Identity
HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
BCL-W,BCL2-L-2,BCLW,PPP1R51
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 599
MIM: 601931
HGNC: 995
Ensembl: ENSG00000129473
Variants:
dbSNP: 599
ClinVar: 599
TCGA: ENSG00000129473
COSMIC: BCL2L2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| MicroRNAs in cancer | KEGG | hsa05206 |
| MicroRNAs in cancer | KEGG | ko05206 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36441929 | 2023 | MiR-140 promotes the progression of intracranial aneurysms by targeting BCL2L2. | 3 |
| 37567974 | 2023 | BCL-W makes only minor contributions to MYC-driven lymphoma development. | 0 |
| 36441929 | 2023 | MiR-140 promotes the progression of intracranial aneurysms by targeting BCL2L2. | 3 |
| 37567974 | 2023 | BCL-W makes only minor contributions to MYC-driven lymphoma development. | 0 |
| 35894779 | 2022 | Novel read-through fusion transcript Bcl2l2-Pabpn1 in glioblastoma cells. | 5 |
| 35894779 | 2022 | Novel read-through fusion transcript Bcl2l2-Pabpn1 in glioblastoma cells. | 5 |
| 33744257 | 2021 | Long non-coding RNA KCNQ1OT1 promotes hydrogen peroxide-induced lens epithelial cell apoptosis and oxidative stress by regulating miR-223-3p/BCL2L2 axis. | 1 |
| 33784008 | 2021 | BCL2L2 loss renders -14q renal cancer dependent on BCL2L1 that mediates resistance to tyrosine kinase inhibitors. | 3 |
| 33974236 | 2021 | MT1JP-mediated miR-24-3p/BCL2L2 axis promotes Lenvatinib resistance in hepatocellular carcinoma cells by inhibiting apoptosis. | 25 |
| 34531377 | 2021 | BCL-W expression associates with poor outcome in patients with peripheral T-cell lymphoma not otherwise specified. | 2 |
| 34620126 | 2021 | Knockdown of circ_0011946 targets miR-216a-5p/BCL2L2 axis to regulate proliferation, migration, invasion and apoptosis of oral squamous cell carcinoma cells. | 3 |
| 33744257 | 2021 | Long non-coding RNA KCNQ1OT1 promotes hydrogen peroxide-induced lens epithelial cell apoptosis and oxidative stress by regulating miR-223-3p/BCL2L2 axis. | 1 |
| 33784008 | 2021 | BCL2L2 loss renders -14q renal cancer dependent on BCL2L1 that mediates resistance to tyrosine kinase inhibitors. | 3 |
| 33974236 | 2021 | MT1JP-mediated miR-24-3p/BCL2L2 axis promotes Lenvatinib resistance in hepatocellular carcinoma cells by inhibiting apoptosis. | 25 |
| 34531377 | 2021 | BCL-W expression associates with poor outcome in patients with peripheral T-cell lymphoma not otherwise specified. | 2 |
Citation
Dessen P
BCL2L2 (BCL2 like 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/775/bcl2l2
