methyltransferase BCDIN3D regulates microRNA processing.52
207245812010Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies.47
202153972010Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.44
208161952010Analyses of shared genetic factors between asthma and obesity in children.43
207129032010Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.18
281194162017Human BCDIN3D monomethylates cytoplasmic histidine transfer RNA.9
281194162017Human BCDIN3D monomethylates cytoplasmic histidine transfer RNA.9
272599932016Elevated expression of RNA methyltransferase BCDIN3D predicts poor prognosis in breast cancer.8
313295842019BCDIN3D regulates tRNAHis 3' fragment processing.1
319195122020Crystal structure of human cytoplasmic tRNAHis-specific 5'-monomethylphosphate capping enzyme.0

Citation

Dessen P

BCDIN3D (BCDIN3 domain containing RNA methyltransferase)

Atlas Genet Cytogenet Oncol Haematol. 2013-01-01

Online version: http://atlasgeneticsoncology.org/gene/53123/bcdin3d