Atlas of Genetics and Cytogenetics in Oncology and Haematology


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BCL2L10 (BCL2-like 10 (apoptosis facilitator))

Identity

Other namesBCL-B
Boo
Diva
HGNC (Hugo) BCL2L10
LocusID (NCBI) 10017
Location 15q21.2
Location_base_pair Starts at 52401822 and ends at 52404972 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)BCL2L10   993
Cards
Entrez_Gene (NCBI)BCL2L10  10017  BCL2-like 10 (apoptosis facilitator)
GeneCards (Weizmann)BCL2L10
Ensembl (Hinxton)ENSG00000137875 [Gene_View]  chr15:52401822-52404972 [Contig_View]  BCL2L10 [Vega]
ICGC DataPortalENSG00000137875
cBioPortalBCL2L10
AceView (NCBI)BCL2L10
Genatlas (Paris)BCL2L10
WikiGenes10017
SOURCE (Princeton)NM_020396
Genomic and cartography
GoldenPath (UCSC)BCL2L10  -  15q21.2   chr15:52401822-52404972 -  15q21.2   [Description]    (hg19-Feb_2009)
EnsemblBCL2L10 - 15q21.2 [CytoView]
Mapping of homologs : NCBIBCL2L10 [Mapview]
OMIM606910   
Gene and transcription
Genbank (Entrez)AF285092 AF326964 BC093826 BC093828 BC104442
RefSeq transcript (Entrez)NM_020396
RefSeq genomic (Entrez)AC_000147 NC_000015 NC_018926 NT_010194 NW_001838218 NW_004929398
Consensus coding sequences : CCDS (NCBI)BCL2L10
Cluster EST : UnigeneHs.283672 [ NCBI ]
CGAP (NCI)Hs.283672
Alternative Splicing : Fast-db (Paris)GSHG0010423
Alternative Splicing GalleryENSG00000137875
Gene ExpressionBCL2L10 [ NCBI-GEO ]     BCL2L10 [ SEEK ]   BCL2L10 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HD36 (Uniprot)
NextProtQ9HD36  [Medical]
With graphics : InterProQ9HD36
Splice isoforms : SwissVarQ9HD36 (Swissvar)
Domaine pattern : Prosite (Expaxy)BCL2_FAMILY (PS50062)    BH1 (PS01080)    BH2 (PS01258)   
Domains : Interpro (EBI)Bcl2-like [organisation]   Bcl2_BH1_motif_CS [organisation]   Bcl2_BH2_motif_CS [organisation]   Blc2_fam [organisation]  
Related proteins : CluSTrQ9HD36
Domain families : Pfam (Sanger)Bcl-2 (PF00452)   
Domain families : Pfam (NCBI)pfam00452   
DMDM Disease mutations10017
Blocks (Seattle)Q9HD36
PDB (SRS)4B4S   
PDB (PDBSum)4B4S   
PDB (IMB)4B4S   
PDB (RSDB)4B4S   
Human Protein AtlasENSG00000137875 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9HD36
HPRD06071
IPIIPI00216614   
Protein Interaction databases
DIP (DOE-UCLA)Q9HD36
IntAct (EBI)Q9HD36
FunCoupENSG00000137875
BioGRIDBCL2L10
InParanoidQ9HD36
Interologous Interaction database Q9HD36
IntegromeDBBCL2L10
STRING (EMBL)BCL2L10
Ontologies - Pathways
Ontology : AmiGOprotein binding  mitochondrion  mitochondrial outer membrane  cytosol  activation of cysteine-type endopeptidase activity involved in apoptotic process  spermatogenesis  female gamete generation  intrinsic apoptotic signaling pathway in response to DNA damage  membrane  integral component of membrane  nuclear membrane  protein homodimerization activity  positive regulation of apoptotic process  negative regulation of apoptotic process  protein heterodimerization activity  extrinsic apoptotic signaling pathway in absence of ligand  negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  negative regulation of intrinsic apoptotic signaling pathway  
Ontology : EGO-EBIprotein binding  mitochondrion  mitochondrial outer membrane  cytosol  activation of cysteine-type endopeptidase activity involved in apoptotic process  spermatogenesis  female gamete generation  intrinsic apoptotic signaling pathway in response to DNA damage  membrane  integral component of membrane  nuclear membrane  protein homodimerization activity  positive regulation of apoptotic process  negative regulation of apoptotic process  protein heterodimerization activity  extrinsic apoptotic signaling pathway in absence of ligand  negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  negative regulation of intrinsic apoptotic signaling pathway  
Protein Interaction DatabaseBCL2L10
Wikipedia pathwaysBCL2L10
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)BCL2L10
snp3D : Map Gene to Disease10017
SNP (GeneSNP Utah)BCL2L10
SNP : HGBaseBCL2L10
Genetic variants : HAPMAPBCL2L10
Exome VariantBCL2L10
1000_GenomesBCL2L10 
ICGC programENSG00000137875 
Somatic Mutations in Cancer : COSMICBCL2L10 
CONAN: Copy Number AnalysisBCL2L10 
Mutations and Diseases : HGMDBCL2L10
Mutations and Diseases : intOGenBCL2L10
Genomic VariantsBCL2L10  BCL2L10 [DGVbeta]
dbVarBCL2L10
ClinVarBCL2L10
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM606910   
MedgenBCL2L10
GENETestsBCL2L10
Disease Genetic AssociationBCL2L10
Huge Navigator BCL2L10 [HugePedia]  BCL2L10 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneBCL2L10
Homology/Alignments : Family Browser (UCSC)BCL2L10
Phylogenetic Trees/Animal Genes : TreeFamBCL2L10
Chemical/Protein Interactions : CTD10017
Chemical/Pharm GKB GenePA25304
Clinical trialBCL2L10
Cancer Resource (Charite)ENSG00000137875
Other databases
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
CoreMineBCL2L10
iHOPBCL2L10
OncoSearchBCL2L10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:39:35 CEST 2014

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