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BCL2L10 (BCL2 like 10)

Identity

Alias_namesBCL2-like 10 (apoptosis facilitator)
Alias_symbol (synonym)Diva
Boo
BCL-B
HGNC (Hugo) BCL2L10
LocusID (NCBI) 10017
Atlas_Id 771
Location 15q21.2  [Link to chromosome band 15q21]
Location_base_pair Starts at 52401466 and ends at 52404972 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BCL2L10   993
Cards
Entrez_Gene (NCBI)BCL2L10  10017  BCL2 like 10
AliasesBCL-B; Boo; Diva; bcl2-L-10
GeneCards (Weizmann)BCL2L10
Ensembl hg19 (Hinxton)ENSG00000137875 [Gene_View]  chr15:52401466-52404972 [Contig_View]  BCL2L10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000137875 [Gene_View]  chr15:52401466-52404972 [Contig_View]  BCL2L10 [Vega]
ICGC DataPortalENSG00000137875
TCGA cBioPortalBCL2L10
AceView (NCBI)BCL2L10
Genatlas (Paris)BCL2L10
WikiGenes10017
SOURCE (Princeton)BCL2L10
Genetics Home Reference (NIH)BCL2L10
Genomic and cartography
GoldenPath hg19 (UCSC)BCL2L10  -     chr15:52401466-52404972 -  15q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)BCL2L10  -     15q21.2   [Description]    (hg38-Dec_2013)
EnsemblBCL2L10 - 15q21.2 [CytoView hg19]  BCL2L10 - 15q21.2 [CytoView hg38]
Mapping of homologs : NCBIBCL2L10 [Mapview hg19]  BCL2L10 [Mapview hg38]
OMIM606910   
Gene and transcription
Genbank (Entrez)AF285092 AF326964 BC093826 BC093828 BC104442
RefSeq transcript (Entrez)NM_001306168 NM_020396
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)BCL2L10
Cluster EST : UnigeneHs.283672 [ NCBI ]
CGAP (NCI)Hs.283672
Alternative Splicing GalleryENSG00000137875
Gene ExpressionBCL2L10 [ NCBI-GEO ]   BCL2L10 [ EBI - ARRAY_EXPRESS ]   BCL2L10 [ SEEK ]   BCL2L10 [ MEM ]
Gene Expression Viewer (FireBrowse)BCL2L10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10017
GTEX Portal (Tissue expression)BCL2L10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HD36   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HD36  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HD36
Splice isoforms : SwissVarQ9HD36
PhosPhoSitePlusQ9HD36
Domaine pattern : Prosite (Expaxy)BCL2_FAMILY (PS50062)    BH1 (PS01080)    BH2 (PS01258)   
Domains : Interpro (EBI)Bcl2-like    Bcl2_BH1_motif_CS    Bcl2_BH2_motif_CS    Blc2_fam   
Domain families : Pfam (Sanger)Bcl-2 (PF00452)   
Domain families : Pfam (NCBI)pfam00452   
Conserved Domain (NCBI)BCL2L10
DMDM Disease mutations10017
Blocks (Seattle)BCL2L10
PDB (SRS)4B4S   
PDB (PDBSum)4B4S   
PDB (IMB)4B4S   
PDB (RSDB)4B4S   
Structural Biology KnowledgeBase4B4S   
SCOP (Structural Classification of Proteins)4B4S   
CATH (Classification of proteins structures)4B4S   
SuperfamilyQ9HD36
Human Protein AtlasENSG00000137875
Peptide AtlasQ9HD36
HPRD06071
IPIIPI00216614   
Protein Interaction databases
DIP (DOE-UCLA)Q9HD36
IntAct (EBI)Q9HD36
FunCoupENSG00000137875
BioGRIDBCL2L10
STRING (EMBL)BCL2L10
ZODIACBCL2L10
Ontologies - Pathways
QuickGOQ9HD36
Ontology : AmiGOprotein binding  mitochondrion  mitochondrial outer membrane  cytosol  activation of cysteine-type endopeptidase activity involved in apoptotic process  spermatogenesis  female gamete generation  intrinsic apoptotic signaling pathway in response to DNA damage  membrane  integral component of membrane  nuclear membrane  protein homodimerization activity  negative regulation of apoptotic process  protein heterodimerization activity  extrinsic apoptotic signaling pathway in absence of ligand  negative regulation of intrinsic apoptotic signaling pathway  
Ontology : EGO-EBIprotein binding  mitochondrion  mitochondrial outer membrane  cytosol  activation of cysteine-type endopeptidase activity involved in apoptotic process  spermatogenesis  female gamete generation  intrinsic apoptotic signaling pathway in response to DNA damage  membrane  integral component of membrane  nuclear membrane  protein homodimerization activity  negative regulation of apoptotic process  protein heterodimerization activity  extrinsic apoptotic signaling pathway in absence of ligand  negative regulation of intrinsic apoptotic signaling pathway  
NDEx NetworkBCL2L10
Atlas of Cancer Signalling NetworkBCL2L10
Wikipedia pathwaysBCL2L10
Orthology - Evolution
OrthoDB10017
GeneTree (enSembl)ENSG00000137875
Phylogenetic Trees/Animal Genes : TreeFamBCL2L10
HOVERGENQ9HD36
HOGENOMQ9HD36
Homologs : HomoloGeneBCL2L10
Homology/Alignments : Family Browser (UCSC)BCL2L10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBCL2L10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BCL2L10
dbVarBCL2L10
ClinVarBCL2L10
1000_GenomesBCL2L10 
Exome Variant ServerBCL2L10
ExAC (Exome Aggregation Consortium)BCL2L10 (select the gene name)
Genetic variants : HAPMAP10017
Genomic Variants (DGV)BCL2L10 [DGVbeta]
DECIPHER (Syndromes)15:52401466-52404972  ENSG00000137875
CONAN: Copy Number AnalysisBCL2L10 
Mutations
ICGC Data PortalBCL2L10 
TCGA Data PortalBCL2L10 
Broad Tumor PortalBCL2L10
OASIS PortalBCL2L10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBCL2L10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBCL2L10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BCL2L10
DgiDB (Drug Gene Interaction Database)BCL2L10
DoCM (Curated mutations)BCL2L10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BCL2L10 (select a term)
intoGenBCL2L10
Cancer3DBCL2L10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606910   
Orphanet
MedgenBCL2L10
Genetic Testing Registry BCL2L10
NextProtQ9HD36 [Medical]
TSGene10017
GENETestsBCL2L10
Huge Navigator BCL2L10 [HugePedia]
snp3D : Map Gene to Disease10017
BioCentury BCIQBCL2L10
ClinGenBCL2L10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10017
Chemical/Pharm GKB GenePA25304
Clinical trialBCL2L10
Miscellaneous
canSAR (ICR)BCL2L10 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBCL2L10
EVEXBCL2L10
GoPubMedBCL2L10
iHOPBCL2L10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Nov 18 19:32:04 CET 2016

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