BCL6B (BCL6B transcription repressor)

2003-06-01  

Identity

HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
BAZF,ZBTB28,ZNF62

Other Information

Locus ID:

NCBI: 255877
MIM: 608992
HGNC: 1002
Ensembl: ENSG00000161940

Variants:

dbSNP: 255877
ClinVar: 255877
TCGA: ENSG00000161940
COSMIC: BCL6B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161940ENST00000293805Q8N143
ENSG00000161940ENST00000537931H0YGW0
ENSG00000161940ENST00000573503I3L396
ENSG00000161940ENST00000576705I3L304

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
259091682015Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU.17
219176502012Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival.0
241917142013Promoter hypermethylation of BCL6B gene is a potential plasma DNA biomarker for gastric cancer.0
250082342014The survival decrease in gastric cancer is associated with the methylation of B-cell CLL/lymphoma 6 member B promoter.0
252183452014B cell CLL/lymphoma 6 member B inhibits hepatocellular carcinoma metastases in vitro and in mice.0
259707802015BCL6B expression in hepatocellular carcinoma and its efficacy in the inhibition of liver damage and fibrogenesis.0
293933772018BCL6B suppresses proliferation and migration of colorectal carcinoma cells through inhibition of the PI3K/AKT signaling pathway.0

Citation

Dessen P

BCL6B (BCL6B transcription repressor)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/777/bcl6b