Atlas of Genetics and Cytogenetics in Oncology and Haematology


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BCO1 (beta-carotene oxygenase 1)

Identity

Alias_namesBCDO
BCDO1
BCMO1
beta-carotene 15, 15'-dioxygenase 1
beta-carotene 15,15'-monooxygenase 1
Alias_symbol (synonym)FLJ10730
BCMO
Other aliasBCO
HGNC (Hugo) BCO1
LocusID (NCBI) 53630
Atlas_Id 54084
Location 16q23.2  [Link to chromosome band 16q23]
Location_base_pair Starts at 81272296 and ends at 81324747 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BCO1 (16q23.2) / AAK1 (2p13.3)CMIP (16q23.2) / BCO1 (16q23.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BCO1   13815
Cards
Entrez_Gene (NCBI)BCO1  53630  beta-carotene oxygenase 1
AliasesBCDO; BCDO1; BCMO; BCMO1; 
BCO
GeneCards (Weizmann)BCO1
Ensembl hg19 (Hinxton)ENSG00000135697 [Gene_View]  chr16:81272296-81324747 [Contig_View]  BCO1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000135697 [Gene_View]  chr16:81272296-81324747 [Contig_View]  BCO1 [Vega]
ICGC DataPortalENSG00000135697
TCGA cBioPortalBCO1
AceView (NCBI)BCO1
Genatlas (Paris)BCO1
WikiGenes53630
SOURCE (Princeton)BCO1
Genetics Home Reference (NIH)BCO1
Genomic and cartography
GoldenPath hg19 (UCSC)BCO1  -     chr16:81272296-81324747 +  16q23.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)BCO1  -     16q23.2   [Description]    (hg38-Dec_2013)
EnsemblBCO1 - 16q23.2 [CytoView hg19]  BCO1 - 16q23.2 [CytoView hg38]
Mapping of homologs : NCBIBCO1 [Mapview hg19]  BCO1 [Mapview hg38]
OMIM115300   605748   
Gene and transcription
Genbank (Entrez)AF294900 AK001592 AK296011 BC022269 BC126210
RefSeq transcript (Entrez)NM_017429
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_012171 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)BCO1
Cluster EST : UnigeneHs.212172 [ NCBI ]
CGAP (NCI)Hs.212172
Alternative Splicing GalleryENSG00000135697
Gene ExpressionBCO1 [ NCBI-GEO ]   BCO1 [ EBI - ARRAY_EXPRESS ]   BCO1 [ SEEK ]   BCO1 [ MEM ]
Gene Expression Viewer (FireBrowse)BCO1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53630
GTEX Portal (Tissue expression)BCO1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HAY6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HAY6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HAY6
Splice isoforms : SwissVarQ9HAY6
PhosPhoSitePlusQ9HAY6
Domains : Interpro (EBI)Carotenoid_Oase   
Domain families : Pfam (Sanger)RPE65 (PF03055)   
Domain families : Pfam (NCBI)pfam03055   
Conserved Domain (NCBI)BCO1
DMDM Disease mutations53630
Blocks (Seattle)BCO1
SuperfamilyQ9HAY6
Human Protein AtlasENSG00000135697
Peptide AtlasQ9HAY6
HPRD12042
IPIIPI00307216   IPI00910011   
Protein Interaction databases
DIP (DOE-UCLA)Q9HAY6
IntAct (EBI)Q9HAY6
FunCoupENSG00000135697
BioGRIDBCO1
STRING (EMBL)BCO1
ZODIACBCO1
Ontologies - Pathways
QuickGOQ9HAY6
Ontology : AmiGOretinoid metabolic process  retinoid metabolic process  beta-carotene 15,15'-monooxygenase activity  beta-carotene 15,15'-monooxygenase activity  cytosol  vitamin A biosynthetic process  retinol metabolic process  retinal metabolic process  metal ion binding  oxidation-reduction process  beta-carotene metabolic process  
Ontology : EGO-EBIretinoid metabolic process  retinoid metabolic process  beta-carotene 15,15'-monooxygenase activity  beta-carotene 15,15'-monooxygenase activity  cytosol  vitamin A biosynthetic process  retinol metabolic process  retinal metabolic process  metal ion binding  oxidation-reduction process  beta-carotene metabolic process  
NDEx NetworkBCO1
Atlas of Cancer Signalling NetworkBCO1
Wikipedia pathwaysBCO1
Orthology - Evolution
OrthoDB53630
GeneTree (enSembl)ENSG00000135697
Phylogenetic Trees/Animal Genes : TreeFamBCO1
HOVERGENQ9HAY6
HOGENOMQ9HAY6
Homologs : HomoloGeneBCO1
Homology/Alignments : Family Browser (UCSC)BCO1
Gene fusions - Rearrangements
Fusion : MitelmanCMIP/BCO1 [16q23.2/16q23.2]  [t(16;16)(q23;q23)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBCO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BCO1
dbVarBCO1
ClinVarBCO1
1000_GenomesBCO1 
Exome Variant ServerBCO1
ExAC (Exome Aggregation Consortium)BCO1 (select the gene name)
Genetic variants : HAPMAP53630
Genomic Variants (DGV)BCO1 [DGVbeta]
DECIPHER (Syndromes)16:81272296-81324747  ENSG00000135697
CONAN: Copy Number AnalysisBCO1 
Mutations
ICGC Data PortalBCO1 
TCGA Data PortalBCO1 
Broad Tumor PortalBCO1
OASIS PortalBCO1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDBCO1
BioMutasearch BCO1
DgiDB (Drug Gene Interaction Database)BCO1
DoCM (Curated mutations)BCO1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BCO1 (select a term)
intoGenBCO1
Cancer3DBCO1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM115300    605748   
Orphanet18389   
MedgenBCO1
Genetic Testing Registry BCO1
NextProtQ9HAY6 [Medical]
TSGene53630
GENETestsBCO1
Huge Navigator BCO1 [HugePedia]
snp3D : Map Gene to Disease53630
BioCentury BCIQBCO1
ClinGenBCO1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD53630
Chemical/Pharm GKB GenePA37812
Clinical trialBCO1
Miscellaneous
canSAR (ICR)BCO1 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBCO1
EVEXBCO1
GoPubMedBCO1
iHOPBCO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:53:53 CEST 2017

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