Atlas of Genetics and Cytogenetics in Oncology and Haematology

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BCL7A (BAF chromatin remodeling complex subunit BCL7A)

Identity

Alias (NCBI)BCL7
HGNC (Hugo) BCL7A
HGNC Previous nameBCL7
HGNC Previous nameB-cell CLL/lymphoma 7A
 BCL tumor suppressor 7A
 BCL7A, BAF complex component
LocusID (NCBI) 605
Atlas_Id 778
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 122021884 and ends at 122062044 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCL7A (12q24.31) / BCL7A (12q24.31)BCL7A (12q24.31) / KCNIP3 (2q11.1)BCL7A (12q24.31) / MYC (8q24.21)
Ig () / BCL7A (12q24.31)MYC (8q24.21) / BCL7A (12q24.31)PGBD2 (1q44) / BCL7A (12q24.31)
S100A6 (1q21.3) / BCL7A (12q24.31)BCL7A 12q24.31 / KCNIP3 2q11.1S100A6 1q21.3 / BCL7A 12q24.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(12;19)(q24;p13) BCL7A/DAZAP1

External links

Nomenclature
HGNC (Hugo)BCL7A   1004
Cards
Entrez_Gene (NCBI)BCL7A    BAF chromatin remodeling complex subunit BCL7A
AliasesBCL7
GeneCards (Weizmann)BCL7A
Ensembl hg19 (Hinxton)ENSG00000110987 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110987 [Gene_View]  ENSG00000110987 [Sequence]  chr12:122021884-122062044 [Contig_View]  BCL7A [Vega]
ICGC DataPortalENSG00000110987
TCGA cBioPortalBCL7A
AceView (NCBI)BCL7A
Genatlas (Paris)BCL7A
SOURCE (Princeton)BCL7A
Genetics Home Reference (NIH)BCL7A
Genomic and cartography
GoldenPath hg38 (UCSC)BCL7A  -     chr12:122021884-122062044 +  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BCL7A  -     12q24.31   [Description]    (hg19-Feb_2009)
GoldenPathBCL7A - 12q24.31 [CytoView hg19]  BCL7A - 12q24.31 [CytoView hg38]
ImmunoBaseENSG00000110987
genome Data Viewer NCBIBCL7A [Mapview hg19]  
OMIM601406   
Gene and transcription
Genbank (Entrez)AK296159 AK316486 BC094723 BC113627 BM801030
RefSeq transcript (Entrez)NM_001024808 NM_020993
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BCL7A
Alternative Splicing GalleryENSG00000110987
Gene ExpressionBCL7A [ NCBI-GEO ]   BCL7A [ EBI - ARRAY_EXPRESS ]   BCL7A [ SEEK ]   BCL7A [ MEM ]
Gene Expression Viewer (FireBrowse)BCL7A [ Firebrowse - Broad ]
GenevisibleExpression of BCL7A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)605
GTEX Portal (Tissue expression)BCL7A
Human Protein AtlasENSG00000110987-BCL7A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ4VC05   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ4VC05  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ4VC05
Splice isoforms : SwissVarQ4VC05
PhosPhoSitePlusQ4VC05
Domains : Interpro (EBI)BCL7   
Domain families : Pfam (Sanger)BCL_N (PF04714)   
Domain families : Pfam (NCBI)pfam04714   
Conserved Domain (NCBI)BCL7A
Blocks (Seattle)BCL7A
SuperfamilyQ4VC05
Human Protein Atlas [tissue]ENSG00000110987-BCL7A [tissue]
Peptide AtlasQ4VC05
HPRD03243
IPIIPI00607700   IPI00025786   
Protein Interaction databases
DIP (DOE-UCLA)Q4VC05
IntAct (EBI)Q4VC05
BioGRIDBCL7A
STRING (EMBL)BCL7A
ZODIACBCL7A
Ontologies - Pathways
QuickGOQ4VC05
Ontology : AmiGOmolecular_function  protein binding  cellular_component  negative regulation of transcription, DNA-templated  
Ontology : EGO-EBImolecular_function  protein binding  cellular_component  negative regulation of transcription, DNA-templated  
NDEx NetworkBCL7A
Atlas of Cancer Signalling NetworkBCL7A
Wikipedia pathwaysBCL7A
Orthology - Evolution
OrthoDB605
GeneTree (enSembl)ENSG00000110987
Phylogenetic Trees/Animal Genes : TreeFamBCL7A
HOGENOMQ4VC05
Homologs : HomoloGeneBCL7A
Homology/Alignments : Family Browser (UCSC)BCL7A
Gene fusions - Rearrangements
Fusion : MitelmanBCL7A/KCNIP3 [12q24.31/2q11.1]  
Fusion : MitelmanMYC/BCL7A [8q24.21/12q24.31]  
Fusion : MitelmanS100A6/BCL7A [1q21.3/12q24.31]  
Fusion PortalBCL7A 12q24.31 KCNIP3 2q11.1 BRCA
Fusion PortalS100A6 1q21.3 BCL7A 12q24.31 THCA
Fusion : QuiverBCL7A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBCL7A [hg38]
dbVarBCL7A
ClinVarBCL7A
MonarchBCL7A
1000_GenomesBCL7A 
Exome Variant ServerBCL7A
GNOMAD BrowserENSG00000110987
Varsome BrowserBCL7A
Genomic Variants (DGV)BCL7A [DGVbeta]
DECIPHERBCL7A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBCL7A 
Mutations
ICGC Data PortalBCL7A 
TCGA Data PortalBCL7A 
Broad Tumor PortalBCL7A
OASIS PortalBCL7A [ Somatic mutations - Copy number]
Cancer Gene: CensusBCL7A 
Somatic Mutations in Cancer : COSMICBCL7A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DBCL7A
Mutations and Diseases : HGMDBCL7A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BCL7A
DgiDB (Drug Gene Interaction Database)BCL7A
DoCM (Curated mutations)BCL7A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BCL7A (select a term)
intoGenBCL7A
Cancer3DBCL7A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601406   
Orphanet
DisGeNETBCL7A
MedgenBCL7A
Genetic Testing Registry BCL7A
NextProtQ4VC05 [Medical]
GENETestsBCL7A
Target ValidationBCL7A
Huge Navigator BCL7A [HugePedia]
ClinGenBCL7A
Clinical trials, drugs, therapy
MyCancerGenomeBCL7A
Protein Interactions : CTD
Pharm GKB GenePA25314
PharosQ4VC05
Clinical trialBCL7A
Miscellaneous
canSAR (ICR)BCL7A (select the gene name)
HarmonizomeBCL7A
DataMed IndexBCL7A
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXBCL7A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:12:37 CET 2021
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